Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika

Autor: Paulina Andrade, Ciara Gimblet-Ochieng, Faraz Modirian, Matthew Collins, Maritza Cárdenas, Leah C. Katzelnick, Magelda Montoya, Daniela Michlmayr, Guillermina Kuan, Angel Balmaseda, Josefina Coloma, Aravinda M. de Silva, Eva Harris

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Here, Andrade et al. assess the memory B cell (MBC) and antibody response to Zika virus (ZIKV) in individuals with and without prior dengue virus (DENV) infection and find that ZIKV infection elicits a robust and specific MBC response that is only mo

Externí odkaz: https://doaj.org/article/c554c8c491bc4839a274cc4a0886664d

Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika

Autor: Angel Balmaseda, Guillermina Kuan, Ciara Gimblet-Ochieng, Matthew H. Collins, Eva Harris, Maritza Cárdenas, Josefina Coloma, Faraz Modirian, Aravinda M. de Silva, Leah C. Katzelnick, Paulina Andrade, Daniela Michlmayr, Magelda Montoya

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, vol 10, iss 1

Little is known about enduring memory B cell (MBC) responses to Zika virus (ZIKV) and their relationship with circulating antibodies. Here we comprehensively assess MBC frequency and specificity alongside serum binding and neutralizing antibody respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d5a6ccd119dd695b2d5667872c4f5c
https://doi.org/10.1038/s41467-019-08845-3