Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Chyung Cook"'
1
Daily peritoneal administration of sodium pyrophosphate in a dialysis solution prevents the development of vascular calcification in a mouse model of uraemia
Autor: Loïc Louvet, Raja Rezg, Bruce L. Riser, Jeff White, Fellype C. Barreto, Jerome H. Gass, Chyung Cook, Tilman B. Drüeke, Ziad A. Massy, Paul W. Valaitis, Julien Maizel, Clifford J. Holmes
Publikováno v: Nephrology Dialysis Transplantation. 26:3349-3357
Background The high rate of cardiovascular mortality in patients with end-stage renal disease (ESRD) is a significant barrier to improved life expectancy. Unique in this population is the marked development and aggressive worsening of vascular calcif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5376439f3ec56cbabe543fbf8868dd78
https://doi.org/10.1093/ndt/gfr039
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2
Nanosuspension Formulation of Itraconazole Eliminates the Negative Inotropic Effect of SPORANOX® in Dogs
Autor: Jeff McKee, Barrett E. Rabinow, Jerry Gass, Chyung Cook
Publikováno v: Journal of Medical Toxicology. 6:331-336
Previously, it was observed that a nanosuspension formulation of itraconazole was more efficacious and yet less acutely toxic in rats as compared with the conventional solution formulation, SPORANOX® (itraconazole) Injection. The present study compa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a20a3cf8c95e36132fc3225a18245b4
https://doi.org/10.1007/s13181-010-0025-6
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3
PROMAXX®inhaled insulin: safe and efficacious administration with a commercially available dry powder inhaler
Autor: U Eckers, J. Troeger, A. Brugger, Paul W. Valaitis, Tim Heise, Chyung Cook, S. White, Leszek Nosek, K. Rave, Lutz Heinemann, A. Hutchcraft
Publikováno v: Diabetes, Obesity and Metabolism. 11:455-459
OBJECTIVES We investigated the pharmacokinetic (PK) and pharmacodynamic (PD) properties of recombinant human insulin inhalation powder (RHIIP), manufactured with PROMAXX technology, which allows formation of uniform protein microspheres. METHODS Thir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffaaa60fb273c5b29570b8f9106ff9c
https://doi.org/10.1111/j.1463-1326.2008.00961.x
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4
Differences in Relative Bioavailability (BA) of Inhalation Insulin Determined using Insulin and Glucose Levels Following Subcutaneous and Inhalation Administration in Humans
Autor: Paul W. Valaitis, Lutz Heinemann, Laura Anderson, Steve White, Leszek Nosek, Janice Troeger, Tim Heise, Jerry Gass, Chyung Cook, Klause Rave, Uta Eckers, Andrew Brugger
Publikováno v: Journal of Bioequivalence & Bioavailability.
BA may be determined using both plasma concentrations of a drug (pharmacokinetic parameters) and its pharmacological effects (pharmacodynamic parameters). However, the resulting assessments of BA can be substantially different. In a relative BA study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cdf8d5c55f7d3c600da18c6579fd0d0
https://doi.org/10.4172/jbb.1000085
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5
Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat
Autor: Kristy Wood, Kerry Barker, Chyung Cook, Pavlos Papadopoulos, Jerome H. Gass, Barrett E. Rabinow, Randy D. White, Todd Wielgos, Chong-Son Sun, Jill Glosson, Joseph Chung Tak Wong, James E. Kipp
Publikováno v: International journal of pharmaceutics. 339(1-2)
The goal of this research was to evaluate an intravenous itraconazole nanosuspension dosage form, relative to a solution formulation, in the rat. Itraconazole was formulated as a nanosuspension by a tandem process of microcrystallization followed by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aba28fdb644fec83c0d98bf9459f61d
https://pubmed.ncbi.nlm.nih.gov/17398045
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