Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cillian E. Lynch"'
Autor:
Rachel Thomas, Cillian E. Lynch, Jeff Debad, Christopher Campbell, Onyinyechi Chidomere, Joseph Kilianski, Kan Ding, Christopher Madden, Danielle K. Sandsmark, Ramon Diaz-Arrastia, Joshua W. Gatson
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 655-662 (2023)
Each year in the United States, ?2.7 million persons seek medical attention for traumatic brain injury (TBI), of which ?85% are characterized as being mild brain injuries. Many different cell types in the brain are affected in these heterogeneous inj
Externí odkaz:
https://doaj.org/article/f9e06a3c8db5439ab51b4fc8bca415c1
Autor:
John K. Yue, Firas H. Kobeissy, Sonia Jain, Xiaoying Sun, Ryan R.L. Phelps, Frederick K. Korley, Raquel C. Gardner, Adam R. Ferguson, J. Russell Huie, Andrea L.C. Schneider, Zhihui Yang, Haiyan Xu, Cillian E. Lynch, Hansen Deng, Miri Rabinowitz, Mary J. Vassar, Sabrina R. Taylor, Pratik Mukherjee, Esther L. Yuh, Amy J. Markowitz, Ava M. Puccio, David O. Okonkwo, Ramon Diaz-Arrastia, Geoffrey T. Manley, Kevin K.W. Wang, Collaboration group, Neeraj Badjatia, Brandon Foreman, Shankar Gopinath, Ramesh Grandhi, Ruchira M. Jha, Hester F. Lingsma, Christopher Madden, Debbie Y. Madhok, Michael A. McCrea, Randall Merchant, Lindsay D. Nelson, Laura B. Ngwenya, Claudia S. Robertson, Richard B. Rodgers, Gabriela G. Satris, David M. Schnyer, Alex B. Valadka, Thomas A. van Essen, Ross Zafonte
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 171-183 (2023)
The relationship between systemic inflammation and secondary injury in traumatic brain injury (TBI) is complex. We investigated associations between inflammatory markers and clinical confirmation of TBI diagnosis and prognosis. The prospective TRACK-
Externí odkaz:
https://doaj.org/article/9cc684b83c2843f19ca58978f84419e7
Autor:
Franck Amyot, Cillian E. Lynch, John Ollinger, J. Kent Werner, E. Silverman, Carol Moore, Cora Davis, L. Christine Turtzo, Ramon Diaz-Arrastia, Kimbra Kenney
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
ObjectiveTo characterize the relationship between persistent post-traumatic headache (pPTH) and traumatic cerebrovascular injury (TCVI) in chronic traumatic brain injury (TBI). Cerebrovascular reactivity (CVR), a measure of the cerebral microvasculat
Externí odkaz:
https://doaj.org/article/932137137efd41a292d6f08215b4bdc6
Autor:
Dmitriy Petrov, Ramon Diaz-Arrastia, Junghoon Kim, My Duyen Le, Leroy Wesley, Erika Silverman, Pashtun Shahim, Hannah Zamore, Justin Morrison, Brigid Magdamo, Linda Xu, Cillian E Lynch, Jeffrey B. Ware, James M. Schuster, H. Isaac Chen, Cian Dabrowski, Danielle K. Sandsmark
Publikováno v:
J Neurotrauma
Imaging detection of brain perfusion alterations after traumatic brain injury (TBI) may provide prognostic insights. In this study, we used arterial spin labeling (ASL) to quantify cross-sectional and longitudinal changes in cerebral blood flow (CBF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aab2b16da89e39d0d94e8be438f94ba
https://doi.org/10.1089/neu.2020.7553
https://doi.org/10.1089/neu.2020.7553
Autor:
Daniel Paris, Charis Ringland, Ben Shackleton, Jonas Elias Schweig, Laila Abdullah, Maxwell Eisenbaum, Cillian E Lynch, Michael Mullan, Fiona Crawford, Corbin Bachmeier
Publikováno v:
Neurobiol Aging
Apolipoprotein E (APOE) has been shown to influence amyloid-β (Aβ) clearance from the brain in an isoform-specific manner. Our prior work showed that Aβ transit across the blood-brain-barrier was reduced by apoE4, compared to other apoE isoforms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b41e64fed619741a697ec4b4b4bd146
