Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Chunping Qiao"'
Autor:
Alexander W.M. Hooper, Hayes Wong, Yosuke Niibori, Rozita Abdoli, Subha Karumuthil-Melethil, Chunping Qiao, Olivier Danos, Joseph T. Bruder, David R. Hampson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 196-209 (2021)
Fragile X syndrome (FXS), a neurodevelopmental disorder with no known cure, is caused by a lack of expression of the fragile X mental retardation protein (FMRP). As a single-gene disorder, FXS is an excellent candidate for viral-vector-based gene the
Externí odkaz:
https://doaj.org/article/39f2762e4bc2409e975a474aed179042
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Abstract Background Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor β superfamily. The GDF11 propeptide, which is derived from the GDF11 precursor protein, blocks the activity of GDF11 and its homolog, myostati
Externí odkaz:
https://doaj.org/article/1d7f59335c5a405f9e9be7fc4301ae42
Autor:
Karen Bulaklak, Bin Xiao, Chunping Qiao, Jianbin Li, Tejash Patel, Quan Jin, Juan Li, Xiao Xiao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 283-293 (2018)
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disorder caused by a mutation in the dystrophin gene. Numerous gene therapies have been developed to replace or repair the defective dystrophin gene; however, these treatments cannot restor
Externí odkaz:
https://doaj.org/article/b88b5203443441828752d793c23e8966
Autor:
Chunping Qiao, Yi Dai, Viktoriya D. Nikolova, Quan Jin, Jianbin Li, Bin Xiao, Juan Li, Sheryl S. Moy, Xiao Xiao
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 47-56 (2018)
LAMA2-related muscular dystrophy (LAMA2 MD) is the most common and fatal form of early-onset congenital muscular dystrophies. Due to the large size of the laminin α2 cDNA and heterotrimeric structure of the protein, it is challenging to develop a ge
Externí odkaz:
https://doaj.org/article/6a279e4c8d194810bc744e9f65427a32
Autor:
Rozita Abdoli, Subha Karumuthil-Melethil, Yosuke Niibori, Alexander W.M. Hooper, David R. Hampson, Olivier Danos, Hayes Wong, Chunping Qiao, Joseph T. Bruder
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 196-209 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 196-209 (2021)
Fragile X syndrome (FXS), a neurodevelopmental disorder with no known cure, is caused by a lack of expression of the fragile X mental retardation protein (FMRP). As a single-gene disorder, FXS is an excellent candidate for viral-vector-based gene the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bc7c918cc34d19f59dd4201f282537
https://doi.org/10.1016/j.omtm.2021.06.013
https://doi.org/10.1016/j.omtm.2021.06.013
Autor:
Xiao Xiao, Hongbo You, Juan Li, Bing Wang, Xiangyu Chu, Jing Wang, Yiqing Wang, Xian-Cheng Jiang, Chunping Qiao
Publikováno v:
The FASEB Journal. 35
Duchenne muscular dystrophy (DMD) is a lethal genetic muscle disorder caused by recessive mutations in dystrophin gene, affecting 1/3000 males. Gene therapy has been proven to ameliorate dystrophic pathology. To investigate therapeutic benefits from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5d7cd4d7f8d98d05929f0b50f15693
https://doi.org/10.1096/fj.202100057rr
https://doi.org/10.1096/fj.202100057rr
Autor:
Lina Li, Emilios K Dimitriadis, Yu Yang, Juan Li, Zhenhua Yuan, Chunping Qiao, Cyriaque Beley, Richard H Smith, Luis Garcia, Robert M Kotin
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69879 (2013)
Conventional non-viral gene transfer uses bacterial plasmid DNA containing antibiotic resistance genes, cis-acting bacterial sequence elements, and prokaryotic methylation patterns that may adversely affect transgene expression and vector stability i
Externí odkaz:
https://doaj.org/article/56fddd23d35942e280a4e9ab2fd344c4
Autor:
Sheryl S. Moy, Juan Li, Chunping Qiao, Jianbin Li, Bin Xiao, Viktoriya D. Nikolova, Xiao Xiao, Quan Jin, Yi Dai
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 47-56 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
LAMA2-related muscular dystrophy (LAMA2 MD) is the most common and fatal form of early-onset congenital muscular dystrophies. Due to the large size of the laminin α2 cDNA and heterotrimeric structure of the protein, it is challenging to develop a ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac71492d5dff92a331e39cb0e7d3d7ae
https://doi.org/10.1016/j.omtm.2018.01.005
https://doi.org/10.1016/j.omtm.2018.01.005
Publikováno v:
Molecular Therapy. 26:1109-1117
Growth and differentiation factor 11 (GDF11; BMP11) is a circulating cytokine in the transforming growth factor beta (TGF-β) superfamily. Treatment with recombinant GDF11 (rGDF11) protein has previously been shown to reverse skeletal muscle dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171ad891cc2cb059fb704b4144178811
https://doi.org/10.1016/j.ymthe.2018.01.016
https://doi.org/10.1016/j.ymthe.2018.01.016
Recombinant adeno-associated viral (AAV) vectors are frequently used to deliver nucleic acids for in vivo applications and are currently the leading platform for therapeutic gene delivery in gene therapy clinical trials. Presently, there is a need fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea54474d92ebcc1e996e6ad038d43734
