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of 5
pro vyhledávání: '"Ciara Whitty"'
Autor:
Ciara Whitty, Christian Pernstich, Charlotte Marris, Andrew McCaskie, Michael Jones, Frances Henson
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 1, Pp 100240- (2022)
Objective: Attempts to utilise growth factors (GF) such as bone morphogenic proteins (BMPs) to treat osteoarthritis (OA) in the clinic have not secured widespread adoption. However, the novel crystalline GF formulation called PODS offers new perspect
Externí odkaz:
https://doaj.org/article/712a594bd389472f8e8230903c42a495
Autor:
Yuka Matsuzaki, Rina Maruta, Keiko Takaki, Eiji Kotani, Yasuko Kato, Ryoichi Yoshimura, Yasuhisa Endo, Ciara Whitty, Christian Pernstich, Raj Gandhi, Michael Jones, Hajime Mori
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 510 (2019)
The spatial and temporal availability of cytokines, and the microenvironments this creates, is critical to tissue development and homeostasis. Creating concentration gradients in vitro using soluble proteins is challenging as they do not provide a se
Externí odkaz:
https://doaj.org/article/2163037a146d44baa5ede03fb9200469
Autor:
Yasuhisa Endo, Keiko Takaki, Raj Gandhi, Eiji Kotani, Ryoichi Yoshimura, Yasuko Kato, Rina Maruta, Matsuzaki Yuka, Christian Pernstich, Michael Jones, Hajime Mori, Ciara Whitty
Publikováno v:
Biomolecules
Biomolecules, Vol 9, Iss 10, p 510 (2019)
Volume 9
Issue 10
Biomolecules, Vol 9, Iss 10, p 510 (2019)
Volume 9
Issue 10
The spatial and temporal availability of cytokines, and the microenvironments this creates, is critical to tissue development and homeostasis. Creating concentration gradients in vitro using soluble proteins is challenging as they do not provide a se
Publikováno v:
Biochemical and biophysical research communications. 503(2)
Sclerostin is a clinically important protein with key functions in the musculoskeletal system playing a key role in bone formation and remodelling. Whilst a wide range of mechanisms have been identified which regulate sclerostin expression, little is
Publikováno v:
Biochemical and biophysical research communications. 446(4)
Sclerostin is widely reported to be a monomeric osteocyte specific protein. In this study we have investigated whether sclerostin is produced in different forms and in which cell and tissue types they are produced. We have demonstrated that recombina