Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Cian O'Donnell"'
Autor:
Hanna K. Isotalus, Will J. Carr, Jonathan Blackman, George G. Averill, Oliver Radtke, James Selwood, Rachel Williams, Elizabeth Ford, Liz McCullagh, James McErlane, Cian O'Donnell, Claire Durant, Ullrich Bartsch, Matt W. Jones, Carlos Muñoz-Neira, Alfie R. Wearn, John P. Grogan, Elizabeth J. Coulthard
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/e25d794abcbf4d9e9c248174ffc45c47
Publikováno v:
eLife, Vol 12 (2024)
Biological synaptic transmission is unreliable, and this unreliability likely degrades neural circuit performance. While there are biophysical mechanisms that can increase reliability, for instance by increasing vesicle release probability, these mec
Externí odkaz:
https://doaj.org/article/08dbd6104404401eaf5e610ced0ffb47
Publikováno v:
eLife, Vol 12 (2023)
Electroencephalography and magnetoencephalography recordings are non-invasive and temporally precise, making them invaluable tools in the investigation of neural responses in humans. However, these recordings are noisy, both because the neuronal elec
Externí odkaz:
https://doaj.org/article/2c9ee025b8524fb1916b44f3083e1948
Autor:
Thomas J. Delaney, Cian O’Donnell
Publikováno v:
Network Neuroscience, Vol 7, Iss 2, Pp 731-742 (2023)
AbstractEnsembles of neurons are thought to be coactive when participating in brain computations. However, it is unclear what principles determine whether an ensemble remains localised within a single brain region, or spans multiple brain regions. To
Externí odkaz:
https://doaj.org/article/ad0b3e72338c4d858dfebc359d30c2b8
Publikováno v:
eLife, Vol 12 (2023)
Discovering the rules of synaptic plasticity is an important step for understanding brain learning. Existing plasticity models are either (1) top-down and interpretable, but not flexible enough to account for experimental data, or (2) bottom-up and b
Externí odkaz:
https://doaj.org/article/a333dbddecff47a99c9637ccf9172bd0
Autor:
Hanna K. Isotalus, Will J. Carr, Jonathan Blackman, George G. Averill, Oliver Radtke, James Selwood, Rachel Williams, Elizabeth Ford, Liz McCullagh, James McErlane, Cian O’Donnell, Claire Durant, Ullrich Bartsch, Matt W. Jones, Carlos Muñoz-Neira, Alfie R. Wearn, John P. Grogan, Elizabeth J. Coulthard
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionMillions of people worldwide take medications such as L-DOPA that increase dopamine to treat Parkinson’s disease. Yet, we do not fully understand how L-DOPA affects sleep and memory. Our earlier research in Parkinson’s disease reveale
Externí odkaz:
https://doaj.org/article/fa9400a7bf344e249cb23767672f078d
Publikováno v:
Neuroscience. 489:69-83
Acetylcholine has been proposed to facilitate the formation of memory ensembles within the hippocampal CA3 network, by enhancing plasticity at CA3-CA3 recurrent synapses. Regenerative NMDA receptor (NMDAR) activation in CA3 neuron dendrites (NMDA spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb62376e96a7f23ff51ac8c2987ad7c8
https://doi.org/10.1016/j.neuroscience.2021.11.014
https://doi.org/10.1016/j.neuroscience.2021.11.014
Autor:
Rahul Gupta, Cian O’Donnell
Dendritic spines host glutamatergic excitatory synapses and compartmentalize biochemical signalling underlying synaptic plasticity. The narrow spine neck that connects the spine head with its parent dendrite is the crucial structural element of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f8c459010fa8f512d19b3c7544df78
https://doi.org/10.1101/2023.01.27.525952
https://doi.org/10.1101/2023.01.27.525952
Electroencephalography and magnetoencephalography recordings are non-invasive and temporally precise, making them invaluable tools in the investigation of neural responses in humans. However, these recordings are noisy, both because the neuronal elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efcf3ba75b93d1dbe9d5a8a04949fa94
https://doi.org/10.31234/osf.io/2vcsy
https://doi.org/10.31234/osf.io/2vcsy
Publikováno v:
eLife, Vol 6 (2017)
A leading theory holds that neurodevelopmental brain disorders arise from imbalances in excitatory and inhibitory (E/I) brain circuitry. However, it is unclear whether this one-dimensional model is rich enough to capture the multiple neural circuit a
Externí odkaz:
https://doaj.org/article/43f3ac1210e8404a89a511998e25af56