Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease.

Autor: Kejia Zhang, Eldin, Patrick, Ciesla, Jessica H., Briant, Laurence, Lentini, Jenna M., Ramos, Jillian, Cobb, Justin, Munger, Joshua, Dragony Fu

Publikováno v: eLife; 5/30/2024, p1-27, 27p

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Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease.

Autor: Zhang K; Department of Biology, Center for RNA Biology, University of Rochester, Rochester, United States., Eldin P; Institut de Recherche en Infectiologie de Montpellier (IRIM), CNRS, UMR 9004, Université de Montpellier, Montpellier, France., Ciesla JH; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, United States., Briant L; Institut de Recherche en Infectiologie de Montpellier (IRIM), CNRS, UMR 9004, Université de Montpellier, Montpellier, France., Lentini JM; Department of Biology, Center for RNA Biology, University of Rochester, Rochester, United States., Ramos J; Department of Biology, Center for RNA Biology, University of Rochester, Rochester, United States., Cobb J; Department of Biology, Center for RNA Biology, University of Rochester, Rochester, United States., Munger J; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, United States., Fu D; Department of Biology, Center for RNA Biology, University of Rochester, Rochester, United States.

Publikováno v: ELife [Elife] 2024 May 30; Vol. 12. Date of Electronic Publication: 2024 May 30.