https://doi.org/10.1016/j.neurobiolaging.2020.06.018
https://doi.org/10.1016/j.neurobiolaging.2020.06.018
Autor:
Scott Ferguson, Joseph O. Ojo, Nicole Saltiel, Moustafa Algamal, Fiona Crawford, Cillian E Lynch, Ramon Diaz-Arrastia, Benoit Mouzon, Matilde Balbi, Michael Mullan, Corbin Bachmeier, Maxwell Eisenbaum
Publikováno v:
J Cereb Blood Flow Metab
Incidences of repetitive mild TBI (r-mTBI), like those sustained by contact sports athletes and military personnel, are thought to be a risk factor for development of neurodegenerative disorders. Those suffering from chronic TBI-related illness demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884d38d5507c36d26ad1cc6338526d43
https://doi.org/10.1177/0271678x20954015
https://doi.org/10.1177/0271678x20954015
Autor:
Carol Moore, Cillian E Lynch, Cora Davis, John Ollinger, L. Christine Turtzo, Ramon Diaz-Arrastia, Franck Amyot, Erika Silverman, J Kent Werner, Kimbra Kenney
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
ObjectiveTo characterize the relationship between persistent post-traumatic headache (pPTH) and traumatic cerebrovascular injury (TCVI) in chronic traumatic brain injury (TBI). Cerebrovascular reactivity (CVR), a measure of the cerebral microvasculat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226e8c5b605d7dbe23198d9155f2b69c
https://doi.org/10.3389/fphys.2021.649901
https://doi.org/10.3389/fphys.2021.649901
Autor:
Danielle K. Sandsmark, Kimbra Kenney, Ramon Diaz-Arrastia, Dzung L. Pham, John K Werner, Margalit Haber, Yiyu Chou, Sarah Woodson, Carol Moore, Erika Silverman, Cillian E Lynch, Franck Amyot, Kelley Flesher
Publikováno v:
J Cereb Blood Flow Metab
Traumatic Brain Injury (TBI) is associated with both diffuse axonal injury (DAI) and diffuse vascular injury (DVI), which result from inertial shearing forces. These terms are often used interchangeably, but the spatial relationships between DAI and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c511aa3cf79dc71977a0ea9f1b0abf08
https://pubmed.ncbi.nlm.nih.gov/33444092
https://pubmed.ncbi.nlm.nih.gov/33444092
Autor:
Utsav Joshi, Corbin Bachmeier, Joseph O. Ojo, Andrew Pearson, Fiona Crawford, Benoit Mouzon, Max Eisenbaum, Ben Shackleton, Daniel Paris, Michael Mullan, Nicole Saltiel, Cillian E Lynch, Charis Ringland
Publikováno v:
Neurobiology of disease
Neurobiology of Disease, Vol 150, Iss, Pp 105237-(2021)
Neurobiology of Disease, Vol 150, Iss, Pp 105237-(2021)
A pathological characteristic of repetitive traumatic brain injury (TBI) is the deposition of hyperphosphorylated and aggregated tau species in the brain and increased levels of extracellular monomeric tau are believed to play a role in the pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d899ff983e9b898a75ce392120c41ee7
https://doi.org/10.1016/j.nbd.2020.105237
https://doi.org/10.1016/j.nbd.2020.105237
Autor:
Joseph O. Ojo, Fiona Crawford, Benoit Mouzon, Michael Mullan, James F. Evans, William Stewart, Moustafa Algamal, Corbin Bachmeier, Paige Leary, Laila Abdullah, Cillian E Lynch
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 75:636-655
Exposure to repetitive mild traumatic brain injury (mTBI) is a risk factor for chronic traumatic encephalopathy, which is characterized by patchy deposition of hyperphosphorylated tau aggregates in neurons and astrocytes at the depths of cortical sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8d846e67d746e533fee359a21d3e03
https://doi.org/10.1093/jnen/nlw035
https://doi.org/10.1093/jnen/nlw035