Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Cielo Pasay"'
Autor:
Michelle L. Gatton, David Smith, Cielo Pasay, Karen Anderson, Selam Mihreteab, Hugo O. Valdivia, Juan F. Sanchez, Khalid B. Beshir, Jane Cunningham, Qin Cheng
Publikováno v:
International Journal of Infectious Diseases, Vol 144, Iss , Pp 107061- (2024)
Objectives: The accuracy of malaria rapid diagnostic tests is threatened by Plasmodium falciparum with pfhrp2/3 deletions. This study compares gene deletion prevalence determined by multiplex real time polymerase chain reaction (qPCR) and conventiona
Externí odkaz:
https://doaj.org/article/f79bf97ed505439597db3c774d2a58d2
Autor:
Bosco B. Agaba, David Smith, Jye Travis, Cielo Pasay, Monica Nabatanzi, Emmanuel Arinaitwe, Isaac Ssewanyana, Susan Nabadda, Jane Cunningham, Moses R. Kamya, Qin Cheng
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background Rapid diagnostic tests (RDTs) that detect Plasmodium falciparum histidine-rich protein-2 (PfHRP2) are exclusively deployed in Uganda, but deletion of the pfhrp2/3 target gene threatens their usefulness as malaria diagnosis and sur
Externí odkaz:
https://doaj.org/article/fb437d6468c54ea1b80bc63f5c0f3c6d
Autor:
Hugo O. Valdivia, Karen Anderson, David Smith, Cielo Pasay, Carola J. Salas, Greys Braga, Carmen M. Lucas, Stephen E. Lizewski, Christie A. Joya, Jennifer M. Kooken, Juan F. Sanchez, Qin Cheng
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Peru was the first country where pfhrp2 and pfhrp3 gene deletions were detected despite the fact that rapid diagnostics tests are not commonly used for confirmatory malaria diagnosis. This context provides a unique scenario to study the dyna
Externí odkaz:
https://doaj.org/article/a48e4a9065c54a608aab3a7f28cd4913
Autor:
Selam Mihreteab, Karen Anderson, Cielo Pasay, David Smith, Michelle L. Gatton, Jane Cunningham, Araia Berhane, Qin Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Eritrea was the first African country to complete a nationwide switch in 2016 away from HRP2-based RDTs due to high rates of false-negative RDT results caused by Plasmodium falciparum parasites lacking hrp2/hrp3 genes. A cross-sectional surv
Externí odkaz:
https://doaj.org/article/5494a373c2b044e0b5d698ee29561c52
Autor:
Lena Chng, Deborah C Holt, Matt Field, Joshua R Francis, Dev Tilakaratne, Milou H Dekkers, Greg Robinson, Kate Mounsey, Rebecca Pavlos, Asha C Bowen, Katja Fischer, Anthony T Papenfuss, Robin B Gasser, Pasi K Korhonen, Bart J Currie, James S McCarthy, Cielo Pasay
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009149 (2021)
BackgroundThe suboptimal sensitivity and specificity of available diagnostic methods for scabies hampers clinical management, trials of new therapies and epidemiologic studies. Additionally, parasitologic diagnosis by microscopic examination of skin
Externí odkaz:
https://doaj.org/article/515d090e2c6947048554f98dbe118ace
Autor:
Rebecca E Watts, Anand Odedra, Louise Marquart, Lachlan Webb, Azrin N Abd-Rahman, Laura Cascales, Stephan Chalon, Maria Rebelo, Zuleima Pava, Katharine A Collins, Cielo Pasay, Nanhua Chen, Christopher L Peatey, Jörg J Möhrle, James S McCarthy
Publikováno v:
PLoS Medicine, Vol 17, Iss 8, p e1003203 (2020)
BackgroundArtemisinin resistance is threatening malaria control. We aimed to develop and test a human model of artemisinin-resistant (ART-R) Plasmodium falciparum to evaluate the efficacy of drugs against ART-R malaria.Methods and findingsWe conducte
Externí odkaz:
https://doaj.org/article/f0e834c76c4545578dd2dc713b5572d9
Autor:
Rebecca Pawliw, Rebecca Farrow, Silvana Sekuloski, Helen Jennings, Julie Healer, Thuan Phuong, Pri Sathe, Cielo Pasay, Krystal Evans, Alan F. Cowman, Louis Schofield, Nanhua Chen, James McCarthy, Katharine Trenholme
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background Although the use of induced blood stage malaria infection has proven to be a valuable tool for testing the efficacy of vaccines and drugs against Plasmodium falciparum, a limiting factor has been the availability of Good Manufactu
Externí odkaz:
https://doaj.org/article/afed1c50820b48f497a9eb2b6f34ff09
Autor:
Paul Griffin, Cielo Pasay, Suzanne Elliott, Silvana Sekuloski, Maggy Sikulu, Leon Hugo, David Khoury, Deborah Cromer, Miles Davenport, Jetsumon Sattabongkot, Karen Ivinson, Christian Ockenhouse, James McCarthy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 12, p e0005139 (2016)
BACKGROUND:Interventions to interrupt transmission of malaria from humans to mosquitoes represent an appealing approach to assist malaria elimination. A limitation has been the lack of systems to test the efficacy of such interventions before proceed
Externí odkaz:
https://doaj.org/article/c69ef26a80be445cbc33a06ebe6523cd
Autor:
Sumudu Britton, Qin Cheng, Matthew J Grigg, Catherine B Poole, Cielo Pasay, Timothy William, Kimberley Fornace, Nicholas M Anstey, Colin J Sutherland, Chris Drakeley, James S McCarthy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004443 (2016)
INTRODUCTION:Plasmodium vivax malaria has a wide geographic distribution and poses challenges to malaria elimination that are likely to be greater than those of P. falciparum. Diagnostic tools for P. vivax infection in non-reference laboratory settin
Externí odkaz:
https://doaj.org/article/072e831a17a14f40b939212e9476eda3
Autor:
Wesley Donald, Cielo Pasay, Jean-Olivier Guintran, Harry Iata, Karen Anderson, Johnny Nausien, Karryn J Gresty, Norman C Waters, Lasse S Vestergaard, George Taleo, Qin Cheng
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167136 (2016)
As part of efforts to eliminate malaria, Vanuatu has piloted the implementation of enhanced malaria surveillance and response strategies since 2011. This involves passive case detection (PCD) in health facilities, proactive case detection (Pro-ACD) a
Externí odkaz:
https://doaj.org/article/7a4d9ac63e174f81884fee4fcae2e00b