Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chunyi Shen"'
Autor:
Jiqi Shan, Wei Jing, Yu Ping, Chunyi Shen, Dong Han, Fengsen Liu, Yaqing Liu, Congcong Li, Yi Zhang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTAnti-PD-1 antibody therapy has achieved success in tumor treatment; however, the duration of its clinical benefits are typically short. The functional state of intratumoral CD8+ T cells substantially affects the efficacy of anti-PD-1 antibody
Externí odkaz:
https://doaj.org/article/40929eb3d9084be095904ba4d74e9276
Autor:
Chunyi Shen, Zhen Zhang, Yonggui Tian, Feng Li, Lingxiao Zhou, Wenyi Jiang, Li Yang, Bin Zhang, Liping Wang, Yi Zhang
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Chimeric antigen receptor T (CAR-T) cell therapy has limited effects in the treatment of solid tumors. Sulforaphane (SFN) is known to play an important role in inhibiting tumor growth, but its effect on CAR-T cells remains unclear
Externí odkaz:
https://doaj.org/article/fa4414bc3272439a9714929ad02b2689
LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-11 (2021)
Abstract The refractory of castration-resistant prostate cancer (CRPC) is mainly reflected in drug resistance. The current research on the resistance mechanism of CRPC is still in its infancy. In this study, we revealed for the first time the key rol
Externí odkaz:
https://doaj.org/article/d804c2af02a6416e83b567fbe4f55b29
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Colorectal cancer (CRC) is the third most common cancer in the world. Although there are standard treatment options for CRC, most patients respond poorly to these treatments. Immunotherapies have gradually emerged due to the increasing awareness and
Externí odkaz:
https://doaj.org/article/8ed788fedc704afca2ba60bdf2d369b1
Publikováno v:
Cells, Vol 11, Iss 19, p 3103 (2022)
T cells play central roles in the anti-tumor immunity, whose activation and differentiation are profoundly regulated by intrinsic metabolic reprogramming. Emerging evidence has revealed that metabolic processes of T cells are generally altered by tum
Externí odkaz:
https://doaj.org/article/0c760ac2062a4294aa0f41431175a9b8
Autor:
Chunyi Shen, Chaojun Liu, Zhen Zhang, Yu Ping, Jingwen Shao, Yonggui Tian, Weina Yu, Guohui Qin, Shasha Liu, Liping Wang, Yi Zhang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThere is increasing evidence that group 2 innate lymphoid cells (ILC2s) play an essential role in allergy and parasitic infection. However, the role of ILC2s in human lung cancer remains unclear.MethodsILC2s from peripheral blood mononuclea
Externí odkaz:
https://doaj.org/article/d736f4099110474eb74b7d58943360db
Autor:
Yi Zhang, Jinyao Lian, Yamin Qiao, Lan Huang, Qitai Zhao, Shumin Wang, Chunyi Shen, Weina Yu, Shasha Liu, Dan Wang, Guohui Qin, Feifei Ren
Publikováno v:
Cancer Letters. 518:35-48
Drug resistance remains the major obstacle limiting the effectiveness of chemotherapy for esophageal squamous cell carcinoma (ESCC)[1]. However, how stromal cells cooperate with immune cells to contribute to drug resistance is not yet fully understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e8cbfac1041abed0c0635c48718aad
https://doi.org/10.1016/j.canlet.2021.06.009
https://doi.org/10.1016/j.canlet.2021.06.009
Autor:
Zhen Zhang, Liping Wang, Kai Zhang, Chaoqi Zhang, Yonggui Tian, Qun Gao, Yi Zhang, Chunyi Shen, Feng Li, Yu Ping, Nomathamsanqa Resegofetse Maimela, Ling Cao, Bin Zhang
Publikováno v:
The Journal of Immunology. 204:2575-2588
Metformin has been studied for its anticancer effects by regulating T cell functions. However, the mechanisms through which metformin stimulates the differentiation of memory T cells remain unclear. We found that the frequencies of memory stem and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200eee98572d6ef4deb6c50f98bd5255
https://doi.org/10.4049/jimmunol.1901213
https://doi.org/10.4049/jimmunol.1901213
Gamification provides a practical approach to improving learning processes, especially the learner's motivation. However, little research has been conducted on student intentions to use gamification in higher education. Therefore, this study explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1b7029c80f1238d38a043e050092f2
https://doi.org/10.4018/978-1-6684-3710-0.ch090
https://doi.org/10.4018/978-1-6684-3710-0.ch090
Autor:
Lingxiao Zhou, Wenyi Jiang, Yonggui Tian, Zhen Zhang, Chunyi Shen, Liping Wang, Feng Li, Yi Zhang, Li Yang, Bin Zhang
Publikováno v:
BMC Medicine
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Background Chimeric antigen receptor T (CAR-T) cell therapy has limited effects in the treatment of solid tumors. Sulforaphane (SFN) is known to play an important role in inhibiting tumor growth, but its effect on CAR-T cells remains unclear. The goa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196848ec461496896aab97338f40ce32
https://doi.org/10.1186/s12916-021-02161-8
https://doi.org/10.1186/s12916-021-02161-8