An endoplasmic reticulum targeting green fluorescent protein chromophore-based probe for the detection of viscosity

Autor: Xiaoqin Wei, Yiming Zhu, Xiang Yu, Lei Cai, Nanan Ruan, Luling Wu, Nengqin Jia, Tony D. James, Chusen Huang

Publikováno v: Chemical Communications. 58:10727-10730

The occurrence of endoplasmic reticulum (ER) stress is the main cause of a variety of biological processes that are closely related to numerous diseases. The homeostasis of the ER microenvironment can be disrupted under ER stress. In this research, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324d1870bde64e23025b5c71d4f1bc8d
https://doi.org/10.1039/d2cc00118g

Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications

Autor: Luling Wu, Jihong Liu, Xue Tian, Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, Hai-Hao Han, Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang, Chusen Huang, Yi Zang, Jia Li, Xiao-Peng He, Ping Li, Bo Tang, Tony D. James, Jonathan L. Sessler

Publikováno v: Journal of the American Chemical Society

Changes in adenosine triphosphate (ATP) and peroxynitrite (ONOO–) concentrations have been correlated in a number of diseases including ischemia-reperfusion injury and drug-induced liver injury. Herein, we report the development of a fluorescent pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58ac5990b76837a6ded0d79b1066c19
https://doi.org/10.1021/jacs.1c07954

Green Fluorescent Protein GFP-Chromophore-Based Probe for the Detection of Mitochondrial Viscosity in Living Cells

Autor: Xiaoqin Wei, Xiang Yu, Luling Wu, Lei Cai, Chusen Huang, Huan Li, Tony D. James

Publikováno v: Cai, L, Li, H, Yu, X, Wu, L, Wei, X, James, T D & Huang, C 2021, ' Green Fluorescent Protein GFP-Chromophore-Based Probe for the Detection of Mitochondrial Viscosity in Living Cells ', ACS Applied Bio Materials, vol. 4, no. 3, pp. 2128-2134 . https://doi.org/10.1021/acsabm.0c01446

Viscosity is a pivotal factor for indicating the dysfunction of the mitochondria. To date, most of the fluorescent probes developed for mitochondrial viscosity have been designed using BODIPY, hemicyanine, or pyridine-based molecular rotors as part o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa195c14f22bbcdee4e51e1ad1212303
https://doi.org/10.1021/acsabm.0c01446

Host‐Guest Complexation Affects Perylene‐Based Dye Aggregation

Autor: Shreya Karmacharya, Mohamed Nilam, Chusen Huang, Werner M. Nau, Khaleel I. Assaf, Gyan H. Aryal, Liming Huang

Publikováno v: ChemistrySelect. 5:5850-5854

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28f419d351c438caa680af892caad375
https://doi.org/10.1002/slct.202000702

A new long-wavelength fluorescent probe for tracking peroxynitrite in live cells and inflammatory sites of zebrafish

Autor: Chusen Huang, Chengcheng Wang, Guanyang Wang, Yang Wang, Nengqin Jia

Publikováno v: The Analyst. 145:828-835

Peroxynitrite (OONO-), as a reactive oxygen species (ROS), would be mostly profoundly implicated in diseases such as inflammation in organisms. However, bioimaging of ONOO- still faces difficulties owing to the shortage of bioimaging and real-time dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ff3c5308d6b2b851d91893cb9f15b9
https://doi.org/10.1039/c9an01934k