Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Church DN"'
Autor:
Domingo, E, Camps, C, Kaisaki, PJ, Parsons, MJ, Mouradov, D, Pentony, MM, Makino, S, Palmieri, M, Ward, RL, Hawkins, NJ, Gibbs, P, Askautrud, H, Oukrif, D, Wang, H, Wood, J, Tomlinson, E, Bark, Y, Kaur, K, Johnstone, EC, Palles, CL, Church, DN, Novelli, M, Danielsen, HE, Sherlock, J, Kerr, DJ, Kerr, R, Sieber, O, Taylor, JC, Tomlinson, I
Background Several relatively large studies have assessed molecular indicators of colorectal cancer (CRC) prognosis, but most analyses have been restricted to a handful of markers. Methods In stage II/III CRCs from the QUASAR2 clinical trial and from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d4ba01f73f5fe9e33d511c1db6cb662b
https://doi.org/10.1016/s2468-1253(18)30117-1
https://doi.org/10.1016/s2468-1253(18)30117-1
Autor:
Church, DN, Briggs, SE, Palles, C, Domingo, E, Kearsey, SJ, Grimes, JM, Gorman, M, Martin, L, Howarth, KM, Hodgson, SV, NSECG Collaborators, Kaur, K, Taylor, J, Tomlinson, IP
Accurate duplication of DNA prior to cell division is essential to suppress mutagenesis and tumour development. The high fidelity of eukaryotic DNA replication is due to a combination of accurate incorporation of nucleotides into the nascent DNA stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::56548e31fec89fd7bfbc308c25eafc7a
https://openaccess.sgul.ac.uk/id/eprint/101814/1/supp_ddt131_ddt131supp.pdf
https://openaccess.sgul.ac.uk/id/eprint/101814/1/supp_ddt131_ddt131supp.pdf
Publikováno v:
Clinical Medicine: Therapeutics; 2009, Issue 1, p557-570, 14p
Publikováno v:
Cancer Treatment Reviews; Dec2006, Vol. 32 Issue 8, p588-593, 6p
Autor:
Nowak M; Department of Pathology and Molecular Pathology, Zurich, Zurich, Switzerland., Jabbar F; Cancer Genomics and Immunology Group, The Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Rodewald AK; Department of Pathology and Molecular Pathology, Zurich, Zurich, Switzerland., Gneo L; Cancer Genomics and Immunology Group, The Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Tomasevic T; Cancer Genomics and Immunology Group, The Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Harkin A; CRUK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Iveson T; University of Southampton, Southampton, UK., Saunders M; The Christie NHS Foundation Trust, Manchester, UK., Kerr R; Department of Oncology, University of Oxford, Oxford, UK., Oein K; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Maka N; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Hay J; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Tomlinson I; Department of Oncology, University of Oxford, Oxford, UK., Sansom O; CRUK Beatson Institute of Cancer Research, Garscube Estate, Glasgow, UK., Kelly C; CRUK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Pezzella F; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Kerr D; Nuffield Department of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK., Easton A; Department of Oncology, University of Oxford, Oxford, UK., Domingo E; Department of Oncology, University of Oxford, Oxford, UK., Koelzer VH; Department of Pathology and Molecular Pathology, Zurich, Zurich, Switzerland; Department of Oncology, University of Oxford, Oxford, UK; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland., Church DN; Cancer Genomics and Immunology Group, The Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: dchurch@well.ox.ac.uk.
Publikováno v:
Cell reports. Medicine [Cell Rep Med] 2024 Sep 17; Vol. 5 (9), pp. 101727.
