Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Chwen Lih Chen"'
Autor:
Feng Dong, Liya Yin, Hamayak Sisakian, Tatevik Hakobyan, Lacey S Jeong, Hirva Joshi, Ellianna Hoff, Selena Chandler, Geetika Srivastava, Abdur Rahman Jabir, Kelly Kimball, Yeong-Renn Chen, Chwen-Lih Chen, Patrick T Kang, Parisa Shabani, Lindsay Shockling, Thomas Pucci, Karlina Kegecik, Christopher Kolz, Zhenyu Jia, William M Chilian, Vahagn Ohanyan
Publikováno v:
European Heart Journal.
Background and aims Takotsubo syndrome (TTS) is a conundrum without consensus about the cause. In a murine model of coronary microvascular dysfunction (CMD), abnormalities in myocardial perfusion played a key role in the development of TTS. Methods a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a33142c050a186fba7b72dda7927a6de
https://doi.org/10.1093/eurheartj/ehad274
https://doi.org/10.1093/eurheartj/ehad274
Publikováno v:
Am J Physiol Cell Physiol
Mitochondrial reactive oxygen species (ROS) have emerged as an important mechanism of disease and redox signaling in the cellular system. Under basal or pathological conditions, electron leakage for ROS production is primarily mediated by complexes I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b9a0b75d778f2d59dfc89bd2b92b6f
https://doi.org/10.1152/ajpcell.00131.2021
https://doi.org/10.1152/ajpcell.00131.2021
Autor:
Takahiko Kiyooka, Vahagn Ohanyan, Liya Yin, Yuh Fen Pung, Yeong-Renn Chen, Chwen-Lih Chen, Patrick T. Kang, James P. Hardwick, June Yun, Danielle Janota, Joanna Peng, Christopher Kolz, Giacinta Guarini, Glenn Wilson, Inna Shokolenko, Donte A. Stevens, William M. Chilian
Publikováno v:
Basic Res Cardiol
OBJECTIVE. Endothelial dysfunction in diabetes is generally attributed to oxidative stress, but this view is challenged by observations showing antioxidants do not eliminate diabetic vasculopathy. As an alternative to oxidative stress-induced dysfunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e074cc6c117763ccd4e53bbdda1c1299
https://doi.org/10.1007/s00395-021-00908-1
https://doi.org/10.1007/s00395-021-00908-1
Autor:
James Gadd, Chris Kolz, Cody Juguilon, Yang Wang, William M. Chilian, Anurag Jamaiyar, Liya Yin, Chwen-Lih Chen, Molly Enrick, Yeong-Renn Chen, Vahagn Ohanyan, Zhiyuan Wang
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b59ac13ee1a82b809eb3e71c12ddbecc
https://doi.org/10.1096/fasebj.2021.35.s1.03588
https://doi.org/10.1096/fasebj.2021.35.s1.03588
Autor:
Liwen Zhang, Jay L. Zweier, Kunhong Xiao, William M. Chilian, Chwen-Lih Chen, Patrick T. Kang, Yeong-Renn Chen
Publikováno v:
J Mol Cell Cardiol
A serious consequence of myocardial ischemia-reperfusion injury (I/R) is oxidative damage, which causes mitochondrial dysfunction. The cascading ROS can propagate and potentially induce heme bleaching and protein cysteine sulfonation (PrSO(3)H) of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b1fee8cc963e9984da0ddbcc22d1a7
https://pubmed.ncbi.nlm.nih.gov/34331972
https://pubmed.ncbi.nlm.nih.gov/34331972
Publikováno v:
Journal of Molecular and Cellular Cardiology. 121:190-204
A serious consequence of ischemia-reperfusion injury (I/R) is oxidative damage leading to mitochondrial dysfunction. Such I/R-induced mitochondrial dysfunction is observed as impaired state 3 respiration and overproduction of O2−. The cascading ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819c02959d6f312a34a1a4097a9b8a32
https://doi.org/10.1016/j.yjmcc.2018.07.244
https://doi.org/10.1016/j.yjmcc.2018.07.244
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dab45129065076c2826c91282af78a4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.543.5
https://doi.org/10.1096/fasebj.2019.33.1_supplement.543.5
Autor:
Chwen-Lih Chen, Yeong-Renn Chen
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ea46822b4ca49926fd921706a02e5e7
https://doi.org/10.1096/fasebj.2020.34.s1.06939
https://doi.org/10.1096/fasebj.2020.34.s1.06939
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5badec7f82eb95f4118a7fe98e1f17e0
https://doi.org/10.1096/fasebj.2018.32.1_supplement.900.3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.900.3
Autor:
Yeong-Renn Chen, Patrick T. Kang, Daniel J. Luther, J. Gary Meszaros, Vahagn Ohanyan, William M. Chilian, Chwen-Lih Chen
Publikováno v:
Journal of Molecular and Cellular Cardiology. 88:14-28
During heightened cardiac work, O2 consumption by the heart benefits energy production via mitochondria. However, some electrons leak from the respiratory chain and yield superoxide, which is rapidly metabolized into H2O2 by SOD2. To understand the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469ea1b91ceec36965ff00eebd136cb7
https://doi.org/10.1016/j.yjmcc.2015.09.001
https://doi.org/10.1016/j.yjmcc.2015.09.001