Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Chyung Ru Wang"'
Autor:
Eva Morgun, Jennifer Zhu, Sultan Almunif, Sharan Bobbala, Melissa S Aguilar, Junzhong Wang, Kathleen Conner, Yongyong Cui, Liang Cao, Chetan Seshadri, Evan A Scott, Chyung-Ru Wang
Publikováno v:
eLife, Vol 12 (2023)
Mycobacterium tuberculosis (Mtb) infection elicits both protein and lipid antigen-specific T cell responses. However, the incorporation of lipid antigens into subunit vaccine strategies and formulations has been underexplored, and the characteristics
Externí odkaz:
https://doaj.org/article/6b58467588cc497ca1e3645a884385c2
Autor:
Samantha Genardi, Lavanya Visvabharathy, Liang Cao, Eva Morgun, Yongyong Cui, Chao Qi, Yi-Hua Chen, Laurent Gapin, Evgeny Berdyshev, Chyung-Ru Wang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Methicillin-resistant Staphylococcus aureus (SA) bacteremia is responsible for over 10,000 deaths in the hospital setting each year. Both conventional CD4+ T cells and γδ T cells play protective roles in SA infection through secretion of IFN-γ and
Externí odkaz:
https://doaj.org/article/4738979384d84047be2f0c52342e0eee
Autor:
Lavanya Visvabharathy, Samantha Genardi, Liang Cao, Ying He, Francis Alonzo, Evgeny Berdyshev, Chyung-Ru Wang
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008443 (2020)
Staphylococcus aureus (SA) is the causative agent of both skin/soft tissue infections as well as invasive bloodstream infections. Though vaccines have been developed to target both humoral and T cell-mediated immune responses against SA, they have la
Externí odkaz:
https://doaj.org/article/b57ecb31b2ca48d48fc36cf068858a2f
Autor:
Yajun Wang, Chawon Yun, Beixue Gao, Yuanming Xu, Yana Zhang, Yiming Wang, Qingfei Kong, Fang Zhao, Chyung-Ru Wang, Sharon Y.R. Dent, Jian Wang, Xiangping Xu, Hua-Bin Li, Deyu Fang
Publikováno v:
Cell Reports, Vol 20, Iss 3, Pp 600-612 (2017)
The development of CD1d-restricted invariant natural killer T (iNKT) cells, a population that is critical for both innate and adaptive immunity, is regulated by multiple transcription factors, but the molecular mechanisms underlying how the transcrip
Externí odkaz:
https://doaj.org/article/cf497dfbc3034317b129cd83f1a95834
Autor:
Shaobin Shang, Dina Kats, Liang Cao, Eva Morgun, Diana Velluto, Ying He, Qichen Xu, Chyung-Ru Wang, Evan A. Scott
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mycolic acid (MA), a major lipid component of Mycobacterium tuberculosis (Mtb) cell wall, can be presented by the non-polymorphic antigen presenting molecule CD1b to T cells isolated from Mtb-infected individuals. These MA-specific CD1b-restricted T
Externí odkaz:
https://doaj.org/article/734e8337d93c48bc937436e270992b86
Publikováno v:
J Invest Dermatol
Autoimmunity results from the breaking of immune tolerance, leading to inflammation and pathology. Although well studied in the conventional T-cell field, the role of nonconventional T cells in autoimmunity is less understood. CD1-restricted T cells
Autor:
Morgun, Eva, Zhu, Jennifer, Almunif, Sultan, Bobbala, Sharan, Aguilar, Melissa S., Junzhong Wang, Conner, Kathleen, Yongyong Cui, Liang Cao, Seshadri, Chetan, Scott, Evan A., Chyung-Ru Wang
Publikováno v:
eLife; 10/25/2023, p1-23, 23p
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Dyslipidemia, or altered blood lipid content, is a risk factor for developing cardiovascular disease. Furthermore, several autoimmune diseases, including systemic lupus erythematosus, psoriasis, diabetes, and rheumatoid arthritis, are correlated high
Externí odkaz:
https://doaj.org/article/caa2dbd0a57346a8aad66c6b3ea3160d
Autor:
Yao Bian, Shaobin Shang, Sarah Siddiqui, Jie Zhao, Simone A Joosten, Tom H M Ottenhoff, Harvey Cantor, Chyung-Ru Wang
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006384 (2017)
A number of nonclassical MHC Ib molecules recognizing distinct microbial antigens have been implicated in the immune response to Mycobacterium tuberculosis (Mtb). HLA-E has been identified to present numerous Mtb peptides to CD8+ T cells, with multip
Externí odkaz:
https://doaj.org/article/48a6259999804211b01cd5414104259c