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Akademický článek

Multiple valence states of Fe boosting SERS activity of Fe3O4 nanoparticles and enabling effective SERS-MRI bimodal cancer imaging

Autor: Jie Lin, Xuehua Ma, Anran Li, Ozioma Udochukwu Akakuru, Chunshu Pan, Meng He, Chenyang Yao, Wenzhi Ren, Yanying Li, Dinghu Zhang, Yi Cao, Tianxiang Chen, Aiguo Wu

Publikováno v: Fundamental Research, Vol 4, Iss 4, Pp 858-867 (2024)

Developing novel nanoparticle-based bioprobes utilized in clinical settings with imaging resolutions ranging from cell to tissue levels is a major challenge for tumor diagnosis and treatment. Herein, an optimized strategy for designing a Fe3O4-based

Externí odkaz: https://doaj.org/article/3a7b190288164045bc0259ecd447b1db

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Akademický článek

Mn-doped Ti-based MOFs for magnetic resonance imaging-guided synergistic microwave thermal and microwave dynamic therapy of liver cancer

Autor: Qiongyu Qin, Ming Yang, Yu Shi, Haijing Cui, Chunshu Pan, Wenzhi Ren, Aiguo Wu, Jianqing Hu

Publikováno v: Bioactive Materials, Vol 27, Iss , Pp 72-81 (2023)

Currently, precise ablation of tumors without damaging the surrounding normal tissue is still an urgent problem for clinical microwave therapy of liver cancer. Herein, we synthesized Mn-doped Ti MOFs (Mn–Ti MOFs) nanosheets by in-situ doping method

Externí odkaz: https://doaj.org/article/b3ea30ce19ea449b9d5aa6b9fd8eb27a

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Akademický článek

IGF1 receptor-targeted black TiO2 nanoprobes for MRI-guided synergetic photothermal-chemotherapy in drug resistant pancreatic tumor

Autor: Kaiwei Xu, Lufei Jin, Liu Xu, Yuchao Zhu, Lu Hong, Chunshu Pan, Yanying Li, Junlie Yao, Ruifen Zou, Weiwei Tang, Jianhua Wang, Aiguo Wu, Wenzhi Ren

Publikováno v: Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)

Abstract Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignant tumors with features of matrix barrier caused poor drug permeability, and susceptibility to drug resistance. Herein, a PDAC and its stromal cell dual-targeted photother

Externí odkaz: https://doaj.org/article/626119376bfb473c94239ae8bd34a2da

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Akademický článek

Integrated Single-Cell and Transcriptome Sequencing Analyses Develop a Ubiquitination-Associated Signature in Gastric Cancer and Identified OTULIN as a Novel Biomarker

Autor: Zhongting Huang, Zhiyong Zhang, Yangyang Tu, Haibin He, Feng Qiu, Hailong Qian, Chunshu Pan

Publikováno v: Frontiers in Bioscience-Landmark, Vol 28, Iss 11, p 304 (2023)

Background: Gastric cancer (GC) is the most commonly diagnosed digestive system malignancy with a dismal survival outcome. The prognostic value of ubiquitination-related genes (URGs) in GC has yet to be discovered. Methods: Two GC cohort datasets wer

Externí odkaz: https://doaj.org/article/07d0e2f85121402481138412c2d90252

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Akademický článek

Gd2O3/b‐TiO2 composite nanoprobes with ultra‐high photoconversion efficiency for MR image‐guided NIR‐II photothermal therapy

Autor: Jia Chen, Tianxiang Chen, Qianlan Fang, Chunshu Pan, Ozioma Udochukwu Akakuru, Wenzhi Ren, Jie Lin, Aizhu Sheng, Xuehua Ma, Aiguo Wu

Publikováno v: Exploration, Vol 2, Iss 6, Pp n/a-n/a (2022)

Abstract Photothermal therapy (PTT), as an important noninvasive and effective tumor treatment method, has been extensively developed into a powerful cancer therapeutic technique. Nevertheless, the low photothermal conversion efficiency and the limit

Externí odkaz: https://doaj.org/article/8871515004814016ae697d8c9fa28aa8

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