Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cimen Karasu"'
Autor:
Hilal Ozlu, Ayse Cakir Gundogdu, Zubeyir Elmazoglu, Gulnur Take Kaplanoglu, Levent Oktar, Cimen Karasu
Publikováno v:
Journal of Investigative Surgery, Vol 34, Iss 9, Pp 935-946 (2021)
Objective To investigate the protective effect and underlying mechanisms of B. monnieri, a medicinal plant, on kidney and skeletal muscle injury induced by infra-renal abdominal aorta clamping for 2-hours (ischemia) and following removal of the clamp
Externí odkaz:
https://doaj.org/article/6cd94e38c3874100b076eb4912646a8f
Autor:
Lucia Kovacikova, Marta Soltesova Prnova, Magdalena Majekova, Andrej Bohac, Cimen Karasu, Milan Stefek
Publikováno v:
Molecules, Vol 26, Iss 10, p 2867 (2021)
Aldose reductase (AR, ALR2), the first enzyme of the polyol pathway, is implicated in the pathophysiology of diabetic complications. Aldose reductase inhibitors (ARIs) thus present a promising therapeutic approach to treat a wide array of diabetic co
Externí odkaz:
https://doaj.org/article/6c61c67ed6cc454da514cbd4def22db7
Autor:
Edgar Rangel-López, Benjamín Robles-Bañuelos, Natalia Guadiana-Ramírez, Valeria Alvarez-Garduño, Sonia Galván-Arzate, Cecilia Zazueta, Cimen Karasu, Isaac Túnez, Alexey Tinkov, Michael Aschner, Abel Santamaría
Publikováno v:
Neurotoxicity Research. 40:814-824
© 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Thallium (Tl+) is a heavy metal that causes toxicity in several organs, including the brain. Its cytotoxic profile, combined with its aff
Autor:
Rubén Estrada-Valencia, María Ester Hurtado-Díaz, Edgar Rangel-López, Socorro Retana-Márquez, Isaac Túnez, Alexey Tinkov, Cimen Karasu, Beatriz Ferrer, José Pedraza-Chaverri, Michael Aschner, Abel Santamaría
Publikováno v:
Neurotoxicity Research. 40:573-584
The development, at the experimental level, of therapeutic strategies based on natural products to attenuate neurological alterations in degenerative disorders has gained attention. Antioxidant molecules exhibit both anti-inflammatory and neuroprotec
Autor:
Carolina Y. Reyes-Soto, Ricardo J. Ramírez-Carreto, Luz Belinda Ortíz-Alegría, Alejandro Silva-Palacios, Cecilia Zazueta, Sonia Galván-Arzate, Çimen Karasu, Isaac Túnez, Alexey A. Tinkov, Michael Aschner, Tessy López-Goerne, Anahí-Chavarría, Abel Santamaría
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Glioblastoma (GBM) is an aggressive form of cancer affecting the Central Nervous System (CNS) of thousands of people every year. Redox alterations have been shown to play a key role in the development and progression of these tumors as React
Externí odkaz:
https://doaj.org/article/253d45e05a0a427a95f33bf3930f249b
Autor:
Karen Jaqueline, Paredes-Ruiz, Karla, Chavira-Ramos, Mario, Orozco-Morales, Cimen, Karasu, Alexey A, Tinkov, Michael, Aschner, Abel, Santamaría, Ana Laura, Colín-González
Publikováno v:
Neurotoxicity research. 39(6)
The endocannabinoid system (ECS) is composed of endogenous cannabinoids; components involved in their synthesis, transport, and degradation; and an expansive variety of cannabinoid receptors. Hypofunction or deregulation of the ECS is related to path
Publikováno v:
General physiology and biophysics. 34(4)
The increased activity of xanthine/xanthine oxidase (X/XO) has been suggested as a risk factor for heart disease and herbal polyphenols exhibits cardioprotection in vitro and in vivo. To understand the cardioprotective action mechanisms of polyphenol
Publikováno v:
Neuro endocrinology letters. 34(5)
The aim of this study was to reveal the effects of 4,5-dianilinophthalimide (DAPH), which inhibits amyloid β fibrillization, against serum deprivation (SD)-induced apoptosis and the possible mechanisms in differentiated PC12 neuron cells.Firstly, we
Publikováno v:
Neuro endocrinology letters. 31(3)
Recent basic research and clinical data have provided new insights into the role of glycoxidative and nitrosative stresses (both oxidative stress) in diabetic complications, such as diabetic nephropathy, suggesting a different and innovative approach