Autor:
Cornish AJ; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Gruber AJ; Department of Biology, University of Konstanz, Konstanz, Germany.; Manchester Cancer Research Centre, Division of Cancer Sciences, University of Manchester, Manchester, UK., Kinnersley B; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.; University College London Cancer Institute, London, UK., Chubb D; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Frangou A; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany., Caravagna G; Department of Mathematics and Geosciences, University of Trieste, Trieste, Italy.; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK., Noyvert B; Cancer Research UK Centre and Centre for Computational Biology, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Lakatos E; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK.; Department of Mathematical Sciences, Chalmers University of Technology, Gothenburg, Sweden., Wood HM; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Thorn S; Department of Oncology, University of Oxford, Oxford, UK., Culliford R; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Arnedo-Pac C; Institute for Research in Biomedicine Barcelona, The Barcelona Institute of Science and Technology, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Househam J; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK., Cross W; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK.; Research Department of Pathology, University College London, UCL Cancer Institute, London, UK., Sud A; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Law P; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK., Leathlobhair MN; Trinity College, Dublin, Ireland., Hawari A; Manchester Cancer Research Centre, Division of Cancer Sciences, University of Manchester, Manchester, UK., Woolley C; Department of Oncology, University of Oxford, Oxford, UK., Sherwood K; Department of Oncology, University of Oxford, Oxford, UK.; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Feeley N; Department of Oncology, University of Oxford, Oxford, UK.; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Gül G; Edinburgh Cancer Research, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Fernandez-Tajes J; Department of Oncology, University of Oxford, Oxford, UK., Zapata L; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK., Alexandrov LB; Department of Cellular and Molecular Medicine, UC San Diego, La Jolla, CA, USA.; Department of Bioengineering, UC San Diego, La Jolla, CA, USA.; Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Murugaesu N; Genomics England, William Harvey Research Institute, Queen Mary University of London, London, UK., Sosinsky A; Genomics England, William Harvey Research Institute, Queen Mary University of London, London, UK., Mitchell J; Genomics England, William Harvey Research Institute, Queen Mary University of London, London, UK., Lopez-Bigas N; Institute for Research in Biomedicine Barcelona, The Barcelona Institute of Science and Technology, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Quirke P; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK., Church DN; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Tomlinson IPM; Department of Oncology, University of Oxford, Oxford, UK. ian.tomlinson@oncology.ox.ac.uk., Sottoriva A; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK.; Computational Biology Research Centre, Human Technopole, Milan, Italy., Graham TA; Centre for Evolution and Cancer, Institute of Cancer Research, London, UK., Wedge DC; Manchester Cancer Research Centre, Division of Cancer Sciences, University of Manchester, Manchester, UK., Houlston RS; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Publikováno v:
Nature [Nature] 2024 Sep; Vol. 633 (8028), pp. 127-136. Date of Electronic Publication: 2024 Aug 07.
Autor:
Taieb J; Institut du Cancer Paris CARPEM, Gastroenterology and Digestive Oncology Department, APHP.Centre - Université Paris Cité, Hôpital Européen G. Pompidou, France; Centre de Recherche des Cordeliers, Sorbonne Université, INSERM, Université Paris Cité, France. Electronic address: jtaieb75@gmail.com., Basile D; Division of Medical Oncology, San Giovanni di Dio Hospital, Crotone, Italy., Seligmann J; St James's University Hospital, Leeds, United Kingdom., Argiles G; Memorial Sloan Kettering Cancer Center, New York, NY, USA., André T; Sorbonne Université and department of Medical Oncology, Hospital Saint Antoine and INSERM 938 and SIRIC CURAMUS, Paris, France., Gallois C; Institut du Cancer Paris CARPEM, Gastroenterology and Digestive Oncology Department, APHP.Centre - Université Paris Cité, Hôpital Européen G. Pompidou, France; Centre de Recherche des Cordeliers, Sorbonne Université, INSERM, Université Paris Cité, France., Goldberg RM; West Virginia University Cancer Institute and the Mary Babb Randolph Cancer Center, Morgantown, WV., Yothers G; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA., Sobrero A; Department of Medical Oncology, IRCCS San Martino, Genoa, Italy., Meyerhardt JA; Dana-Farber Cancer Institute, Boston, MA., Souglakos J; Department of Medical Oncology, University General Hospital of Heraklion, 71110 Heraklion, Greece., Labianca R; Ospdale Papa Giovanni XXIII, Bergamo, Italy., Iveson T; University Hospital Southampton NHS Trust, Southampton, United Kingdom., Church DN; Oxford Cancer Centre, University of Oxford, Oxford, UK., Arnold D; Asklepios Tumorzentrum Hamburg, Department of Oncology and Hematology, AK Altona, Hamburg, Germany., Tie J; Department of Medical Oncology, Peter MacCallum Cancer Centre, Parkville, VIC, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia; Division of Personalised Oncology, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., Gill S; BC Cancer, Vancouver, Canada., Laurent-Puig P; Centre de Recherche des Cordeliers, Sorbonne Université, INSERM, Université de Paris, EPIGENETEC, 75006 Paris, France., Yoshino T; National Cancer Center Hospital East, Chiba, Japan., Lonardi S; Istituto Oncologico Veneto IOV-IRCCS, Padova, Italy., Shi Q; Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN, USA.
Publikováno v:
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2024 Jul; Vol. 206, pp. 114118. Date of Electronic Publication: 2024 May 15.
