Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cierra Carafice"'
Autor:
Kylene P. Daily, Asmaa Badr, Mostafa Eltobgy, Shady Estfanous, Owen Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew McNamara, Kaitlin Hamilton, Samuel Houle, Spandan Gupta, Gauruv A. Gupta, Shruthi Madhu, Julie Fitzgerald, Abbey A. Saadey, Brooke Laster, Pearlly Yan, Amy Webb, Xiaoli Zhang, Maciej Pietrzak, Olga N. Kokiko-Cochran, Hazem E. Ghoneim, Amal O. Amer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is the sixth leading cause of death in the USA. It is established that neuroinflammation contributes to the synaptic loss, neuronal death, and symptomatic decline of AD patients. Accumulating evidence suggests a cr
Externí odkaz:
https://doaj.org/article/e9004d48993349bc9f739f58c680a79a
Autor:
Shady Estfanous, Kathrin Krause, Midhun N. K. Anne, Mostafa Eltobgy, Kyle Caution, Arwa Abu Khweek, Kaitlin Hamilton, Asmaa Badr, Kylene Daily, Cierra Carafice, Daniel Baetzhold, Xiaoli Zhang, Tianliang Li, Haitao Wen, Mikhail A. Gavrilin, Hesham Haffez, Sameh Soror, Amal O. Amer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe life threatening systemic infections in immunocompromised individuals including cystic fibrosis patients. The lack of gasdermin D (GSDMD) protects mice a
Externí odkaz:
https://doaj.org/article/dfc42d70a6394957ad2316ed4514e290
Autor:
Shady Estfanous, Kathrin Krause, Midhun N. K. Anne, Mostafa Eltobgy, Kyle Caution, Arwa Abu Khweek, Kaitlin Hamilton, Asmaa Badr, Kylene Daily, Cierra Carafice, Daniel Baetzhold, Xiaoli Zhang, Tianliang Li, Haitao Wen, Mikhail A. Gavrilin, Hesham Haffez, Sameh Soror, Amal O. Amer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/cfdde74256e840cda4a31d10563b25fc
Autor:
Asmaa Badr, Mostafa Eltobgy, Kathrin Krause, Kaitlin Hamilton, Shady Estfanous, Kylene P. Daily, Arwa Abu Khweek, Ahmad Hegazi, Midhun N. K. Anne, Cierra Carafice, Frank Robledo-Avila, Youssra Saqr, Xiaoli Zhang, Tracey L. Bonfield, Mikhail A. Gavrilin, Santiago Partida-Sanchez, Stephanie Seveau, Estelle Cormet-Boyaka, Amal O. Amer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Cystic fibrosis (CF) human and mouse macrophages are defective in their ability to clear bacteria such as Burkholderia cenocepacia. The autophagy process in CF (F508del) macrophages is halted, and the underlying mechanism remains unclear. Furthermore
Externí odkaz:
https://doaj.org/article/db95827f79284dbaa804f925acce7f81
Autor:
Shady Estfanous, Kylene P. Daily, Mostafa Eltobgy, Nicholas P. Deems, Midhun N. K. Anne, Kathrin Krause, Asmaa Badr, Kaitlin Hamilton, Cierra Carafice, Ahmad Hegazi, Arwa Abu Khweek, Hesham Kelani, Shahid Nimjee, Hamdy Awad, Xiaoli Zhang, Estelle Cormet-Boyaka, Hesham Haffez, Sameh Soror, Adel Mikhail, Gerard Nuovo, Ruth M. Barrientos, Mikhail A. Gavrilin, Amal O. Amer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Autophagy is a proposed route of amyloid-β (Aβ) clearance by microglia that is halted in Alzheimer’s Disease (AD), though mechanisms underlying this dysfunction remain elusive. Here, primary microglia from adult AD (5xFAD) mice were utilized to d
Externí odkaz:
https://doaj.org/article/a9bb136f3f4c4634b5d53a535a5644ae
Autor:
Cierra Carafice, Midhun N. K. Anne, Amal O. Amer, Xiaoli Zhang, Mostafa Eltobgy, Arwa Abu Khweek, Kathrin Krause, Mikhail A. Gavrilin, Shady Estfanous, Kylene Daily, Jeffrey R. Tonniges, Kaitlin Hamilton, Narasimham L. Parinandi, Asmaa Badr, Daniel Baetzhold
Publikováno v:
J Cyst Fibros
