Zobrazeno 1 - 10
of 760
pro vyhledávání: '"Chwee-Teck Lim"'
Autor:
Sayan Chakraborty, Divyaleka Sampath, Melissa Ong Yu Lin, Matthew Bilton, Cheng-Kuang Huang, Mui Hoon Nai, Kizito Njah, Pierre-Alexis Goy, Cheng-Chun Wang, Ernesto Guccione, Chwee-Teck Lim, Wanjin Hong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Replenishing key extracellular matrix (ECM) proteins facilitate wound healing through unclear mechanisms. Here the authors report that injury-triggered Agrin, an ECM proteoglycan, tunes a mechanocompetent niche by engaging MMP-12, thereby enforcing e
Externí odkaz:
https://doaj.org/article/66e7f31bc2564edc8b704e9a42602d0d
Autor:
Qianqian Ma, Wahyu Surya, Danxia He, Hanmeng Yang, Xiao Han, Mui Hoon Nai, Chwee Teck Lim, Jaume Torres, Yansong Miao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Actin nucleotide-dependent actin remodeling is essential to orchestrate signal transduction and cell adaptation. Rapid energy starvation requires accurate and timely reorganization of the actin network. Despite distinct treadmilling mechanis
Externí odkaz:
https://doaj.org/article/4b7436bbc5cc4d2081a6282a7ff205b2
Autor:
Jonathan Lian K Ong, Nur Fatimah Farzanah Jalaludin, Meng Kang Wong, Sheng Hui Tan, Clara Angelina, Sarvesh A. Sukhatme, Trifanny Yeo, Chwee Teck Lim, York Tien Lee, Shui Yen Soh, Tony K.H. Lim, Timothy Kwang Yong Tay, Kenneth Tou En Chang, Zhi Xiong Chen, Amos HP Loh
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102008- (2024)
Osteosarcoma is the commonest malignant bone tumor of children and adolescents and is characterized by a high risk of recurrence despite multimodal therapy, especially in metastatic disease. This suggests the presence of clinically undetected cancer
Externí odkaz:
https://doaj.org/article/54b2622737fc48fb9fbca253f177061f
Publikováno v:
Communications Materials, Vol 5, Iss 1, Pp 1-15 (2024)
Abstract Interstitial fluid (ISF), a biological fluid rich in diverse biomarkers and analytes and similar to blood composition, has garnered significant attention as a valuable source of clinically relevant information. Consequently, ISF-based wearab
Externí odkaz:
https://doaj.org/article/0f63cb304aab4a14915af715ffef2457
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing performance. In this study, we introduce a novel droplet microfluidic chip to overcome this challeng
Externí odkaz:
https://doaj.org/article/06fc2d79c7cc46e4beeecc798ac3fbdf
Autor:
Nathan Ronceray, Massimo Spina, Vanessa Hui Yin Chou, Chwee Teck Lim, Andre K. Geim, Slaven Garaj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Biological nanostructures change their shape and function in response to external stimuli, and significant efforts have been made to design artificial biomimicking devices operating on similar principles. In this work we demonstrate a progra
Externí odkaz:
https://doaj.org/article/b5529c2720b64ac7bee06e58cd23f6b0
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 021506-021506-22 (2024)
During cancer metastasis, cancer cells will encounter various microenvironments with diverse physical characteristics. Changes in these physical characteristics such as tension, stiffness, viscosity, compression, and fluid shear can generate biomecha
Externí odkaz:
https://doaj.org/article/22d27795374c45c2b9d8226cf7a983fd
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract While the human gut microbiota has a significant impact on gut health and disease, understanding of the roles of gut microbes, interactions, and collective impact of gut microbes on various aspects of human gut health is limited by the lack
Externí odkaz:
https://doaj.org/article/f8292ca0c592490caf5923e240de7119
Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue e
Autor:
Yufeng Shou, Ling Liu, Qimin Liu, Zhicheng Le, Khang Leng Lee, Hua Li, Xianlei Li, Dion Zhanyun Koh, Yuwen Wang, Tong Ming Liu, Zheng Yang, Chwee Teck Lim, Christine Cheung, Andy Tay
Publikováno v:
Bioactive Materials, Vol 24, Iss , Pp 387-400 (2023)
Bone marrow-derived mesenchymal stem cell (MSC) is one of the most actively studied cell types due to its regenerative potential and immunomodulatory properties. Conventional cell expansion methods using 2D tissue culture plates and 2.5D microcarrier
Externí odkaz:
https://doaj.org/article/abda9416b4b94ed5adc1e4e064d84bc1