In vitro assessment of cobalt oxide particle dissolution in simulated lung fluids for identification of new decorporating agents

Autor: Cien Yoong Hee, Véronique Malard, Christelle Gateau, Magali Floriani, Pauline Brunquet, Guillaume Drouet, Sylvie Coudert, Catherine Berthomieu, Célia Gouzerh, Anne Van der Meeren, Bastien Trochaud, Myriam Benameur, David Lemaire, Pascale Delangle, Colette Lebrun

Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2020, 66, pp.104863. ⟨10.1016/j.tiv.2020.104863⟩
Toxicology in Vitro, 2020, 66, pp.104863. ⟨10.1016/j.tiv.2020.104863⟩

Inhalation of 60Co3O4 particles may occur at the work place in nuclear industry. Their low solubility may result in chronic lung exposure to γ rays. Our strategy for an improved therapeutic approach is to enhance particle dissolution to facilitate c

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https://hal.archives-ouvertes.fr/hal-02922342/document