Resistance to the Non-Covalent BTK Inhibitor Pirtobrutinib

Autor: Aishath S Naeem, Filippo Utro, Qing Wang, Justin Cha, Mauno Vihinen, Stephen P. Martindale, Yinglu Zhou, Svitlana Tyekucheva, Annette S. Kim, Stacey M. Fernandes, Rayan Fardoun, Gordon Saksena, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P Danysh, Kara Slowik, Raquel Jacobs, Matthew S. Davids, Rula Zain, Edvard CI Smith, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown

Publikováno v: Blood. 140:6981-6982

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93ab0ebe021733364478d3d833fae0c3
https://doi.org/10.1182/blood-2022-160279

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase

Autor: Salim K, Mj, Bottomley, Querfurth E, Marketa Zvelebil, Gout I, Scaife R, Rl, Margolis, Gigg R, Ci, Smith, Pc, Driscoll, Md, Waterfield, Panayotou G

Publikováno v: Europe PubMed Central

Pleckstrin homology (PH) domains may act as membrane localization modules through specific interactions with phosphoinositide phospholipids. These interactions could represent responses to second messengers, with scope for regulation by soluble inosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2559fbeede1e6403e8bfe1fdf9b3f43d
https://pubmed.ncbi.nlm.nih.gov/8947047

Detection of IgA heavy chain constant region genes in IgA deficient donors: evidence against gene deletions

Autor: Hammarström L, Carlsson B, Ci, Smith, Wallin J, Lars Wieslander

Publikováno v: Europe PubMed Central

Sixty-six donors with selective IgA deficiency and one patient with selective IgA2 deficiency were investigated for immunoglobulin gene defects using restriction enzyme digestions and Southern blot analysis. All patients carried alpha 1 and alpha 2 g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::15de0344d96fcd70472082395b3430c2
http://europepmc.org/abstract/med/2990782

Isolation of cDNA clones mapping around DXS178: a search for human X-linked agammaglobulinaemia gene using yeast artificial chromosomes, cosmids and direct cDNA selection

Autor: Vorechovský I, Holland J, Sideras P, Dunham I, Hammarström L, Ci, Smith, Dr, Bentley, David Vetrie

Publikováno v: Europe PubMed Central

X-linked agammaglobulinaemia (XLA) was previously mapped using genetic linkage analysis to Xq22. No recombinants have been found so far between the XLA locus and DXS178 in over 30 informative meioses. Two overlapping yeast artificial chromosomes (YAC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b3062569151cbc0dc3fb1cf345b5a63
http://europepmc.org/abstract/med/8167705

An optical photothermal infrared investigation of lymph nodal metastases of oral squamous cell carcinoma.

Autor: Al Jedani S; Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK.; Department of Physics, University of Jeddah, Jeddah, Saudi Arabia., Lima C; Centre for Metabolomics Research, Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK., Smith CI; Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK., Gunning PJ; Department of Molecular and Clinical Cancer Medicine, Liverpool Head and Neck Centre, University of Liverpool, Liverpool, L7 8TX, UK., Shaw RJ; Department of Molecular and Clinical Cancer Medicine, Liverpool Head and Neck Centre, University of Liverpool, Liverpool, L7 8TX, UK.; Head and Neck Surgery, Liverpool University Foundation NHS Trust, Aintree Hospital, Liverpool, L9 7AL, UK., Barrett SD; Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK., Triantafyllou A; Department of Cellular Pathology, Liverpool Clinical Laboratories, University of Liverpool, Liverpool, L7 8YE, UK., Risk JM; Department of Molecular and Clinical Cancer Medicine, Liverpool Head and Neck Centre, University of Liverpool, Liverpool, L7 8TX, UK., Goodacre R; Centre for Metabolomics Research, Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK., Weightman P; Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 7ZE, UK. peterw@liverpool.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2024 Jul 11; Vol. 14 (1), pp. 16050. Date of Electronic Publication: 2024 Jul 11.