Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Chunyi Hu"'
Publikováno v:
mLife, Vol 3, Iss 3, Pp 384-386 (2024)
Externí odkaz:
https://doaj.org/article/3723712c227f427286c72353959a6c95
Autor:
Tao Hu, Quanquan Ji, Xinxin Ke, Hufeng Zhou, Senfeng Zhang, Shengsheng Ma, Chenlin Yu, Wenjun Ju, Meiling Lu, Yu Lin, Yangjing Ou, Yingsi Zhou, Yibei Xiao, Chunlong Xu, Chunyi Hu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract R-loop-triggered collateral single-stranded DNA (ssDNA) nuclease activity within Class 1 Type I CRISPR-Cas systems holds immense potential for nucleic acid detection. However, the hyperactive ssDNase activity of Cas3 introduces unwanted nois
Externí odkaz:
https://doaj.org/article/814c81b3af0e478eb569a55abc863455
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Heterochromatin is generally associated with the nuclear periphery, but how the spatial organization of heterochromatin is regulated to ensure epigenetic silencing remains unclear. Here we found that Sad1, an inner nuclear membrane SUN-famil
Externí odkaz:
https://doaj.org/article/b5219f716342407eb6ec6d174fcc5a6e
Autor:
Meiling Lu, Chenlin Yu, Yuwen Zhang, Wenjun Ju, Zhi Ye, Chenyang Hua, Jinze Mao, Chunyi Hu, Zhenhuang Yang, Yibei Xiao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Type I CRISPR-Cas systems employ multi-subunit effector Cascade and helicase-nuclease Cas3 to target and degrade foreign nucleic acids, representing the most abundant RNA-guided adaptive immune systems in prokaryotes. Their ability to cause
Externí odkaz:
https://doaj.org/article/84267b5219e74719a48722c57feb41b4
Publikováno v:
Engineering Microbiology, Vol 4, Iss 3, Pp 100156- (2024)
The adaptive survival mechanisms of bacterial pathogens under host-induced stress are crucial for understanding pathogenesis. Recently, Uppalapati et al. revealed a unique dual function of the Gifsy-1 prophage terminase in Salmonella enterica: it act
Externí odkaz:
https://doaj.org/article/56fddfb9a325418dbecb3a1f9e526f8c
Autor:
Zhifang Li, Ruochen Guo, Xiaozhi Sun, Guoling Li, Zhuang Shao, Xiaona Huo, Rongrong Yang, Xinyu Liu, Xi Cao, Hainan Zhang, Weihong Zhang, Xiaoyin Zhang, Shuangyu Ma, Meiling Zhang, Yuanhua Liu, Yinan Yao, Jinqi Shi, Hui Yang, Chunyi Hu, Yingsi Zhou, Chunlong Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Transposon-associated ribonucleoprotein TnpB is known to be the ancestry endonuclease of diverse Cas12 effector proteins from type-V CRISPR system. Given its small size (408 aa), it is of interest to examine whether engineered TnpB could be
Externí odkaz:
https://doaj.org/article/c79878c9e3d04341a1e387a6cdc1a366
Autor:
Alessandro Cicconi, Rekha Rai, Xuexue Xiong, Cayla Broton, Amer Al-Hiyasat, Chunyi Hu, Siying Dong, Wenqi Sun, Jennifer Garbarino, Ranjit S. Bindra, Carl Schildkraut, Yong Chen, Sandy Chang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Primary microcephaly is a clinical feature of several human telomere disorder syndromes. Here the authors reveal a role of Microcephalin 1 in promoting telomere replication and repair.
Externí odkaz:
https://doaj.org/article/1ffe736cceae4b6a9ede6a1d1309b5e3
Publikováno v:
Science. 6/24/2022, Vol. 376 Issue 6600, p1476-1481. 6p. 4 Diagrams.
Autor:
Chunyi Hu, Qiang Sun, Peng He, Lina Song, Jiankun Hu, Xiao Hou, Xiaoli Zhan, Yongyuan Ren, Quan Liu, Qinghua Zhang
Publikováno v:
ACS Applied Nano Materials. 5:18349-18356
Publikováno v:
Journal of Veterinary Science. 24