Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chunyan Gu-Trantien"'
Autor:
Pushpamali De Silva, Soizic Garaud, Cinzia Solinas, Alexandre de Wind, Gert Van den Eyden, Vinu Jose, Chunyan Gu-Trantien, Edoardo Migliori, Anaïs Boisson, Céline Naveaux, Hugues Duvillier, Ligia Craciun, Denis Larsimont, Martine Piccart-Gebhart, Karen Willard-Gallo
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 226-238 (2019)
Background: FOXP1, a transcriptional regulator of lymphocyte development, is abnormally expressed in some human tumors. This study investigated FOXP1-mediated regulation of tumor infiltrating lymphocytes (TIL) in untreated primary breast cancer (BC).
Externí odkaz:
https://doaj.org/article/abec8ec94bac403a8e0f4ccc86990f3b
Autor:
Vu Luan Dang Chi, Soizic Garaud, Pushpamali De Silva, Vincent Thibaud, Basile Stamatopoulos, Mimoune Berehad, Chunyan Gu-Trantien, Mohammad Krayem, Hugues Duvillier, Jean-Nicolas Lodewyckx, Karen Willard-Gallo, Catherine Sibille, Dominique Bron
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Age-related genetic changes in lymphocyte subsets are not currently well documented. BACH2 is a transcription factor that plays an important role in immune-mediated homeostasis by tightly regulating PRDM1 expression in both B-cell
Externí odkaz:
https://doaj.org/article/b5f6f730ed624098b718e65231b633af
Autor:
Yasmina Serroukh, Chunyan Gu-Trantien, Baharak Hooshiar Kashani, Matthieu Defrance, Thien-Phong Vu Manh, Abdulkader Azouz, Aurélie Detavernier, Alice Hoyois, Jishnu Das, Martin Bizet, Emeline Pollet, Tressy Tabbuso, Emilie Calonne, Klaas van Gisbergen, Marc Dalod, François Fuks, Stanislas Goriely, Arnaud Marchant
Publikováno v:
eLife, Vol 7 (2018)
Cytotoxic CD4 (CD4CTX) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their development remains poorly understood. In the context of human cytomegalovirus infection, a significant propor
Externí odkaz:
https://doaj.org/article/82779754636643bd9037d7babaacbad5
Autor:
Agnieszka Pozdzik, Ingrid Beukinga, Chunyan Gu-Trantien, Karen Willard-Gallo, Joëlle Nortier, Olivier Pradier
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Membranous nephropathy (MN) is a kidney specific autoimmune disease mainly mediated by anti-phospholipase A2 receptor 1 autoantibody (PLA2R1 Ab). The adequate assessment of chimeric anti-CD20 monoclonal antibody, rituximab (RTX), efficacy is still ne
Externí odkaz:
https://doaj.org/article/2b22481ad4e044bca08900c5c82b80ff
Autor:
Cinzia Solinas, Marco Aiello, Karen Willard-Gallo, Chunyan Gu-Trantien, Edoardo Migliori, Pushpamali De Silva
Publikováno v:
International Journal of Cancer. 149:31-41
Immunotherapy approaches boosting spontaneous and durable antitumor immune responses through immune checkpoint blockade are revolutionizing treatment and patient outcomes in solid tumors and hematological malignancies. Among the various inhibitory mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e94d084bcd3452e6e52d4fd17c4f8a6
https://doi.org/10.1002/ijc.33415
https://doi.org/10.1002/ijc.33415
Autor:
Marco Maria M. Aiello, Edoardo Migliori, Pushpamali De Silva, Karen Willard-Gallo, Chunyan Gu-Trantien, Cinzia Solinas
Publikováno v:
Critical Reviews in Oncology/Hematology. 142:35-43
Programmed cell death-1 (PD-1) receptor and its ligands physiologically regulate the activity of the adaptive immune system to limit excessive inflammatory processes, thus preventing normal tissue damage. Tumor cells escape from the host immune surve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541fe338a1c66a19a990928a6470fddc
https://doi.org/10.1016/j.critrevonc.2019.07.011
https://doi.org/10.1016/j.critrevonc.2019.07.011
Autor:
Céline Naveaux, Soizic Garaud, Alexandre de Wind, Pushpamali De Silva, Karen Willard-Gallo, Denis Larsimont, Anaïs Boisson, Chunyan Gu-Trantien, Hugues Duvillier, Martine Piccart-Gebhart, Vinu Jose, Cinzia Solinas, Gert Van den Eyden, Ligia Craciun, Edoardo Migliori
Publikováno v:
EBioMedicine
EBioMedicine, 39
EBioMedicine, 39
Background: FOXP1, a transcriptional regulator of lymphocyte development, is abnormally expressed in some human tumors. This study investigated FOXP1-mediated regulation of tumor infiltrating lymphocytes (TIL) in untreated primary breast cancer (BC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbab322614d9797f5acae743f4c951a5
https://doi.org/10.1016/j.ebiom.2018.11.066
https://doi.org/10.1016/j.ebiom.2018.11.066
Publikováno v:
Trends in Immunology. 38:875-878
T follicular helper (TFH) cells are characteristically defined by their CXCR5 positivity and homing to B cell follicles in secondary lymphoid organs (SLO). An expanded subpopulation of functionally comparable and phenotypically similar PD-1hiCXCR5−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0f73180deaed598a4d80f4e60391b55
https://doi.org/10.1016/j.it.2017.10.003
https://doi.org/10.1016/j.it.2017.10.003
Autor:
Karen Willard-Gallo, Chunyan Gu-Trantien, Denis Larsimont, Laurence Buisseret, Jean-Nicolas Lodewyckx, Anaïs Boisson, Marianne Paesmans, Martine Piccart-Gebhart, Cinzia Solinas, Soizic Garaud, Alexandre de Wind, Isabelle Veys, Céline Naveaux, Lieveke Ameye, Gert Van den Eynden, Hughes Duvillier, Ligia Craciun
Publikováno v:
JCI Insight. 4
Tumor-infiltrating B-cells (TIL-B) in breast cancer (BC) have previously been associated with improved clinical outcomes; however, their role(s) in tumor immunity is not currently well known. This study confirms and extends the correlation between hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b2db860c391cf44bf4ce3b8c22ae30
https://doi.org/10.1172/jci.insight.129641
https://doi.org/10.1172/jci.insight.129641
Publikováno v:
ESMO Open
ESMO Open, 5 (1
ESMO Open, 5 (1
Inducible T cell costimulator (ICOS, cluster of differentiation (CD278)) is an activating costimulatory immune checkpoint expressed on activated T cells. Its ligand, ICOSL is expressed on antigen-presenting cells and somatic cells, including tumour c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4ca4a381dd4d930a42c5f3d194c5a1
https://pubmed.ncbi.nlm.nih.gov/32516116
https://pubmed.ncbi.nlm.nih.gov/32516116