Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cindy, Patinote"'
Autor:
Shaymaa Itani, Maguy Hamie, Reem El Jammal, Wassim Abdine, Mark Doumit, Adib Charafeddine, Marwan El-Sabban, Cindy Patinote, Carine Masquefa, Pierre-Antoine Bonnet, Makram Obeid, Hiba El Hajj
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1295 (2024)
Toxoplasma gondii is the etiologic agent of toxoplasmosis, a highly prevalent parasitosis. Toxoplasma gondii (T. gondii) transits in the brain from acute (AT) to chronic toxoplasmosis (CT), under host immune control. In immunocompromised patients, re
Externí odkaz:
https://doaj.org/article/172d8672ccec45c68561be7008137ae5
Autor:
Cindy Patinote, Sandy Raevens, Amélie Baumann, Eloise Pellegrin, Pierre-Antoine Bonnet, Carine Deleuze-Masquéfa
Publikováno v:
Molecules, Vol 28, Iss 14, p 5478 (2023)
Cutaneous melanoma is one of the most aggressive human cancers and is the deadliest form of skin cancer, essentially due to metastases. Novel therapies are always required, since cutaneous melanoma develop resistance to oncogenic pathway inhibition t
Externí odkaz:
https://doaj.org/article/3fe4f419bf2c46afb9661eec669a531f
Publikováno v:
Molecules, Vol 23, Iss 11, p 2987 (2018)
Imiqualines (imidazoquinoxaline derivatives) are anticancer compounds with high cytotoxic activities on melanoma cell lines. The first generation of imiqualines, with two lead compounds (EAPB0203 and EAPB0503), shows remarkable in vitro (IC50 = 1 570
Externí odkaz:
https://doaj.org/article/1ffa6c3090ab47cd98c51f50d59e7d11
Autor:
Carine Deleuze-Masquéfa, Soulaima Chamat, Issam Kassab, Nour Bou Karroum, Pierre-Antoine Bonnet, Cindy Patinote, Mona Diab-Assaf, Hasnaa Bouharoun-Tayoun, Jean-François Guichou, Pierre Cuq, Georges Moarbess
Publikováno v:
Journal of Medicinal Chemistry. 62:7015-7031
The Toll-like receptors (TLRs) 7 and 8 play an important role in the immune system activation, and their agonists may therefore serve as promising candidate vaccine adjuvants. However, the chronic immune activation by excessive TLR stimulation is a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f287a1be945fb10181dddf0365af346
https://doi.org/10.1021/acs.jmedchem.9b00411
https://doi.org/10.1021/acs.jmedchem.9b00411
Autor:
Carine Deleuze-Masquéfa, Kamel Hadj Kaddour, Pierre Cuq, Zahraa Zghaib, Cindy Patinote, Mona Diab Assaf, Laure-Anaïs Vincent, Pierre-Antoine Bonnet, Romain M. Larive, Jean-François Guichou
Publikováno v:
European journal of medicinal chemistry. 212
The malignant transformation of melanocytes causes several thousand deaths each year, making melanoma an important public health concern. Melanoma is the most aggressive skin cancer, which incidence has regularly increased over the past decades. We d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fcf57d0cba9e1394c97c8471cc66d6
https://pubmed.ncbi.nlm.nih.gov/33309473
https://pubmed.ncbi.nlm.nih.gov/33309473
Autor:
Natalina Cirnat, Carine Deleuze-Masquéfa, Kamel Hadj-Kaddour, Cindy Patinote, Pierre-Antoine Bonnet, Pierre Cuq
Publikováno v:
Journal of fluorescence. 30(6)
Fluorescent tools have revolutionized our capability to visualize, probe, study, and understand the biological cellular properties, processes and dynamics, enabling researchers to improve their knowledge for example in cancer field. In this paper, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616e8ac4d23a897cc739f3b5bc792b65
https://pubmed.ncbi.nlm.nih.gov/32778995
https://pubmed.ncbi.nlm.nih.gov/32778995
Autor:
Georges Moarbess, Natalina Cirnat, Nour Bou Karroum, Issam Kassab, Carine Deleuze-Masquéfa, Pierre-Antoine Bonnet, Cindy Patinote
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, ⟨10.1016/j.ejmech.2020.112238⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, ⟨10.1016/j.ejmech.2020.112238⟩
The discovery of the TLRs family and more precisely its functions opened a variety of gates to modulate immunological host responses. TLRs 7/8 are located in the endosomal compartment and activate a specific signaling pathway in a MyD88-dependant man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de7f9bd79045fce8ce9d640b42bd466
https://hal.archives-ouvertes.fr/hal-02826850
https://hal.archives-ouvertes.fr/hal-02826850
Autor:
Cindy Patinote, Nour Bou Karroum, Carine Deleuze-Masquéfa, Mona Diab-Assaf, Pierre Cuq, Georges Moarbess, Pierre-Antoine Bonnet, Issam Kassab
Publikováno v:
Chemistry of Heterocyclic Compounds. 54:183-187
The Suzuki–Miyaura cross coupling is a versatile and powerful reaction for carbon–carbon bond formation which nevertheless requires optimization of conditions. While the coupling of arylboron derivatives with aryl or alkenyl halides has been wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ead3b22ac22867697b29636349a8110
https://doi.org/10.1007/s10593-018-2252-8
https://doi.org/10.1007/s10593-018-2252-8
Autor:
Pierre-Antoine Bonnet, Marjorie Damian, Carine Deleuze-Masquéfa, Cindy Patinote, Kamel Hadj-Kaddour, Pierre Cuq
Publikováno v:
Journal of Fluorescence. 27:1607-1611
The fluorescence properties of eleven novel derivatives based on the imidazo[1,2-a]quinoxaline structures have been studied. The absorption and emission spectra of these compounds have been recorded in dimethylsulfoxide solution. The phenyl substitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fde230a72543f6b1fc50b34d6a4c657
https://doi.org/10.1007/s10895-017-2097-z
https://doi.org/10.1007/s10895-017-2097-z
Publikováno v:
Current medicinal chemistry. 28(4)
Heterocyclic compounds hold a huge and recognized place in the field of medicinal chemistry thanks to their multiple biological activities. Their synthetic pathways allow their easy and rapid access due to different bond-forming methodologies and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4702777d4908b6e928b74fac28180c5
https://pubmed.ncbi.nlm.nih.gov/32026768
https://pubmed.ncbi.nlm.nih.gov/32026768