Výsledky vyhledávání - "Ciardiello JJ"

Concise synthesis of rare pyrido[1,2-a]pyrimidin-2-ones and related nitrogen-rich bicyclic scaffolds with a ring-junction nitrogen

Autor: Alanine, TA, Galloway, WRJD, Bartlett, S, Ciardiello, JJ, McGuire, TM, Spring, DR

Pyrido[1,2-a]pyrimidin-2-ones represent a pharmaceutically interesting class of heterocycles. The structurally related pyrido[1,2-a]pyrimidin-4-ones are associated with a broad range of useful biological properties. Furthermore, quinolizinone-type sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______109::0bab6f27d7d54d8381e1682d9190696c
https://www.repository.cam.ac.uk/handle/1810/253003

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An expedient strategy for the diversity-oriented synthesis of macrocyclic compounds with natural product-like characteristics

Autor: Ciardiello, JJ, Galloway, WRJD, O'Connor, CJ, Sore, HF, Stokes, JE, Wu, Y, Spring, DR

Publikováno v: Tetrahedron. (25):3567-3578

Naturally-derived macrocyclic compounds are associated with a diverse range of biological activities, including antibacterial effects, and there are over 100 marketed macrocycle drugs derived from natural products. However, synthetic macrocycles are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5c7ca8d90db26a0a4370c8b58bf79b53

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Akademický článek

A novel complexity-to-diversity strategy for the diversity-oriented synthesis of structurally diverse and complex macrocycles from quinine.

Autor: Ciardiello JJ; Department of Chemistry, The University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Stewart HL; Department of Chemistry, The University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Sore HF; Department of Chemistry, The University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Galloway WRJD; Department of Chemistry, The University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom., Spring DR; Department of Chemistry, The University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom. Electronic address: spring@ch.cam.ac.uk.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2017 Jun 01; Vol. 25 (11), pp. 2825-2843. Date of Electronic Publication: 2017 Feb 28.

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Akademický článek

Stereocontrolled semi-syntheses of deguelin and tephrosin.

Autor: Russell DA; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Freudenreich JJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Ciardiello JJ; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Sore HF; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Spring DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2017 Feb 21; Vol. 15 (7), pp. 1593-1596. Date of Electronic Publication: 2017 Jan 30.

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Akademický článek

Concise synthesis of rare pyrido[1,2-a]pyrimidin-2-ones and related nitrogen-rich bicyclic scaffolds with a ring-junction nitrogen.

Autor: Alanine TA; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Galloway WR, Bartlett S, Ciardiello JJ, McGuire TM, Spring DR

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2016 Jan 21; Vol. 14 (3), pp. 1031-8. Date of Electronic Publication: 2015 Dec 03.

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