Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Cigall Kadoch"'
Autor:
Gloria Mas, Na Man, Yuichiro Nakata, Concepcion Martinez-Caja, Daniel Karl, Felipe Beckedorff, Francesco Tamiro, Chuan Chen, Stephanie Duffort, Hidehiro Itonaga, Adnan K. Mookhtiar, Kranthi Kunkalla, Alfredo M. Valencia, Clayton K. Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Lluis Morey, Daniel Bilbao, Stephen D. Nimer
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
During emergency hematopoiesis, hematopoietic stem cells (HSCs) rapidly proliferate to produce myeloid and lymphoid effector cells, a response that is critical against infection or tissue injury. If unresolved, this process leads to sustained inflamm
Externí odkaz:
https://doaj.org/article/2118c0f847304f59b6180d6c918e01a4
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Autor:
Madison S Strine, Wesley L Cai, Jin Wei, Mia Madel Alfajaro, Renata B Filler, Scott B Biering, Sylvia Sarnik, Ryan D Chow, Ajinkya Patil, Kasey S Cervantes, Clayton K Collings, Peter C DeWeirdt, Ruth E Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G Doench, Patrick D Hsu, Cigall Kadoch, Qin Yan, Craig B Wilen
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002097 (2023)
Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We previously performed a genome-wi
Externí odkaz:
https://doaj.org/article/c10dd58b10dd439eb9610eccf28fbb91
Autor:
Xin Huang, Kyoung-mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary McKenzie, Laura A. Fischer, Chen Dong, Sabine Dietmann, Xiaoyun Xing, Pavel V. Shliaha, Jihong Yang, Dan Li, Junjun Ding, Tenzin Lungjangwa, Maya Mitalipova, Shafqat A. Khan, Sumeth Imsoonthornruksa, Nick Jensen, Ting Wang, Cigall Kadoch, Rudolf Jaenisch, Jianlong Wang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Although the interactors of pluripotency factors have been identified in mouse embryonic stem cells (ESCs), their interactors in human ESCs remain unexplored. Here the authors map OCT4 protein interactions in naïve and primed human ESCs to find spec
Externí odkaz:
https://doaj.org/article/475ca4c998cb484bb6963209f6ebdc13
Autor:
Andrew L Hong, Yuen-Yi Tseng, Jeremiah A Wala, Won-Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles WM Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William C Hahn
Publikováno v:
eLife, Vol 8 (2019)
Renal medullary carcinoma (RMC) is a rare and deadly kidney cancer in patients of African descent with sickle cell trait. We have developed faithful patient-derived RMC models and using whole-genome sequencing, we identified loss-of-function intronic
Externí odkaz:
https://doaj.org/article/ea9c3a1d96864bb8bbdbc626e575f019
Autor:
Jin Wei, Ajinkya Patil, Clayton K. Collings, Mia Madel Alfajaro, Yu Liang, Wesley L. Cai, Madison S. Strine, Renata B. Filler, Peter C. DeWeirdt, Ruth E. Hanna, Bridget L. Menasche, Arya Ökten, Mario A. Peña-Hernández, Jon Klein, Andrew McNamara, Romel Rosales, Briana L. McGovern, M. Luis Rodriguez, Adolfo García-Sastre, Kris M. White, Yiren Qin, John G. Doench, Qin Yan, Akiko Iwasaki, Thomas P. Zwaka, Jun Qi, Cigall Kadoch, Craig B. Wilen
Publikováno v:
Nature Genetics. 55:471-483
Identification of host determinants of coronavirus infection informs mechanisms of viral pathogenesis and can provide new drug targets. Here we demonstrate that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes, speci
Autor:
Megan A. Frederick, Kaylyn E. Williamson, Meilin Fernandez Garcia, Max B. Ferretti, Ryan L. McCarthy, Greg Donahue, Edgar Luzete Monteiro, Naomi Takenaka, Janice Reynaga, Cigall Kadoch, Kenneth S. Zaret
Publikováno v:
Nature Structural & Molecular Biology. 30:31-37
Autor:
Gloria Mas, Na Man, Yuichiro Nakata, Concepcion Martinez-Caja, Daniel L. Karl, Felipe Beckedorff, Francesco Tamiro, Chuan Chen, Stephanie Duffort, Hidehiro Itonaga, Adnan K. Mookhtiar, Kranthi Kunkalla, Alfredo M. Valencia, Clayton K. Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Lluis Morey, Daniel Bilbao, Stephen D. Nimer
Publikováno v:
Journal of Clinical Investigation.
Autor:
Toni K. Choueiri, Eliezer M. Van Allen, David J. Kwiatkowski, Matthew L. Freedman, Cigall Kadoch, Sabina Signoretti, X. Shirley Liu, F. Stephen Hodi, Marios Giannakis, Mark M. Awad, Robert I. Haddad, Guru Sonpavde, Andrew D. Cherniack, Sachet A. Shukla, Heng Du, Natalie I. Vokes, Claire A. Margolis, John A. Steinharter, Abdallah Flaifel, Taiwen Li, Yvonne Y. Li, Liam F. Spurr, Tarek H. Mouhieddine, Ronan Flippot, Pier Vitale Nuzzo, Sylvan C. Baca, David A. Braun, Jacob E. Berchuck, Ziad Bakouny, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi
Supplementary Figures and Legends for Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2b5cfb75769584bd872094b334867f
https://doi.org/10.1158/2326-6066.22543888.v1
https://doi.org/10.1158/2326-6066.22543888.v1
Autor:
Toni K. Choueiri, Eliezer M. Van Allen, David J. Kwiatkowski, Matthew L. Freedman, Cigall Kadoch, Sabina Signoretti, X. Shirley Liu, F. Stephen Hodi, Marios Giannakis, Mark M. Awad, Robert I. Haddad, Guru Sonpavde, Andrew D. Cherniack, Sachet A. Shukla, Heng Du, Natalie I. Vokes, Claire A. Margolis, John A. Steinharter, Abdallah Flaifel, Taiwen Li, Yvonne Y. Li, Liam F. Spurr, Tarek H. Mouhieddine, Ronan Flippot, Pier Vitale Nuzzo, Sylvan C. Baca, David A. Braun, Jacob E. Berchuck, Ziad Bakouny, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi
Prior data have variably implicated the inactivation of the mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) complex with increased tumor sensitivity to immune checkpoint inhibitors (ICI). Herein, we examined the association between mSWI/SNF varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020d009a5871cf452d37b9a8c131a880
https://doi.org/10.1158/2326-6066.c.6550447
https://doi.org/10.1158/2326-6066.c.6550447
Autor:
Toni K. Choueiri, Eliezer M. Van Allen, David J. Kwiatkowski, Matthew L. Freedman, Cigall Kadoch, Sabina Signoretti, X. Shirley Liu, F. Stephen Hodi, Marios Giannakis, Mark M. Awad, Robert I. Haddad, Guru Sonpavde, Andrew D. Cherniack, Sachet A. Shukla, Heng Du, Natalie I. Vokes, Claire A. Margolis, John A. Steinharter, Abdallah Flaifel, Taiwen Li, Yvonne Y. Li, Liam F. Spurr, Tarek H. Mouhieddine, Ronan Flippot, Pier Vitale Nuzzo, Sylvan C. Baca, David A. Braun, Jacob E. Berchuck, Ziad Bakouny, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40537fbf808db13b49b7ee07aad67707
https://doi.org/10.1158/2326-6066.22543885.v1
https://doi.org/10.1158/2326-6066.22543885.v1