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Oxidative stress and mitochondrial dysfunction contributes to postoperative cognitive dysfunction in elderly rats dependent on NLRP3 activation.

Autor: Bonfante S; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Netto MB; University of South Santa Catarina, Tubarao, SC, Brazil., de Oliveira Junior AN; University of South Santa Catarina, Tubarao, SC, Brazil., Mathias K; University of South Santa Catarina, Tubarao, SC, Brazil., Machado RS; University of South Santa Catarina, Tubarao, SC, Brazil., Joaquim L; University of South Santa Catarina, Tubarao, SC, Brazil., Cidreira T; University of South Santa Catarina, Tubarao, SC, Brazil., da Silva MG; University of South Santa Catarina, Tubarao, SC, Brazil., Daros GC; University of South Santa Catarina, Tubarao, SC, Brazil., Danielski LG; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Gava F; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., da Silva Lemos I; Laboratory of Neurometabolic Diseases, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Matiola RT; Laboratory of Neurometabolic Diseases, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Córneo E; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Prophiro JS; University of South Santa Catarina, Tubarao, SC, Brazil., de Bitencourt RM; University of South Santa Catarina, Tubarao, SC, Brazil., Catalão CHR; Department of Neurosciences and Behavioral Sciences, Ribeirao Preto Medical School, University of Sao Paulo (USP), Ribeirao Preto, SP, Brazil.; Faillace Department of Psychiatry and Behavioural Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA., da Silva Generoso J; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Streck EL; Laboratory of Neurometabolic Diseases, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Dal-Pizzol F; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil., Barichello T; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil.; Faillace Department of Psychiatry and Behavioural Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA., Petronilho F; Laboratory of Experimental Neurology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciuma, SC, Brazil. fabriciapetronilho@unesc.net.; Laboratório de Neurobiologia Experimental, Programa de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil. fabriciapetronilho@unesc.net.

Publikováno v: Metabolic brain disease [Metab Brain Dis] 2024 Nov 13; Vol. 40 (1), pp. 1. Date of Electronic Publication: 2024 Nov 13.