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pro vyhledávání: '"Ciaran Mcginn"'
Autor:
Brian F. MacDonnell, Chun Xu Shan, Robert G. Wallace, Philip M. Cummins, Ciaran Mcginn, Ronan P. Murphy
Publikováno v:
Current Clinical Pharmacology. 11:28-42
Microvesicles (MVs) are submicron intact particles released from the cellular membrane of eukaryotic cells. MVs can be sub-categorised into microparticles (MPs), which are between 100nm- 1micron in size, and exosomes, measuring less than 100nm. Once
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Endothelial integrity plays a pivotal role in normal blood vessel function and disruption of which will lead to the initiation and progression of atherosclerosis. The actin cytoskeleton which provides endothelial structural integrity can be greatly d
Autor:
Ciaran Mcginn, Paul Fitzpatrick, Shan Chunxu, Andrew Murphy, Brian MacDonnell, Paul Dowling, Philip Cummins, Ronan Murphy
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Palladin, an actin filament associated protein, plays an important role in cell cytoskeletal regulation, with particular regards to the formation and stablilization of stress fibres. The protein is part of the myotilin-myopalladin-palladin family, bu