Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chunqiong Li"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractAbnormal accumulation of branched-chain amino acids (BCAAs) can lead to metabolic diseases and cancers. Branched-chain α-keto acid dehydrogenase kinase (BCKDK) is a key negative regulator of BCAA catabolism, and targeting BCKDK provides a pr
Externí odkaz:
https://doaj.org/article/25b42912963b48479ae5338a0038c07a
Publikováno v:
Molecules, Vol 25, Iss 4, p 870 (2020)
Protein kinase (CK2) has emerged as an attractive cancer therapeutic target and recent efforts have been made to develop its inhibitors. However, the development of selective inhibitors remains challenging because of the highly conserved ATP-binding
Externí odkaz:
https://doaj.org/article/c1162cb7f6f843ada0f3227ae4ba155a
Publikováno v:
Molecules, Vol 25, Iss 1, p 237 (2020)
Casein kinase II (CK2) is considered as an attractive cancer therapeutic target, and recent efforts have been made to develop its ATP-competitive inhibitors. However, achieving selectivity with respect to related kinases remains challenging due to th
Externí odkaz:
https://doaj.org/article/2aa6ba95bce04de29f4731c1753ba296
Autor:
Ni A. An, Jie Zhang, Fan Mo, Xuke Luan, Lu Tian, Qing Sunny Shen, Xiangshang Li, Chunqiong Li, Fanqi Zhou, Boya Zhang, Mingjun Ji, Jianhuan Qi, Wei-Zhen Zhou, Wanqiu Ding, Jia-Yu Chen, Jia Yu, Li Zhang, Shaokun Shu, Baoyang Hu, Chuan-Yun Li
Publikováno v:
Nature ecologyevolution.
Human de novo genes can originate from neutral long non-coding RNA (lncRNA) loci and are evolutionarily significant in general, yet how and why this all-or-nothing transition to functionality happens remains unclear. Here, in 74 human/hominoid-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8694325b571605d96fba43577fdb89f4
https://pubmed.ncbi.nlm.nih.gov/36593289
https://pubmed.ncbi.nlm.nih.gov/36593289
Publikováno v:
Molecules, Vol 25, Iss 4, p 870 (2020)
Molecules
Molecules
Protein kinase (CK2) has emerged as an attractive cancer therapeutic target and recent efforts have been made to develop its inhibitors. However, the development of selective inhibitors remains challenging because of the highly conserved ATP-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12248580711718fa79c72447fda83fb5
https://www.mdpi.com/1420-3049/25/4/870
https://www.mdpi.com/1420-3049/25/4/870
Autor:
Zihan Liang, Hu Zhao, Qingjie Zhu, Yi Shao, Li Zhang, Lei Kong, Qingchun Guo, Chunqiong Li, Zhicheng Wang, Xingjun Chen, Mingyue Jia
Publikováno v:
Bioinformatics. 37:3086-3087
Motivation Microscopy technology plays important roles in many biological research fields. Solvent-cleared brain high-resolution (HR) 3D image reconstruction is an important microscopy application. However, 3D microscopy image generation is time-cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a831a68f89c10f6bf18c17d2f13681
https://doi.org/10.1093/bioinformatics/btab144
https://doi.org/10.1093/bioinformatics/btab144
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Benzo [a] pyrene (BaP) in the atmosphere possess great carcinogenic potential to human health, and the understanding of its scavenging mechanisms has attracted considerable attention. In this work, a new quantitative method is proposed to ma
Externí odkaz:
https://doaj.org/article/8bf22d3ab3c942028f23e16ddc4c6bfe
Publikováno v:
Ecological Indicators, Vol 129, Iss , Pp 107877- (2021)
Under combined air pollution conditions, the coordinated control of PM2.5 and O3 has significant implications for environmental management. To better understand the coordinated control capability of different metropolises, a prime consideration is ho
Externí odkaz:
https://doaj.org/article/099cf52b31e3468abc157f9302f432b4
Publikováno v:
Atmosphere, Vol 10, Iss 6, p 331 (2019)
Based on the 19 year observation from 1998 to 2016 at the Tsuan Wan and Central/Western District monitoring stations in Hong Kong, the aim of this paper was to assess the wet deposition pathway of Benzo(a)pyrene (BaP) on a large time-scale. In order
Externí odkaz:
https://doaj.org/article/760cfdb048914942be3fff500d267f14