Autor:
Domingo E; Department of Oncology, University of Oxford, Oxford, United Kingdom.; CRUK Beatson Institute of Cancer Research, Garscube Estate, Glasgow, United Kingdom., Kelly C; CRUK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, United Kingdom., Hay J; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Sansom O; CRUK Beatson Institute of Cancer Research, Garscube Estate, Glasgow, United Kingdom., Maka N; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Oien K; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Iveson T; University of Southampton, Southampton, United Kingdom., Saunders M; The Christie NHS Foundation Trust, Manchester, United Kingdom., Kerr R; Department of Oncology, University of Oxford, Oxford, United Kingdom., Tomlinson I; Department of Oncology, University of Oxford, Oxford, United Kingdom., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Harkin A; CRUK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, United Kingdom., Nowak M; Department of Pathology and Molecular Pathology, Zurich, Switzerland., Koelzer V; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Pathology and Molecular Pathology, Zurich, Switzerland., Easton A; Department of Oncology, University of Oxford, Oxford, United Kingdom., Boukovinas I; Medical Oncology Unit Department, Bioclinic Oncology Unit of Thessaloniki, Thessaloniki, Greece., Moustou E; Pathology, University Hospital of Heraklion, Crete, Greece., Messaritakis I; Laboratory of Translational Oncology, University of Crete-School of Medicine, Heraklion, Greece., Chondrozoumaki M; Laboratory of Tumor Cell Biology, University of Crete - School of Medicine, Heraklion, Greece., Karagianni M; Laboratory of Translational Oncology, University of Crete-School of Medicine, Heraklion, Greece., Pagès F; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Université de Paris Cité, Cordeliers Research Center, Paris, France.; Assistance Publique-Hôpitaux de Paris (AP-HP), Immunomonitoring Platform, Georges Pompidou European Hospital, Paris, France., Arnoux F; VERACYTE, Marseille, France., Lautard C; VERACYTE, Marseille, France., Lovera Y; VERACYTE, Marseille, France., Boquet I; VERACYTE, Marseille, France., Catteau A; VERACYTE, Marseille, France., Galon J; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Université de Paris Cité, Cordeliers Research Center, Paris, France.; VERACYTE, Marseille, France., Souglakos I; Laboratory of Translational Oncology, University of Crete-School of Medicine, Heraklion, Greece.; Department of Medical Oncology, University General Hospital of Heraklion, Heraklion, Greece., Church DN; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Jun 20; Vol. 42 (18), pp. 2207-2218. Date of Electronic Publication: 2024 Mar 14.
Autor:
Frei AL; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Life Science Zurich Graduate School, PhD Program in Biomedicine, University of Zurich, Zurich, Switzerland., McGuigan A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sinha RRAK; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jabbar F; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gneo L; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tomasevic T; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Harkin A; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Iveson T; Southampton University, Southampton, UK., Saunders MP; The Christie NHS Foundation Trust, Manchester, UK., Oien KA; School of Cancer Sciences, University of Glasgow, Glasgow, UK; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Maka N; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Pezzella F; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK., Campo L; Department of Oncology, University of Oxford, Oxford, UK., Browne M; Department of Oncology, University of Oxford, Oxford, UK., Glaire M; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kildal W; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway., Danielsen HE; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway., Hay J; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sansom O; School of Cancer Sciences, University of Glasgow, Glasgow, UK; Cancer Research UK Beatson Institute of Cancer Research, Glasgow, UK; Cancer Research UK Scotland Centre, Glasgow and Edinburgh, UK., Kelly C; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Tomlinson I; Department of Oncology, University of Oxford, Oxford, UK., Kerr R; Department of Oncology, University of Oxford, Oxford, UK., Kerr D; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK., Domingo E; Department of Oncology, University of Oxford, Oxford, UK; Cancer Research UK Scotland Centre, Glasgow and Edinburgh, UK., Church DN; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: david.church@well.ox.ac.uk., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Department of Oncology, University of Oxford, Oxford, UK.
Publikováno v:
The Lancet. Oncology [Lancet Oncol] 2024 Feb; Vol. 25 (2), pp. 198-211.
Autor:
Frei AL; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Life Science Zurich Graduate School, PhD Program in Biomedicine, University of Zurich, Zurich, Switzerland., McGuigan A; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sinha RR; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Glaire MA; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jabbar F; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gneo L; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tomasevic T; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Harkin A; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Iveson TJ; Southampton University Hospital NHS Foundation Trust, Southampton, UK., Saunders M; The Christie NHS Foundation Trust, Manchester, UK., Oein K; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Maka N; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Pezella F; Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, UK., Campo L; Department of Oncology, University of Oxford, Oxford, UK., Hay J; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sansom OJ; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Cancer Research UK Beatson Institute, Glasgow, UK.; Cancer Research UK Scotland Centre, Edinburgh and Glasgow, UK., Kelly C; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Tomlinson I; Department of Oncology, University of Oxford, Oxford, UK., Kildal W; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway., Kerr RS; Department of Oncology, University of Oxford, Oxford, UK., Kerr DJ; Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, UK., Danielsen HE; Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, UK.; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway.; Department of Informatics, University of Oslo, Oslo, Norway., Domingo E; Department of Oncology, University of Oxford, Oxford, UK.; Cancer Research UK Scotland Centre, Edinburgh and Glasgow, UK., Church DN; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK.
Publikováno v:
The journal of pathology. Clinical research [J Pathol Clin Res] 2023 Nov; Vol. 9 (6), pp. 449-463. Date of Electronic Publication: 2023 Sep 11.