Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chunqin Chen"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
One pivotal aspect of early pregnancy is decidualization. The decidualization process includes two components: the differentiation of endometrial stromal cells to decidual stromal cells (DSCs), as well as the recruitment and education of decidual imm
Externí odkaz:
https://doaj.org/article/a4b1a072df13468db74ff957aed44476
Autor:
Mengdie Li, Fengrun Sun, Yuanyuan Xu, Lanting Chen, Chunqin Chen, Liyuan Cui, Jinfeng Qian, Dajin Li, Songcun Wang, Meirong Du
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-12 (2022)
Abstract T-cell immunoglobulin mucin-3 (Tim-3) plays roles in the functional regulation of both adaptive and innate immune cells and is greatly involved in many diseases. However, the precise roles of Tim-3 on macrophages (Mφs) in pregnancy remain u
Externí odkaz:
https://doaj.org/article/cb141f1064eb434ebb1810bcbe2ace61
Autor:
Lu Liu, Xixi Huang, Chunfang Xu, Chunqin Chen, Weijie Zhao, Dajin Li, Liping Li, Li Wang, Meirong Du
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background During early pregnancy, tolerance of the semi-allogeneic fetus necessitates comprehensive modifications of the maternal immune system. How decidual CD8+T (CD8+dT) cells balance maternal tolerance of the fetus with defense from inv
Externí odkaz:
https://doaj.org/article/2413616906cd4509adf26270d24a72d8
Autor:
Fengrun Sun, Liyuan Cui, Jinfeng Qian, Mengdie Li, Lanting Chen, Chunqin Chen, Dajin Li, Songcun Wang, Meirong Du
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7836
Iron is necessary for various critical biological processes, but iron overload is also dangerous since labile iron is redox-active and toxic. We found that low serum iron and decidual local iron deposition existed simultaneously in recurrent pregnanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e2b5f1601644a7b5acefbf6ad06275
Autor:
Xiandong Peng, Meirong Du, Jian-Ping Zhang, Jinfeng Qian, Songcun Wang, Chunqin Chen, Fengrun Sun, Meng-Die Li
Publikováno v:
Reproduction. 161:1-10
To obtain a successful pregnancy, trophoblasts must provide a physical barrier, suppress maternal reactivity, produce immunosuppressive hormones locally, and enhance the production of blocking factors that are able to bind to several antigenic sites.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3bfdf70eb877bd3cf33d2ac1b17c7d5
https://doi.org/10.1530/rep-19-0543
https://doi.org/10.1530/rep-19-0543
Autor:
Weijie Zhao, Xixi Huang, Li Wang, Lu Liu, Meirong Du, Chunfang Xu, Liping Li, Da-Jin Li, Chunqin Chen
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Journal of Translational Medicine
Journal of Translational Medicine
Background During early pregnancy, tolerance of the semi-allogeneic fetus necessitates comprehensive modifications of the maternal immune system. How decidual CD8+T (CD8+dT) cells balance maternal tolerance of the fetus with defense from invading pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1478680b2e0a9846e1c0a4330c2891aa
http://link.springer.com/article/10.1186/s12967-020-02371-3
http://link.springer.com/article/10.1186/s12967-020-02371-3
Autor:
Mengdie, Li, Fengrun, Sun, Yuanyuan, Xu, Lanting, Chen, Chunqin, Chen, Liyuan, Cui, Jinfeng, Qian, Dajin, Li, Songcun, Wang, Meirong, Du
Publikováno v:
Cell deathdisease. 13(5)
T-cell immunoglobulin mucin-3 (Tim-3) plays roles in the functional regulation of both adaptive and innate immune cells and is greatly involved in many diseases. However, the precise roles of Tim-3 on macrophages (Mφs) in pregnancy remain unstated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77e6fae6a7119eee1e39ad91e0be7c29
https://pubmed.ncbi.nlm.nih.gov/35550500
https://pubmed.ncbi.nlm.nih.gov/35550500
Autor:
Min Yu, Da-Jin Li, Chunqin Chen, Xingxing Zang, Mengdie Li, Mingyan Wang, Fengrun Sun, Meirong Du, Jinfeng Qian, Songcun Wang
Publikováno v:
Cell Death and Disease, Vol 10, Iss 6, Pp 1-11 (2019)
Cell Death & Disease
Cell Death & Disease
Maternal decidual CD8+ T (dCD8+ T) cells must integrate the antithetical demands of maternal–fetal tolerance and anti-viral immunity to establish a successful pregnancy. T-cell immunoglobulin mucin-3 (Tim-3) and cytotoxic T-lymphocyte-associated pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f46a0c47bc2130a49f4bee4ba684e10
http://link.springer.com/article/10.1038/s41419-019-1642-x
http://link.springer.com/article/10.1038/s41419-019-1642-x
Autor:
Jinfeng Qian, Chunqin Chen, Jiangfeng Ye, Songcun Wang, Meirong Du, Fengrun Sun, Mengdie Li, Da-Jin Li
Publikováno v:
Biology of Reproduction. 104:410-417
Normal pregnancy is associated with several immune adaptations in both systemic and local maternal–fetal interface to allow the growth of semi-allogeneic conceptus. A failure in maternal immune tolerance to the fetus may result in abnormal pregnanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57c539bd9dd72726b28a51bc46fa775
https://doi.org/10.1093/biolre/ioz076
https://doi.org/10.1093/biolre/ioz076
Autor:
Meirong Du, Min Yu, Jinfeng Qian, Songcun Wang, Yunyun Li, Xingxing Zang, Chunqin Chen, Da-Jin Li, Mingyan Wang, Mengdie Li, Rui Zhu, Fengyun Sun
Publikováno v:
Cell Death and Disease, Vol 10, Iss 1, Pp 1-10 (2019)
Cell Death & Disease
Cell Death & Disease
The single and/or combination use of immune checkpoint blockade therapies in human infectious diseases and cancer are rapidly expanding. Despite early efforts, substantial uncertainty remains about the safety and efficacy of immune checkpoint blockad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965cb617c70253d2fd6448d89f8ee527
http://link.springer.com/article/10.1038/s41419-018-1251-0
http://link.springer.com/article/10.1038/s41419-018-1251-0