Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cian Glenfield"'
Autor:
Anthony Letai, Michelle A. Kelliher, Alejandro Gutierrez, Marian Harris, Richard Stone, Daniel J. DeAngelo, Brent Wood, Stephen P. Hunger, Mignon L. Loh, Lewis B. Silverman, Stephen E. Sallan, Jeremy Ryan, Cian Glenfield, Justine E. Roderick, Triona Ni Chonghaile
NSG mice were injected in the tail with either ETP-ALL (TALL-x-11) or typical T-ALL (TALL-x-2) 1X106 cells and following engraftment to 65% the mice were randomized to receive vehicle, ABT-199 or ABT-263 treatment for two-weeks. The spleen weights (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420fd463af5ed6dbbe884834272bae70
https://doi.org/10.1158/2159-8290.22531948.v1
https://doi.org/10.1158/2159-8290.22531948.v1
Autor:
Hideki Innan, Cian Glenfield
Publikováno v:
Genes
Genes, Vol 12, Iss 1376, p 1376 (2021)
Genes, Vol 12, Iss 1376, p 1376 (2021)
Chromosomal rearrangement and genome instability are common features of cancer cells in human. Consequently, gene duplication and gene fusion events are frequently observed in human malignancies and many of the products of these events are pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7b71094f6ece48b447cb55439ec167
http://europepmc.org/articles/PMC8466788
http://europepmc.org/articles/PMC8466788
Autor:
Aoife McLysaght, Cian Glenfield
Publikováno v:
Molecular Biology and Evolution
The competitive endogenous RNA (ceRNA) hypothesis is an attractively simple model to explain the biological role of many putatively functionless noncoding RNAs. Under this model, there exist transcripts in the cell whose role is to titrate out microR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11adc9331f6154199ed1e87ae0b6b8fb
http://europepmc.org/articles/PMC6278865
http://europepmc.org/articles/PMC6278865
Autor:
Mignon L. Loh, Lewis B. Silverman, Michelle A. Kelliher, Daniel J. DeAngelo, Brent L. Wood, Richard Stone, Triona Ni Chonghaile, Cian Glenfield, Marian H. Harris, Justine E. Roderick, Anthony Letai, Jeremy Ryan, Stephen P. Hunger, Stephen E. Sallan, Alejandro Gutierrez
Publikováno v:
Cancer Discovery. 4:1074-1087
Acute lymphoblastic leukemia (ALL) is a hematopoietic malignancy derived from immature B-lymphoid and T-lymphoid cells (T-ALL). In T-ALL, there is an early T-cell progenitor (ETP) subgroup that has a very high risk for relapse. In this study, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1347ac04d0a913c3f9612c330a28894a
https://doi.org/10.1158/2159-8290.cd-14-0353
https://doi.org/10.1158/2159-8290.cd-14-0353
Autor:
Glenfield, Cian, McLysaght, Aoife
Publikováno v:
Molecular Biology & Evolution; Dec2018, Vol. 35 Issue 12, p2886-2899, 14p