Zobrazeno 1 - 10 of 596 pro vyhledávání: '"Ciências Biológicas [Ciências Naturais]"'
1
Anti-EFG1 2′-OMethylRNA oligomer inhibits Candida albicans filamentation and attenuates the candidiasis in Galleria mellonella
Autor: Mariana Henriques, Dalila Mil-Homens, Daniela Araújo, Sónia Silva
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 27, Iss, Pp 517-523 (2022)
Molecular Therapy. Nucleic Acids
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
EFG1 is a central transcriptional regulator of filamentation that is an important virulence factor of Candida albicans. This study serves to assess in vivo the applicability of the anti-EFG1 2-OMethylRNA oligomer for inhibiting Candida albicans filam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8ec732ce2e08545126fdcdd6cd483e
http://www.sciencedirect.com/science/article/pii/S2162253121003218
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2
Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity
Autor: Victória Soares Soeiro, Ricardo Silva-Carvalho, Daniela Martins, Pier Parpot, Denise Grotto, Marco Vinicius Chaud, Francisco Miguel Portela da Gama, Angela Faustino Jozala
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports
Nanocomplexes systems made up natural poylymers have pharmacotechnical advantages such as increase of water solubility and a decrease of drugs toxicity. Amphotericin B (AmB) is a drug apply as anti-leishmanial and anti-fungal, however it has low wate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e171c30c9f10f597faed7d6ebaa1698
https://doaj.org/article/5b614528feef404cbe2e25ffeac49579
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3
Magnetoliposomes: recent advances in the field of controlled drug delivery
Autor: Raquel G. D. Andrade, Elisabete M. S. Castanheira, Sérgio Rafael Silva Veloso
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Magnetoliposomes have gained increasing attention as delivery systems, as they surpass many limitations associated with liposomes. The combination with magnetic nanoparticles provides a means for development of multimodal and multifunctional theranos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142d11dc99fc5d4ba47510fa8ba2df5d
https://doi.org/10.1080/17425247.2021.1915983
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4
Polymeric micelles using cholinium-based ionic liquids for the encapsulation and release of hydrophobic drug molecules
Autor: Daniel T. Kamei, Isabelle S. Kurnik, Marlus Chorilli, Natália A. D'Angelo, André Moreni Lopes, António A. Vicente, Jorge F. B. Pereira, Priscila Gava Mazzola
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
We generated stable amphiphilic copolymer-based polymeric micelles (PMs) with temperature-responsive properties utilizing Pluronic® L35 and a variety of ionic liquids (ILs) to generate different aqueous two-phase micellar systems (ATPMSs). The parti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5ce3a62ea77eb70156628aaab858da
https://doi.org/10.1039/d0bm01884h
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5
Valorisation of rejected unripe plantain fruits of Musa AAB Simmonds: from nutritional characterisation to the conceptual process design for prebiotic production
Autor: Luis G. Matallana, Clarisse Nobre, José A. Teixeira, Óscar J. Sánchez, Enrique Pino-Hernández, James A. Gómez, Luís Abrunhosa
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The increasing consumption of plantain fruits with specific quality standards generates high agricultural waste. This work aimed at valorising the rejected unripe pulp of Dominico-Hartón plantain fruits (Musa AAB Simmonds). The pulp was characterise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1152c0fb483d00f0264b2181ce95b68
https://doi.org/10.1039/d0fo03379k
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6
Chlorinated cyanurates and potassium salt of peroxymonosulphate as antimicrobial and antibiofilm agents for drinking water disinfection
Autor: Oliveira, Isabel Maria, Gomes, Inês B., Simões, Lúcia Chaves, Simões, Manuel Lopes
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The understanding of microbial susceptibility to disinfectants is an important step to provide drinking water (DW) of adequate microbiological quality. In drinking water distribution systems (DWDS) the application of disinfectants is the main approac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f461c1fc74a04b3752cb4cbe0b440f
https://hdl.handle.net/1822/75271
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7
Hydrothermal and high-pressure processing of chestnuts - Dependence on the storage conditions
Autor: Carlos Pinto, José Teixeira, Luís Abrunhosa, Enrique Pino Hernández, Jorge Saraiva
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
High-pressure processing (HPP) is an emergent technology for nonthermal pasteurization of foods, which here demonstrates the potential to be used by the chestnut industry. This study evaluated HPP as a post-harvest processing technology to control mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc546ddc762e59cd9d27e038fe61fb4
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8
Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process
Autor: Manuela Côrte-Real, Filipa Mendes, Leslie Ann Silva Amaral, Maria João Sousa, Susana R. Chaves
Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cisplatin is a widely used antineoplastic agent that has DNA as the main target, though cellular resistance hampers its therapeutic efficacy. An emerging hallmark of cancer cells is their altered metabolism, characterized by increased glycolysis even
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5364b04042b19214cac9f6e1283c8d31
https://doi.org/10.1155/2020/4971525
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9
First ecotoxicological characterization of paraffin microparticles: a biomarker approach in a marine suspension-feeder, Mytilus sp
Autor: Bruno Nunes, Juan Carlos Navarro, Bruno B. Castro, Maria Inês Simões
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Microplastics are one of the main environmental pollutants in marine ecosystems, and their presence in seawater is a consequence of the widespread use of plastic materials in modern commodities. This wide usage of plastics includes the employment of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0362e38e963e0072b2354d7aa096a7a0
https://doi.org/10.1007/s11356-020-10055-0
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10
Hepatoprotective effect of Phellinus linteus mycelia polysaccharide (PL-N1) against acetaminophen-induced liver injury in mouse
Autor: Alberto Carlos Pires Dias, Chen Chen, Xiaoying Zhang, Shanshan Qi, Xiang Liu, Jing-Kun Yan
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Edible and medicinal fungi are one of the major sources for extraction and identification of polysaccharides, which are important biological response modifiers with notable antitumor, hepatoprotective effect and other pharmacological activities. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036cccbb3134573c51d90b0e4dbd5205
https://doi.org/10.1016/j.ijbiomac.2019.11.002
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