Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Cicely A. Jette"'
Autor:
Mattie J. Casey, Priya P. Chan, Qing Li, Ju-Fen Zu, Cicely A. Jette, Missia Kohler, Benjamin R. Myers, Rodney A. Stewart
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114559- (2024)
Summary: Medulloblastoma (MB) is the most common malignant brain tumor in children and is stratified into three major subgroups. The Sonic hedgehog (SHH) subgroup represents ∼30% of all MB cases and has significant survival disparity depending upon
Externí odkaz:
https://doaj.org/article/70661191396a44ad9a078ff7db971aa4
Autor:
Mattie J. Casey, Alexandra M. Call, Annika V. Thorpe, Cicely A. Jette, Michael E. Engel, Rodney A. Stewart
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105737- (2023)
Summary: Lsd1/Kdm1a functions both as a histone demethylase enzyme and as a scaffold for assembling chromatin modifier and transcription factor complexes to regulate gene expression. The relative contributions of Lsd1’s demethylase and scaffolding
Externí odkaz:
https://doaj.org/article/e4086ce0d1e44269a796aa91edc20947
Autor:
Katarzyna Modzelewska, Elena F. Boer, Timothy L. Mosbruger, Daniel Picard, Daniela Anderson, Rodney R. Miles, Mitchell Kroll, William Oslund, Theodore J. Pysher, Joshua D. Schiffman, Randy Jensen, Cicely A. Jette, Annie Huang, Rodney A. Stewart
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1255-1264 (2016)
Summary: Malignant brain tumors are the leading cause of cancer-related deaths in children. Primitive neuroectodermal tumors of the CNS (CNS-PNETs) are particularly aggressive embryonal tumors of unknown cellular origin. Recent genomic studies have c
Externí odkaz:
https://doaj.org/article/d49d49aa85484923af1ac852839c57c6
Autor:
Laura Jimenez, Jindong Wang, Monique A. Morrison, Clifford Whatcott, Katherine K. Soh, Steven Warner, David Bearss, Cicely A. Jette, Rodney A. Stewart
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 389-400 (2016)
The epithelial-to-mesenchymal transition (EMT) is a highly conserved morphogenetic program essential for embryogenesis, regeneration and cancer metastasis. In cancer cells, EMT also triggers cellular reprogramming and chemoresistance, which underlie
Externí odkaz:
https://doaj.org/article/b5758c079b3648408920bc95ef03755c
Autor:
Itrat Harrold, Seth Carbonneau, Bethany M. Moore, Gina Nguyen, Nicole M. Anderson, Amandeep S. Saini, John P. Kanki, Cicely A. Jette, Hui Feng
Publikováno v:
BioTechniques, Vol 60, Iss 1, Pp 13-20 (2016)
The zebrafish represents a revolutionary tool in large-scale genetic and small-molecule screens for gene and drug discovery. Transgenic zebrafish are often utilized in these screens. Many transgenic fish lines are maintained in the heterozygous state
Externí odkaz:
https://doaj.org/article/05e674b2246d4a1fa844f1110e04d58a
Autor:
Mattie J. Casey, Alexandra M. Call, Annika V. Thorpe, Cicely A. Jette, Michael E. Engel, Rodney A. Stewart
Publikováno v:
iScience. 26(1)
Lsd1/Kdm1a functions both as a histone demethylase enzyme and as a scaffold for assembling chromatin modifier and transcription factor complexes to regulate gene expression. The relative contributions of Lsd1's demethylase and scaffolding functions d
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004946 (2015)
Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial skeleton. Extensive filopodial protrusions in NC cells are thought to sense chemo-attractive/repulsive signals that provide
Externí odkaz:
https://doaj.org/article/85552832a5dc480990cc0b2df93777ab
Autor:
Hui Feng, Kyoko Hayakawa, Jennifer Rhodes, Yue-Sheng Li, Cicely A. Jette, Richard R. Hardy, A. Thomas Look, Lingjuan Tang, Susan A. Shinton, Xingjun Liu
Publikováno v:
The Journal of Immunology. 199:1706-1715
CD79a and CD79b proteins associate with Ig receptors as integral signaling components of the B cell Ag receptor complex. To study B cell development in zebrafish, we isolated orthologs of these genes and performed in situ hybridization, finding that
Autor:
Bethany Moore, Hui Feng, Itrat Harrold, Gina Nguyen, Amandeep S. Saini, John P. Kanki, Cicely A. Jette, Nicole M. Anderson, Seth Carbonneau
Publikováno v:
BioTechniques. 60:13-20
The zebrafish represents a revolutionary tool in large-scale genetic and small-molecule screens for gene and drug discovery. Transgenic zebrafish are often utilized in these screens. Many transgenic fish lines are maintained in the heterozygous state
Autor:
Harold Truong, Michelle Gulfo, Rosannah C. Cameron, Shelly Sorrells, Sara Nik, Rodney A. Stewart, Cicely A. Jette, Teresa V. Bowman, Mattie J. Casey, Cristhian Toruno, Albert Lowe
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 2 (2018)
Disease Models & Mechanisms
Disease Models & Mechanisms
RNA splicing factors are essential for the viability of all eukaryotic cells; however, in metazoans some cell types are exquisitely sensitive to disruption of splicing factors. Neuronal cells represent one such cell type, and defects in RNA splicing