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pro vyhledávání: '"Chuntong Chang"'
Autor:
Craig W. Clarkson, Adrienne Stolfi, Shirou Yamasaki, Chuntong Chang, Arthur S. Pickoff, William J. George
Publikováno v:
Circulation. 87:950-962
BACKGROUND Previous clinical reports have suggested that cocaine intoxication may produce severe ventricular arrhythmias due to a direct effect on the heart. However, the effects of high plasma levels of cocaine on the electrophysiology of the heart
Publikováno v:
Journal of molecular and cellular cardiology. 28(4)
The effects of cocaine on the duration of the cardiac action potential were investigated in isolated guinea-pig ventricular myocytes at 37 degrees C. Following a 10-min exposure of cells to 3 microM cocaine, APD90 increased significantly by +22 +/- 5