Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chunye Huang"'
Autor:
Xiaofeng Dai, Zhipeng Wu, Ruiwen Ruan, Jingyi Chen, Chunye Huang, Wan Lei, Yangyang Yao, Li Li, Xiaomei Tang, Jianping Xiong, Miao Feng, Jun Deng
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background The effectiveness of anti-programmed cell death protein 1(PD-1)/programmed cell death 1 ligand 1(PD-L1) therapy in treating certain types of cancer is associated with the level of PD-L1. However, this relationship has not been obs
Externí odkaz:
https://doaj.org/article/f2755672ca074efc8e3c8e6dd3201ac5
Autor:
Qinru Zeng, Shaocheng Zeng, Xiaofeng Dai, Yun Ding, Chunye Huang, Ruiwen Ruan, Jianping Xiong, Xiaomei Tang, Jun Deng
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101279- (2024)
Murine double minute 2 (MDM2) plays an essential role in the cell cycle, apoptosis, DNA repair, and oncogene activation through p53-dependent and p53-independent signaling pathways. Several preclinical studies have shown that MDM2 is involved in tumo
Externí odkaz:
https://doaj.org/article/5c3d035b07814623999d9ce31242e788
Autor:
Ruiwen Ruan, Li Li, Xuan Li, Chunye Huang, Zhanmin Zhang, Hongguang Zhong, Shaocheng Zeng, Qianqian Shi, Yang Xia, Qinru Zeng, Qin Wen, Jingyi Chen, Xiaofeng Dai, Jianping Xiong, Xiaojun Xiang, Wan Lei, Jun Deng
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Background Fibroblast growth factors (FGFs) and their receptors (FGFRs) play a crucial role in cell fate and angiogenesis, with dysregulation of the signaling axis driving tumorigenesis. Therefore, many studies have targeted FGF/FGFR signali
Externí odkaz:
https://doaj.org/article/2a28eefe3ad142c28643b99db41f1e94
Autor:
Yangyang Yao, Zhen Liu, Shanshan Huang, Chunye Huang, Yuan Cao, Li Li, Hui Guo, Fenfen Liu, Shipeng Huang, Quan Liao, Xin He, Jun Chen, Junhe Li, Xiaojun Xiang, Jianping Xiong, Jun Deng
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract F-box and WD repeat domain-containing 5 (FBXW5), with WD40 repeats, can bind to the PPxY sequence of the large tumor suppressor kinases 1/2 (LATS1/2) kinase domain, resulting in ubiquitination. Ubiquitination and the subsequent degradation o
Externí odkaz:
https://doaj.org/article/031fc1aa239644b5ab94fb9df2b9071e
Publikováno v:
Cancer Treatment and Research Communications, Vol 31, Iss , Pp 100568- (2022)
According to previous reports,10–16% of patients with clinically advanced cholangiocarcinoma develop FGFR2 fusions or rearrangements. Treatment with FGFR2-specific inhibitors (tyrosine kinase inhibitors, TKIs) has proven effective for patients with
Externí odkaz:
https://doaj.org/article/c28410bead754dd69dbe2ef0c3c4755d
Autor:
Zhen Liu, Junhe Li, Yun Ding, Mei Ma, Jun Chen, Wan Lei, Li Li, Yangyang Yao, Xin Yu, Min Zhong, Quan Liao, Weidan Fang, Linwei Fan, Chunye Huang, Hongguang Zhong, Qin Wen, Zi Fang, Jingyi Chen, Shanshan Huang, Jianpin Xiong, Xiaojun Xiang, Jun Deng
Publikováno v:
Oncogene. 41:2555-2570
The importance of the Hippo-Yes-associated protein 1 (YAP1) pathway in gastric carcinogenesis and metastasis has attracted considerable research attention; however, the regulatory network of YAP1 in gastric cancer (GC) is not completely understood. I
Publikováno v:
OncoTargets and Therapy. 13:10075-10085
Purpose Programmed death ligand 1 (PD-L1) is widely used for predicting immune checkpoint inhibitors but has a limited effect on predicting clinical response. The aim of this study was to examine the prognostic value and PD-1 inhibitor therapeutic ef
Publikováno v:
OncoTargets and therapy
Purpose Programmed death ligand 1 (PD-L1) is widely used for predicting immune checkpoint inhibitors but has a limited effect on predicting clinical response. The aim of this study was to examine the prognostic value and PD-1 inhibitor therapeutic ef