Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Chunyu, Gu"'
Autor:
Weihai Ning, Xiao Qian, Louisa Chard Dunmall, Funan Liu, Yuduo Guo, Shenglun Li, Dixiang Song, Deshan Liu, Lixin Ma, Yanming Qu, Haoran Wang, Chunyu Gu, Mingshan Zhang, Yaohe Wang, Shengdian Wang, Hongwei Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Malignant glioma is a highly fatal central nervous system malignancy with high recurrence rates. Oncolytic viruses offer potential treatment but need improvement in efficacy and safety. Here we describe a phase I, dose-escalating, single arm
Externí odkaz:
https://doaj.org/article/dc2220237c314540a478ed57334e9ea9
Autor:
Jiao Kong, Hongqian Kui, Yue Tian, Xianbin Kong, Tao He, Qingbo Li, Chunyu Gu, Jinhe Guo, Chuanxin Liu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 264, Iss , Pp 115392- (2023)
Adverse reactions to traditional Chinese medicine have hindered the healthy development and internationalization process of the traditional Chinese medicine industry. The critical issue that needs to be solved urgently is to evaluate the safety of tr
Externí odkaz:
https://doaj.org/article/b94f68d9143945e389528467952b4fbb
Publikováno v:
Italian Journal of Pediatrics, Vol 48, Iss 1, Pp 1-6 (2022)
Abstract Background Prader-Willi syndrome (PWS) is a multisystemic complex genetic disorder caused by the loss of paternally expressed genes in the human chromosome region 15q11.2-q13. It is characterized by severe hypotonia and feeding difficulties
Externí odkaz:
https://doaj.org/article/7f17e2b2f7f84ee09a5658d71e8a9b8d
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-5 (2022)
Abstract Background Variants in the DEPDC5 have been proved to be main cause of not only various dominant familial focal epilepsies, but also sporadic focal epilepsies. In the present study, a novel variant in DEPDC5 was detected in the patient with
Externí odkaz:
https://doaj.org/article/e6660956ec24496f986017119887fa9e
Autor:
Yan Liu, Liang Dong, Xiufang Zhi, Yang Liu, Linsheng Zhao, Xiaowei Xu, Lu Wang, Jie Zheng, Linjie Pu, Chunyu Gu, Jianbo Shu, Chunquan Cai
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Background To screen the single nucleotide polymorphisms (SNPs) in the coding regions of VANGL and FZD family members related to the plane cell polarity (PCP) signaling pathway in neural tube defects (NTDs) patients, so as to provide theoret
Externí odkaz:
https://doaj.org/article/43fdc44bfdfd48658c413f6a54420ef6
Publikováno v:
Chemical Physics Impact, Vol 5, Iss , Pp 100118- (2022)
Manganese-cerium catalyst has attracted much attention due to its extraordinarily good low-temperature performance for detrinification technology, but its poor SO2 resistance limits its wide application. A suitable catalyst carrier can enhance the lo
Externí odkaz:
https://doaj.org/article/85f1eef2bb2f464eaa0bc810d088c383
Autor:
Xiaofang Chen, Jia Fu, Ying Qian, Xiufang Zhi, Linjie Pu, Chunyu Gu, Jianbo Shu, Ling Lv, Chunquan Cai
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Low vitamin D levels may play a role in type 1 diabetes (T1D) susceptibility. Since 25(OH)D synthesis is genetically regulated, single nucleotide polymorphisms (SNPs) of important genes have also been shown to modulate the risk of T1D, so this study
Externí odkaz:
https://doaj.org/article/9e9070d633f44b1283f66b066777f41d
Case report: Altered pre-mRNA splicing caused by intronic variant c.1499 + 1G > A in the SLC4A4 gene
Autor:
Yan Liu, Wenchao Sheng, Jinying Wu, Jie Zheng, Xiufang Zhi, Shuyue Zhang, Chunyu Gu, Detong Guo, Wenhong Wang
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Proximal renal tubular acidosis (pRTA) with ocular abnormalities is an autosomal recessive disease caused by variants in the Solute Carrier Family 4 Member 4 (SLC4A4) gene. Patients present with metabolic acidosis and low plasma bicarbonate concentra
Externí odkaz:
https://doaj.org/article/a15311fe243f47fb982a2502f159cad4
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundMethylmalonic acid (MMA) is an intermediate metabolite of human body. The content of MMA in the blood of healthy people is very low, and its concentration will increase in some diseases and elderly people. Recent studies have shown that MMA
Externí odkaz:
https://doaj.org/article/10b7af7afeb9474b81fd94f771229dba
Publikováno v:
Italian Journal of Pediatrics, Vol 46, Iss 1, Pp 1-6 (2020)
Abstract Background Spinal muscular atrophy (SMA) is an autosomal recessive hereditary disease associated with severe muscle atrophy and weakness in the limbs and trunk. The discovery of mutated genes is helpful in diagnosis and treatment for SMA. Me
Externí odkaz:
https://doaj.org/article/43135657b4674b8f86285a2633e747b9