Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cigdem Acioglu"'
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background Neuropathic pain is often observed in individuals with multiple sclerosis (MS) and spinal cord injury (SCI) and is not adequately alleviated by current pharmacotherapies. A better understanding of underlying mechanisms could facil
Externí odkaz:
https://doaj.org/article/13667b0f221a4a0e8f40857b650fa16e
Publikováno v:
Brain, Behavior, and Immunity
Highlights • Astroglial TLRs mediate host-defense and pathogen dissemination in CNS infections. • Astroglial TLRs help clearance of protein aggregates in neurodegenerative diseases. • Astroglial TLR signaling contributes to inflammation in CNS
Publikováno v:
Brain, behavior, and immunity. 102
Toll-like receptors (TLRs) are innate immune receptors that are expressed in immune cells as well as glia and neurons of the central and peripheral nervous systems. They are best known for their role in the host defense in response to pathogens and f
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundNeuropathic pain is often observed in individuals with multiple sclerosis (MS) and spinal cord injury (SCI) and is not adequately alleviated by current pharmacotherapies. A better understanding of underlying mechanisms could facilitate the
Autor:
Emel Akgun, Betul Sahin, Mete Bora Tuzuner, Zelal Adiguzel, Muge Serhatli, Cigdem Acioglu, Busra Gurel, Ahmet Tarik Baykal, Ceyda Acilan
Publikováno v:
Current Proteomics. 16:136-147
Background and Objective: Antimycin A (AntA) is a potent Electron Transport System (ETS) inhibitor exerting its effect through inhibiting the transfer of the electrons by binding to the quinone reduction site of the cytochrome bc1 complex (Complex II
Publikováno v:
Brain research. 1758
Classically, the loss of vulnerable neuronal populations in neurodegenerative diseases was considered to be the consequence of cell autonomous degeneration of neurons. However, progress in the understanding of glial function, the availability of impr
Autor:
Yuan Xiang Tao, Cigdem Acioglu, Ayomi Ratnayake, Lun Li, Li Ni, Stella Elkabes, Veronika Khariv, Robert F. Heary
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Earlier studies on genetically modified mice indicated that plasma membrane calcium ATPase 2 (PMCA2), a calcium extrusion pump, plays a novel and sex-dependent role in mechanical pain responses: female, but not male, PMCA2+/− mice manifest increase
Additional file 3. Absence of demyelination in the lumbar SC of C57Bl/6Ncrl mice with EAE at early disease phase. Lumbar SC sections, obtained from A) CFA- or B) MOG35–55-inoculated C57Bl/6Ncrl mice manifesting only flaccid tail, were stained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4429a9feb135656f52293d7675d9aed2
Autor:
Cigdem Acioglu, Robert F. Heary, Ersilia Mirabelli, Stella Elkabes, Ahmet Tarik Baykal, Ayomi Ratnayake, Li Ni
Publikováno v:
Brain, behavior, and immunity. 56
Toll like receptors (TLRs) are expressed by cells of the immune system and mediate the host innate immune responses to pathogens. However, increasing evidence indicates that they are important contributors to central nervous system (CNS) function in