Background Mitochondria play a key role in immune defense pathways, particularly for macrophages. We and others have previously demonstrated that cystic fibrosis (CF) macrophages exhibit weak autophagy activity and exacerbated inflammatory responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb81922e6e56f4fd9397be406f5df681
https://doi.org/10.1016/j.jcf.2020.10.006
https://doi.org/10.1016/j.jcf.2020.10.006
Autor:
Mostafa M. Eltobgy, Ashley Zani, Adam D. Kenney, Shady Estfanous, Eunsoo Kim, Asmaa Badr, Cierra Carafice, Kylene Daily, Owen Whitham, Maciej Pietrzak, Amy Webb, Jeffrey Kawahara, Adrian C. Eddy, Parker Denz, Mijia Lu, Mahesh KC, Mark E. Peeples, Jianrong Li, Jian Zhu, Jianwen Que, Richard Robinson, Oscar Rosas Mejia, Rachael E. Rayner, Luanne Hall-Stoodley, Stephanie Seveau, Mikhail A. Gavrilin, Xiaoli Zhang, Jeronay Thomas, Jacob E. Kohlmeier, Mehul S. Suthar, Eugene Oltz, Andrea Tedeschi, Frank H. Robledo-Avila, Santiago Partida-Sanchez, Emily A. Hemann, Eman Abdelrazik, Adriana Forero, Shahid M. Nimjee, Prosper N. Boyaka, Estelle Cormet-Boyaka, Jacob S. Yount, Amal O. Amer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(21)
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health concern, and new treatment strategies are needed. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d41407d3800934f9acfc60d7cf1ba2d
https://pubmed.ncbi.nlm.nih.gov/35588457
https://pubmed.ncbi.nlm.nih.gov/35588457
Autor:
Ashley E. Russell, Asmaa Badr, Ali Rai, Cierra Carafice, Ansaar Rai, Kylene P. Daily, Owen Whitham, Amal O. Amer, Candice M. Brown, Duaa Dakhlallah
Publikováno v:
Nutritional Neurosciences ISBN: 9789811692048
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5756bb4cef9204fec5718476cc50b14
https://doi.org/10.1007/978-981-16-9205-5_13
https://doi.org/10.1007/978-981-16-9205-5_13
Autor:
Emily Hemann, Mark E. Peeples, Eman Abdelrazik, Estelle Cormet-Boyaka, Asmaa Badr, Prosper N. Boyaka, Maciej Pietrzak, Shady Estfanous, Jeffrey Kawahara, Ashley Zani, Krishnan Mahesh, Adam D. Kenney, Jianrong Li, Oscar Rosas Mejia, Mostafa Eltobgy, Owen Whitham, Shahid M Nimjee, Richard T. Robinson, Andrea Tedeschi, Santiago Partida-Sanchez, Parker J. Denz, Frank Roberto, Adrian Eddy, Jacob S. Yount, Amy Webb, Cierra Carafice, Rachael E. Rayner, Eunsoo Kim, Mikhail A. Gavrilin, Kylene Daily, Jian Zhu, Amal O. Amer, Jianwen Que, Luanne Hall-Stoodley, Adriana Forero, Mijia Lu, Stephanie Seveau
SARS-CoV-2 is a worldwide health concern, and new treatment strategies are needed 1. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain elusive. Here, we show that human caspase-4 (CASP4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af96809a1af3397cecceec5bce8d10b8
https://doi.org/10.1101/2021.09.24.461743
https://doi.org/10.1101/2021.09.24.461743
Autor:
Shady Estfanous, Midhun N. K. Anne, Kara N. Corps, Kathrin Krause, Mostafa Eltobgy, Cierra Carafice, Zayed Attia, Kylene Daily, Eunsoo Kim, Prosper N. Boyaka, Kaitlin Hamilton, Mikhail A. Gavrilin, Asmaa Badr, Arwa Abu Khweek, Marisa R. Joldrichsen, Xiaoli Zhang, Amal O. Amer
Publikováno v:
Cell Immunol
Asthma is an inflammatory lung disorder characterized by mucus hypersecretion, cellular infiltration, and bronchial hyper-responsiveness. House dust mites (HDM) are the most prevalent cause of allergic sensitization. Canonical and noncanonical inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea6266f03546a5d0d5a001ce3cc1876
https://pubmed.ncbi.nlm.nih.gov/34800762
https://pubmed.ncbi.nlm.nih.gov/34800762