Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Cicero de Oliveira Costa"'
1
Electrochemical, spectroscopic and pharmacological approaches toward the understanding of biflorin DNA damage effects
Autor: Cicero de Oliveira Costa, Raquel Carvalho Montenegro, Letícia V. Costa-Lotufo, Fabiane C. de Abreu, Marília O. F. Goulart, Camila Calado de Vasconcelos, Telma L. G. Lemos, Emanuella Gomes da Silva Terto, Marne Carvalho de Vasconcellos, Maria Aline F.B. de Moura
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The present study aims to evaluate some aspects of the pharmacoelectrochemistry of biflorin, a biologically active 1,2-naphthoquinone derivative, isolated from the roots of Capraria biflora. Electrochemical experiments involving biflorin using single
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5c88efc313b4ec2eb3b36283f21844
https://doi.org/10.1016/j.jelechem.2015.09.040
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2
Electrochemical and computational studies, in protic medium, of Morita-Baylis-Hillman adducts and correlation with leishmanicidal activity
Autor: Cicero de Oliveira Costa, Fábio P.L. Silva, Mário L. A. A. Vasconcellos, Yen G. de Paiva, Claudio G. Lima-Junior, Antonio A. de Souza, Marília O. F. Goulart, Waldomiro Pinho Júnior
Publikováno v: Electrochimica Acta. 140:557-563
Enzymatic bioreduction of nitro groups plays an important role on the activity of biologically active nitroaromatic compounds. Electrochemical methods are useful tools to simulate in vivo metabolic processes. This work presents electrochemical studie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fc46c7dbd9fd2f562712ef66e58a053
https://doi.org/10.1016/j.electacta.2014.05.066
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3
Preclinical Genotoxicology of Nor-β-lapachone in Human Cultured Lymphocytes and Chinese Hamster Lung Fibroblasts
Autor: Marília O. F. Goulart, Cicero de Oliveira Costa, Fabiane C. de Abreu, José Roberto de Oliveira Ferreira, Hemerson Iury Ferreira Magalhães, Manoel Odorico de Moraes, Francisco W.A. Barros, Hélio Vitoriano Nobre Júnior, Bruno C. Cavalcanti, Cláudia Pessoa, Igor O. Cabral, Eufrânio N. da Silva Júnior
Publikováno v: Chemical Research in Toxicology. 24:1560-1574
Nor-β-lapachone has shown several biological properties. Regarding cytotoxic activity against cancer cell lines, it has been recognized as an important prototype. However, quinonoid drugs present a major challenge because of their toxicity. In this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bc7093fd8ec9a6e7d4706f55f1a400
https://doi.org/10.1021/tx200180y
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4
Electrochemical determination of oncocalyxone A using an iron-phthalocyanine/iron-porphyrin modified glassy carbon electrode
Autor: Telma L. G. Lemos, Antonio A. de Souza, Lauro T. Kubota, Marília O. F. Goulart, Cicero de Oliveira Costa, Rita de Cássia Silva Luz, Otília Deusdênia L. Pessoa
Publikováno v: Journal of the Brazilian Chemical Society, Volume: 19, Issue: 4, Pages: 697-703, Published: 2008
Journal of the Brazilian Chemical Society v.19 n.4 2008
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
The development of a highly sensitive voltammetric sensor for oncocalyxone A using a glassy carbon electrode modified with a bilayer iron(II) tetrasulfonated phthalocyanine (FeTSPc) and iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) is des
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e1c9df83b32cbaeda840e7d7baef2a
https://doi.org/10.1590/s0103-50532008000400013
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5
Development of a voltammetric sensor for diospyrin determination in nanomolar concentrations
Autor: Paulo Rogério Barbosa de Miranda, Madhushree Das Sarma, Rita de Cássia Silva Luz, Cicero de Oliveira Costa, Marília O. F. Goulart, Lauro T. Kubota, Banasri Hazra
Publikováno v: Talanta. 68:1378-1383
A sensor based on glassy carbon (GC) electrode modified with cobalt tetrasulfonated phthalocyanine (CoTSPc) and a poly- l -lysine (PLL) film is proposed for diospyrin determination in nanomolar concentrations with differential pulse voltammetry (DPV)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8ecc9247394ff61bb808e4fca2adcd
https://doi.org/10.1016/j.talanta.2005.08.001
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6
Oncocalyxone A: electrochemical, spectroscopic investigation and studies of its interaction with DNA, nucleobases and N-acetylcysteine
Autor: Telma L. G. Lemos, Marília O. F. Goulart, Fabricia da Rocha Ferreira, Fabiane C. de Abreu, Claudio Olea-Azar, Otília Deusdênia L. Pessoa, Francisco de Assis dos Santos Silva, Benjamín Aguilera-Venegas, Edson S. Bento, Erivaldo de Oliveira Costa, Leonardo Vieira da Silva, Waldomiro Pinho Jr., Ester Norambuena, Cicero de Oliveira Costa, Luciana da S. Viana, Isis M. Figueiredo
Publikováno v: Journal of the Brazilian Chemical Society v.23 n.6 2012
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 23, Issue: 6, Pages: 1174-1185, Published: JUN 2012
ResearcherID
The formation of paramagnetic species from oncocalyxone A in aprotic medium was confirmed by performing in situ electrochemical-electron spin resonance (E-ESR) experiments. The high delocalization of the radical generated at the first reduction poten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107e6110f7c7aae0c6df3119f9e801ee
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532012000600024
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7
Determination of the pKa values of some biologically active and inactive hydroxyquinones
Autor: Fabiane C. de Abreu, Cicero de Oliveira Costa, Dorota Zarzeczanska, Tadeusz Ossowski, Piotr Falkowski, Paulo Rogério Barbosa de Miranda, Marília O. F. Goulart, Adam Liwo, Antônio Euzébio Goulart Santana
Publikováno v: Journal of the Brazilian Chemical Society v.19 n.1 2008
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 19, Issue: 1, Pages: 175-183, Published: 2008
The apparent dissociation constants (pKa) of four 2-hydroxynaphthoquinones, differently substituted at C-3, were determined in water:ethanol (1:1, v/v) solutions by pH-metric and hybrid pH-metric/UV titration methods. Isolapachol (pKa < 6) was more a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7625aa8782cb633d979ba2f1d54ab78
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000100025
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8
Growth inhibitory effects of 3′-nitro-3-phenylamino nor-beta-lapachone against HL-60: A redox-dependent mechanism
Autor: Cicero de Oliveira Costa, Danilo D. Rocha, Letícia V. Costa-Lotufo, Raquel Carvalho Montenegro, Jose Delano Barreto Marinho-Filho, Cláudia Pessoa, Victor Ferreira, A. A. de Souza, Marília O. F. Goulart, E.N. da Silva Júnior, Ana Jérsia Araújo, M. A. B. F. De Moura, Antonio V. Pinto, Marne Carvalho de Vasconcellos, F. C. De Abreu, M. O. de Moraes
Publikováno v: Toxicology in Vitro. (4):585-594
In this study, the cytotoxicity, genotoxicity and early ROS generation of 2,2-dimethyl-(3 H )-3-( N -3′-nitrophenylamino)naphtho[1,2- b ]furan-4,5-dione (QPhNO 2 ) were investigated and compared with those of its precursor, nor-beta-lapachone (nor-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c720235a40724bf4d017c8513ab7440c
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