Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Chunyan Liao"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract Astrocytes, the predominant glial cells in the central nervous system, play essential roles in maintaining brain function. Reprogramming induced pluripotent stem cells (iPSCs) to become astrocytes through overexpression of the transcription
Externí odkaz:
https://doaj.org/article/1958f0f2d8bd44cb9c737c3da3589278
Publikováno v:
Zhongguo gonggong weisheng, Vol 39, Iss 7, Pp 908-912 (2023)
Objective To detect pathogenic microorganisms in secondary water supply for high-rise buildings in Chongqing city and to examine the spectrum, dominant strains, virulence genes and drug resistance of the isolated pathogenic bacteria. Methods A total
Externí odkaz:
https://doaj.org/article/22d12b5599664290b0621d43aacf90ae
Publikováno v:
Materials & Design, Vol 236, Iss , Pp 112461- (2023)
The high incidence of metastases remains a major hurdle for triple negative breast cancer (TNBC) treatment. Herein, we developed a fairly safe anticancer nanodrug for TNBC treatment by loading Epigallocatechin-3-gallate (EGCG) in cross-linked lipoic
Externí odkaz:
https://doaj.org/article/931230ab9199403bbb5fa459534f4ee0
Autor:
Jiacheng Zhang, Shuyan Chi, Beiping Tan, Xiaohui Dong, Shuang Zhang, Weixing Liang, Wenhao Gao, Chunyan Liao, Hongjin Deng
Publikováno v:
Aquaculture Reports, Vol 29, Iss , Pp 101485- (2023)
Hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus lanceolatu) is a popular aquaculture species in recent years. The latest research has found that cottonseed protein concentrate (CPC) has been found to be an effective alternative to fish
Externí odkaz:
https://doaj.org/article/faa52a20cea94486a79969e957237826
Autor:
Bei Zhang, Shanyong Mao, Xingde Liu, Sha Li, Haiyan Zhou, Ying Gu, Wupeng Liu, Lei Fu, Chunyan Liao, Pengzhen Wang
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-12 (2021)
Abstract Background Although miR-125b plays a crucial role in many human cancers. However, its function in heart failure (HF) remains unclear. Our study aimed to investigate its involvement in heart failure. Methods In this study, the mouse HF model
Externí odkaz:
https://doaj.org/article/e14a6ab41d9c4672b3c62f4dcee766a6
Autor:
Hannah M. Southam, Thomas W. Smith, Rhiannon L. Lyon, Chunyan Liao, Clare R. Trevitt, Laurence A. Middlemiss, Francesca L. Cox, Jonathan A. Chapman, Sherif F. El-Khamisy, Michael Hippler, Michael P. Williamson, Peter J.F. Henderson, Robert K. Poole
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 114-123 (2018)
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds, are extensively used as experimental tools to deliver CO, a biological ‘gasotransmitter’, in mammalian systems. CORMs are also explored as potential novel antimicr
Externí odkaz:
https://doaj.org/article/4150f0a8aae44753affcb365c4711a5e
Autor:
Chunyan Liao, Ryan Beveridge, Jessica J.R. Hudson, Jacob D. Parker, Shih-Chieh Chiang, Swagat Ray, Mohamed E. Ashour, Ian Sudbery, Mark J. Dickman, Sherif F. El-Khamisy
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3352-3365 (2018)
Summary: Genomic damage can feature DNA-protein crosslinks whereby their acute accumulation is utilized to treat cancer and progressive accumulation causes neurodegeneration. This is typified by tyrosyl DNA phosphodiesterase 1 (TDP1), which repairs t
Externí odkaz:
https://doaj.org/article/ba5874b13fb94344979914ea868f0b6c
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1215 (2021)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that manifests as cognitive deficits and memory decline, especially in old age. Several biomarkers have been developed to monitor AD progression. Given that the retina and brain s
Externí odkaz:
https://doaj.org/article/ca0371edff31406d9b60a966b0750db8
Autor:
Alan Diot, Thomas Agnew, Jeremy Sanderson, Chunyan Liao, Janet Carver, Ricardo Pires das Neves, Rajeev Gupta, Yanping Guo, Caroline Waters, Sharon Seto, Matthew J. Daniels, Eszter Dombi, Tiffany Lodge, Karl Morten, Suzannah A. Williams, Tariq Enver, Francisco J. Iborra, Marcela Votruba, Joanna Poulton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Background: Autosomal dominant optic atrophy (ADOA) is usually caused by mutations in the essential gene, OPA1. This encodes a ubiquitous protein involved in mitochondrial dynamics, hence tissue specificity is not understood. Dysregulated mitophagy (
Externí odkaz:
https://doaj.org/article/0360b3470f94428a8df73eee35831c9f
Autor:
Li Zhong, Zhen-Lian Zhang, Xinxiu Li, Chunyan Liao, Pengfei Mou, Tingting Wang, Zongqi Wang, Zhe Wang, Min Wei, Huaxi Xu, Guojun Bu, Xiao-Fen Chen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
DNAX-activating protein of 12 kDa (DAP12) is a signaling adapter protein expressed in cells that participate in innate immune responses. By pairing with different triggering receptors expressed on myeloid cell (TREM) proteins, DAP12 can mediate both
Externí odkaz:
https://doaj.org/article/5a9c7de68c654eacaacd510798f77858