Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Chunxiang Yao"'
Autor:
Di Shao, Chunxiang Yao, Maya H. Kim, Jessica Fry, Richard A. Cohen, Catherine E. Costello, Reiko Matsui, Francesca Seta, Mark E. McComb, Markus M. Bachschmid
Publikováno v:
Redox Biology, Vol 22, Iss , Pp - (2019)
Sirtuin-1 (SirT1) catalyzes NAD+-dependent protein lysine deacetylation and is a critical regulator of energy and lipid metabolism, mitochondrial biogenesis, apoptosis, and senescence. Activation of SirT1 mitigates metabolic perturbations associated
Externí odkaz:
https://doaj.org/article/007efb9834d74e2bab6db56ca200aba3
Autor:
Chunxiang Yao, Jessica B Behring, Di Shao, Aaron L Sverdlov, Stephen A Whelan, Aly Elezaby, Xiaoyan Yin, Deborah A Siwik, Francesca Seta, Catherine E Costello, Richard A Cohen, Reiko Matsui, Wilson S Colucci, Mark E McComb, Markus M Bachschmid
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144025 (2015)
Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H2O2), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and
Externí odkaz:
https://doaj.org/article/17226e23b1354d9a9df939a220b367f6
Autor:
Catherine E. Costello, Yu Huang, Jiyang Zhang, Elise E. Drouin, Chunxiang Yao, Allen C. Steere, Deborah R. Leon, Qi Wang
Publikováno v:
Journal of Proteome Research. 16:122-136
HLA-DR-molecules are highly expressed in synovial tissue (ST), the target of the immune response in chronic inflammatory forms of arthritis. Here, we used LC-MS/MS to identify HLA-DR-presented self-peptides in cells taken directly from clinical sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea83aef857c5daf936cb66ce888c209
https://doi.org/10.1021/acs.jproteome.6b00386
https://doi.org/10.1021/acs.jproteome.6b00386
Autor:
Xiuyun Hou, M. Zang, Richard A. Cohen, Peter B. O’Connor, Markus Bachschmid, David R. Pimentel, Rebecca Zee, Chunxiang Yao
Publikováno v:
Free Radical Biology and Medicine. 45:S67-S76
Sirtuin-1 (SIRT1) is an NAD+-dependent histone deacetylase (HDAC) that regulates metabolism. SIRT1 contains a Zn2+ atom coordinated by four cysteines, which is essential for enzyme activity. We hypothesized that the lower pKa of these thiolate center
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a351555ced169217473b23e3a08d66b
https://doi.org/10.1016/j.freeradbiomed.2008.10.011
https://doi.org/10.1016/j.freeradbiomed.2008.10.011
Publikováno v:
International Journal of Mass Spectrometry. 267:30-42
Gas-phase cytosine molecules and cation–radicals represent a complex system of several nearly isoenergetic tautomers within each group. Computational methods differ in ordering the relative enthalpies of neutral cytosine tautomers. At our highest l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff6de76dd5613f08df3d5eec03a1014
https://doi.org/10.1016/j.ijms.2007.02.016
https://doi.org/10.1016/j.ijms.2007.02.016
Publikováno v:
International Journal of Mass Spectrometry. 265:106-123
Cytosine cations were generated by chemical ionization and fast-atom bombardment of cytosine, and their dissociations in the gas phase were studied by tandem mass spectrometry and quantum chemistry calculations at levels of theory up to CCSD(T)/aug-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607ec34e6b5b7492a4f83db872679fcd
https://doi.org/10.1016/j.ijms.2007.01.013
https://doi.org/10.1016/j.ijms.2007.01.013
Autor:
Wilson S. Colucci, Richard J. Cohen, Stephen A. Whelan, Markus Bachschmid, Chunxiang Yao, Christian F. Heckendorf, Jean L. Spencer, Deborah Siwick, Catherine E. Costello, Mark E. McComb, Jessica B. Behring
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c9af250ecfe553b5db39ddcd299f771
https://doi.org/10.1096/fasebj.29.1_supplement.570.21
https://doi.org/10.1096/fasebj.29.1_supplement.570.21
Autor:
Markus Bachschmid, Reiko Matsui, Jessica Fry, Xiang Weng, David R. Pimentel, Chunxiang Yao, Michelle T. Long, Xiuyun Hou, Hemant K. Roy, Jessica B. Behring, Francesca Seta, Di Shao, Richard A. Cohen, Jingyan Han
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2716cdd2a623c8454ce558c35f405fd3
https://doi.org/10.1096/fasebj.29.1_supplement.570.5
https://doi.org/10.1096/fasebj.29.1_supplement.570.5
Pulmonary arterial hypertension (PAH) is a disease characterized by increased pulmonary vascular resistance and remodeling. Increase in the population of vascular smooth muscle cells is among the key events contributing to the remodeling. Endothelin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f165fb90288eec69ef4bcb5c93cea5
https://europepmc.org/articles/PMC4387548/
https://europepmc.org/articles/PMC4387548/
Publikováno v:
Journal of Mass Spectrometry. 40:1417-1428
Tautomers of 1-methylcytosine that are protonated at N-3 (1+) and C-5 (2+) have been specifically synthesized in the gas phase and characterized by tandem mass spectrometry and quantum chemical calculations. Ion 1+ is the most stable tautomer in aque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c4f98f2b1c0feab8c9c648872820b4
https://doi.org/10.1002/jms.923
https://doi.org/10.1002/jms.923