Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Chwee Tat Koe"'
Autor:
Qiannan Deng, Cheng Wang, Chwee Tat Koe, Jan Peter Heinen, Ye Sing Tan, Song Li, Cayetano Gonzalez, Wing-Kin Sung, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 20, Iss 10 (2022)
Neural stem cells (NSCs) divide asymmetrically to balance their self-renewal and differentiation, an imbalance in which can lead to NSC overgrowth and tumor formation. The functions of Parafibromin, a conserved tumor suppressor, in the nervous system
Externí odkaz:
https://doaj.org/article/bf49b0e4c14d4019b05b0a6fbf4db8d0
Autor:
Song Li, Chwee Tat Koe, Su Ting Tay, Angie Lay Keng Tan, Shenli Zhang, Yingjie Zhang, Patrick Tan, Wing-Kin Sung, Hongyan Wang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The spindle matrix proteins, including Chro, are known to regulate mitotic spindle assembly in the cytoplasm. Here the authors show that in Drosophila larval brain, Chro promotes neural stem cell (NSC) reactivation and prevents activated NSCs from en
Externí odkaz:
https://doaj.org/article/56bb01d0b76b4e4b9c7eb4cb6ffab76a
Autor:
Phuong Thao Ly, Ye Sing Tan, Chwee Tat Koe, Yingjie Zhang, Gengqiang Xie, Sharyn Endow, Wu-Min Deng, Fengwei Yu, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000276 (2019)
The ability of neural stem cells (NSCs) to transit between quiescence and proliferation is crucial for brain development and homeostasis. Drosophila Hippo pathway maintains NSC quiescence, but its regulation during brain development remains unknown.
Externí odkaz:
https://doaj.org/article/e95abb8a797e4b4599072337cfefff5b
Autor:
Chwee Tat Koe, Ye Sing Tan, Max Lönnfors, Seong Kwon Hur, Christine Siok Lan Low, Yingjie Zhang, Pakorn Kanchanawong, Vytas A Bankaitis, Hongyan Wang
Publikováno v:
eLife, Vol 7 (2018)
A central feature of most stem cells is the ability to self-renew and undergo differentiation via asymmetric division. However, during asymmetric division the role of phosphatidylinositol (PI) lipids and their regulators is not well established. Here
Externí odkaz:
https://doaj.org/article/f89c1270291546408dfdbcb38f7cbefd
Autor:
Song Li, Chwee Tat Koe, Su Ting Tay, Angie Lay Keng Tan, Shenli Zhang, Yingjie Zhang, Patrick Tan, Wing-Kin Sung, Hongyan Wang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Abstract A correction to this article has been published and is linked from the HTML version of this article.
Externí odkaz:
https://doaj.org/article/cb37b6823f7e47cf9d8e2492501a8885
Autor:
Chwee Tat Koe, Song Li, Fabrizio Rossi, Jack Jing Lin Wong, Yan Wang, Zhizhuo Zhang, Keng Chen, Sherry Shiying Aw, Helena E Richardson, Paul Robson, Wing-Kin Sung, Fengwei Yu, Cayetano Gonzalez, Hongyan Wang
Publikováno v:
eLife, Vol 3 (2014)
The control of self-renewal and differentiation of neural stem and progenitor cells is a crucial issue in stem cell and cancer biology. Drosophila type II neuroblast lineages are prone to developing impaired neuroblast homeostasis if the limited self
Externí odkaz:
https://doaj.org/article/0793e30af78c4f4c8651717beb850fa3
Autor:
Yingjie Zhang, Wu-Min Deng, Fengwei Yu, Gengqiang Xie, Sharyn A. Endow, Ye Sing Tan, Chwee Tat Koe, Phuong Thao Ly, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000276 (2019)
PLoS Biology
PLoS Biology
The ability of neural stem cells (NSCs) to transit between quiescence and proliferation is crucial for brain development and homeostasis. Drosophila Hippo pathway maintains NSC quiescence, but its regulation during brain development remains unknown.
Autor:
Chwee Tat Koe, Wenhui Zong, Quan Tang, Xiaolin Tian, Sharyn A. Endow, Chunlai Wu, Wanjin Hong, Fengwei Yu, Hongyan Wang, Fabrizio Rossi, Keng Chen, Cheng Wang, Cayetano Gonzalez, Zhanyuan Benny Xing, Reshma Taneja
Publikováno v:
The Journal of Cell Biology
Drosophila Arl2 governs neuroblast asymmetric cell division through regulation of microtubule growth and localization of Msps to centrosomes.
Asymmetric division of neural stem cells is a fundamental strategy to balance their self-renewal and di
Asymmetric division of neural stem cells is a fundamental strategy to balance their self-renewal and di
Autor:
Ka Man Yu, Yun-Shen Chan, Huck-Hui Ng, John Soon Yew Lim, Lai Ping Yaw, Chaiyaboot Ariyachet, Deniz Demircioğlu, Chwee Tat Koe, Yee Siang Lim, Einsi Lynn Soe, Hongqing Liang, Kevin Andrew Uy Gonzales, Nur Halisah Binte Jumat, Yock Young Dan, Iwona Szczerbinska, Shu Hui Koh, Zhiping Lu, Cheng Peow Tan, Asim Shabbir, Graham D. Wright, Wei-Quan Tng, Muhammad Nadzim Bin Ramli
Publikováno v:
Gastroenterology. 159:1471-1486.e12
Background & Aims There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver