Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Cigir Biray-Avci"'
Autor:
Cigir Biray Avci, Tuba Gokdogan Edgunlu, Tugba Suzek, Neslihan Pinar Ozates, Bakiye Goker Bagca, Aysegul Demirtas Bilgic, Cilem Ozdemir, Bakiye Ugur
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100186- (2024)
Long non-coding RNAs (lncRNAs) play a dynamic role in gene expression regulation and serve as potential therapeutic targets in breast cancer. The anticancer effect of propofol, an anesthetic agent, has been proven, but its interaction with lncRNAs ha
Externí odkaz:
https://doaj.org/article/fc3949b4c3f04d98a3418ebf0c210ae8
Autor:
Cigir Biray Avci, Bakiye Goker Bagca, Masoud Nikanfar, Leila Sabour Takanlou, Maryam Sabour Takanlou, Alireza Nourazarian
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The tumor microenvironment (TME) plays a crucial role in cancer development and metastasis. This review summarizes the current research on how the TME promotes metastasis through molecular pathways, focusing on key components, such as cancer-associat
Externí odkaz:
https://doaj.org/article/6413023622c646bea4fe6a5cb47eab51
Autor:
Cigir Biray Avci, Bakiye Goker Bagca, Behrouz Shademan, Leila Sabour Takanlou, Maryam Sabour Takanlou, Alireza Nourazarian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Cancer therapy is on the brink of a significant transformation with the inclusion of patient-derived organoids (PDOs) in drug development. These three-dimensional cell cultures, directly derived from a patient’s tumor, accurately replicate the comp
Externí odkaz:
https://doaj.org/article/19e3a26eab074868af1705be2ed26c68
Autor:
Narges Abolhasanzadeh, Sajed Sarabandi, Bahar Dehghan, Vahidreza Karamad, Cigir Biray Avci, Behrouz Shademan, Alireza Nourazarian
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Breast cancer stands as the most prevalent form of cancer among women globally, influenced by a combination of genetic and environmental factors. Recent studies have investigated changes in microRNAs (miRNAs) during breast cancer progression and the
Externí odkaz:
https://doaj.org/article/0baf3b010760493db05d95a3babb21c2
Autor:
Pelin Saglam-Metiner, Utku Devamoglu, Yagmur Filiz, Soheil Akbari, Goze Beceren, Bakiye Goker, Burcu Yaldiz, Sena Yanasik, Cigir Biray Avci, Esra Erdal, Ozlem Yesil-Celiktas
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Two engineering approaches, a rotating cell culture system (RCCS) and microfluidic platform (µ-platform), are presented with the goal of improving harvestability, scalability, reproducibility and survival of human brain organoids in long term cultur
Externí odkaz:
https://doaj.org/article/47a98e20a0cb47bca76c4812cf40f9e5
Autor:
Majid Tozihi, Behrouz Shademan, Hadi Yousefi, Cigir Biray Avci, Alireza Nourazarian, Gholamreza Dehghan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Cerebral ischemia-reperfusion (CIR) injury is initiated by the generation of reactive oxygen species (ROS), which leads to the oxidation of cellular proteins, DNA, and lipids as an initial event. The reperfusion process impairs critical cascades that
Externí odkaz:
https://doaj.org/article/eb079efc82c64118a1701410da6396f8
Autor:
Burcin Tezcanli Kaymaz, Nur Selvi Gunel, Fatma Sogutlu, Neslihan Pinar Ozates Ay, Yusuf Baran, Cumhur Gunduz, Cigir Biray Avci
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 7, Pp 904-912 (2022)
Objective(s): STATs are one of the initial targets of emerging anti-cancer agents due to their regulatory roles in survival, apoptosis, drug response, and cellular metabolism in CML. Aberrant STAT3 activity promotes malignancy, and acts as a metaboli
Externí odkaz:
https://doaj.org/article/ad167cc2cfda4ac980a8a157e2f2d7d8
Autor:
Zahra Alizadeh Shahabad, Cigir Biray Avci, Farhad Bani, Amir Zarebkohan, Majid Sadeghizadeh, Roya Salehi, Maryam Ghafarkhani, Reza Rahbarghazi, Bakiye Goker Bagca, Neslihan Pınar Ozates
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Here, we investigated the photothermal effect of gold nanorods (GNRs) on human neuroblastoma CD133+ cancer stem cells (CSCs) via autophagic cell death. GNRs were synthesized using Cetyltrimethylammonium bromide (CTAB), covered with bovine se
Externí odkaz:
https://doaj.org/article/673aa5901d5f43d98c3d80025937360f
Autor:
Maryam Ghafarkhani, Cigir Biray Avci, Reza Rahbarghazi, Abbas Karimi, Majid Sadeghizadeh, Amir Zarebkohan, Farhad Bani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Unraveling unwanted side effects of nanotechnology-based therapies like photothermal therapy (PTT) is vital in translational nanomedicine. Herein, we monitored the relationship between autophagic response at the transcriptional level by usin
Externí odkaz:
https://doaj.org/article/a1ab55f374de46e0b7570d1fdd70d1bc
Autor:
Behrouz Shademan, Cigir Biray Avci, Vahidreza Karamad, Gholamreza Jahangirzadeh Soureh, Jalhe Bagheri Hamzyan Olia, Farzaneh Esmaily, Alireza Nourazarian, Masoud Nikanfar
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 4, p 88 (2023)
Ischaemic stroke is a sudden neurological disorder caused by localised cerebral ischaemia and persistent cerebral infarction. Occlusion of large arteries due to atherothrombosis, cerebral embolism (i.e., embolic infarction), no thrombotic occlusion i
Externí odkaz:
https://doaj.org/article/e1a475e06e7746579f8f4f188e0b608c