Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ciarán P Kelly"'
Autor:
Chandrabali Ghose, Ioannis Eugenis, Xingmin Sun, Adrianne N Edwards, Shonna M McBride, David T Pride, Ciarán P Kelly, David D Ho
Publikováno v:
Emerging Microbes and Infections, Vol 5, Iss 1, Pp 1-10 (2016)
Clostridium difficile is a Gram-positive bacillus and is the leading cause of toxin-mediated nosocomial diarrhea following antibiotic use. C. difficile flagella play a role in colonization, adherence, biofilm formation, and toxin production, which mi
Externí odkaz:
https://doaj.org/article/d0e936a456e247679c534d25c18890a9
Autor:
Mária Džunková, Giuseppe D'Auria, Hua Xu, Jun Huang, Yinghua Duan, Andres Moya, Ciarán P Kelly, Xinhua Chen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Antibiotics have significant and long-lasting impacts on the intestinal microbiota and consequently reduce colonization resistance against Clostridium difficile infection (CDI). Standard therapy using antibiotics is associated with a high rate of dis
Externí odkaz:
https://doaj.org/article/06f9bebc1a3b4a8991c00911d4515d26
Autor:
Erik R Dubberke, Margaret A Olsen, Dustin Stwalley, Ciarán P Kelly, Dale N Gerding, Yinong Young-Xu, Cedric Mahé
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0146822 (2016)
Population attributable risk percent (PAR%) is an epidemiological tool that provides an estimate of the percent reduction in total disease burden if that disease could be entirely eliminated among a subpopulation. As such, PAR% is used to efficiently
Externí odkaz:
https://doaj.org/article/66c5723bcd0d447bbaabfd7dbabc8cf9
Autor:
Xi Na, Alan J Martin, Saurabh Sethi, Lorraine Kyne, Kevin W Garey, Sarah W Flores, Mary Hu, Dhara N Shah, Kelsey Shields, Daniel A Leffler, Ciarán P Kelly
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123405 (2015)
Prediction of severe clinical outcomes in Clostridium difficile infection (CDI) is important to inform management decisions for optimum patient care. Currently, treatment recommendations for CDI vary based on disease severity but validated methods to
Externí odkaz:
https://doaj.org/article/7c5f038e832d4ba1b914b647ef692982
Autor:
Lena Novack, Slava Kogan, Larisa Gimpelevich, Michael Howell, Abraham Borer, Ciarán P Kelly, Daniel A Leffler, Victor Novack
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110790 (2014)
OBJECTIVE: An adverse effect of acid-suppression medications on the occurrence of Clostridium difficile infection (CDI) has been a common finding of many, but not all studies. We hypothesized that association between acid-suppression medications and
Externí odkaz:
https://doaj.org/article/1f4e9c7dda374ce89f8646796533e330
Autor:
Thomas J. Sandora, Larry K. Kociolek, David N. Williams, Kaitlyn Daugherty, Christine Geer, Christine Cuddemi, Xinhua Chen, Hua Xu, Timothy J. Savage, Alice Banz, Kevin W. Garey, Anne J. Gonzales-Luna, Ciarán P. Kelly, Nira R. Pollock
Publikováno v:
Infection Control & Hospital Epidemiology. :1-7
Background: In adults with Clostridioides difficile infection (CDI), higher stool concentrations of toxins A and B are associated with severe baseline disease, CDI-attributable severe outcomes, and recurrence. We evaluated whether toxin concentration
Autor:
Giovanni A. Roldan, Daniela Goyes, Javier A. Villafuerte-Gálvez, Mariana Urquiaga, Melinda Dennis, Joseph A. Murray, Daniel A. Leffler, Ciarán P. Kelly
Publikováno v:
American Journal of Gastroenterology. 117:1684-1692
Autor:
Carolyn D Alonso, Nira R Pollock, Kevin W Garey, Anne J Gonzales-Luna, David N Williams, Kaitlyn Daugherty, Christine Cuddemi, Javier Villafuerte-Gálvez, Nicole C White, Xinhua Chen, Hua Xu, Rebecca Sprague, Caitlin Barrett, Mark Miller, Agnès Foussadier, Aude Lantz, Alice Banz, Ciarán P Kelly
Publikováno v:
Clin Infect Dis
Ultrasensitive, quantitative Clostridioides difficile stool toxin measurement demonstrated significantly higher concentrations of toxins A and B in patients infected with the North American pulsed-field gel electrophoresis type 1/ribotype 027 (NAP-1/
Autor:
Marcela Banegas, Javier Villafuerte-Gálvez, Rodrigo Paredes, Rebecca Sprague, Caitlin Barrett, Anne J Gonzales-Luna, Kaitlyn Daugherty, Kevin W Garey, Hua Xu, Qianyun Lin, Lamei Wang, Xinhua Chen, Nira R Pollock, Ciarán P Kelly, Carolyn D Alonso
Publikováno v:
Open Forum Infectious Diseases. 10
BackgroundClostridioides difficile infection (CDI) immune response is influenced by the innate and adaptive (humoral) immune systems. Our prior research found attenuated humoral responses to C difficile in immunocompromised hosts (ICHs) with CDI. We
Publikováno v:
Yamada's Textbook of Gastroenterology. :1122-1136