Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Chunmei Ji"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundEnfortumab vedotin (EV) is an antibody-drug conjugate (ADC) that has been approved by the FDA for patients with locally advanced or metastatic urothelial carcinoma (UC). This study presents a comprehensive pharmacovigilance analysis of the
Externí odkaz:
https://doaj.org/article/e53ad0a8eb1b43eb974fb0cc0661713e
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Apalutamide is a new drug class, which is approved to treat prostate cancer (PCa). The aim of our study was to assess the safety profiles of apalutamide in real-world through data mining of the United States Food and Drug Administration A
Externí odkaz:
https://doaj.org/article/9d981f49dbab499a871dded1017d3d49
Autor:
Yunzhen Hu, Chunmei Ji
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background The efficacy and safety of intravenous thrombolysis (IVT) for acute ischemic stroke with atrial fibrillation (AF) is still controversial. Methods We conducted a meta-analysis of all relevant studies, retrieved through systematic s
Externí odkaz:
https://doaj.org/article/ac19ac63413740a29f4a41e963b4f713
Autor:
Neha Dixit, Christie Fanton, John L. Langowski, Yolanda Kirksey, Peter Kirk, Thomas Chang, Janet Cetz, Vidula Dixit, Grace Kim, Peiwen Kuo, Mekhala Maiti, Yinyan Tang, Laurie A. VanderVeen, Ping Zhang, Myong Lee, Jerome Ritz, Yusuke Kamihara, Chunmei Ji, Werner Rubas, Theresa D. Sweeney, Stephen K. Doberstein, Jonathan Zalevsky
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100103- (2021)
Impaired interleukin-2 (IL-2) production and regulatory T-cell dysfunction have been implicated as immunological mechanisms central to the pathogenesis of multiple autoimmune and inflammatory diseases. NKTR-358, a novel regulatory T-cell stimulator,
Externí odkaz:
https://doaj.org/article/63812ff90adf4c7e9449ec1fa8aa92e5
Publikováno v:
BMC Health Services Research, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Limited studies have evaluated the effectiveness of pharmacist interventions on outpatient prescription. The goal of this study was to evaluate the clinical and economic impacts of pharmacist interventions on randomly sampled outp
Externí odkaz:
https://doaj.org/article/bcbc0ec54ed641ec826fb3ced5ce880c
IMPROVING SEMANTIC ANALYSIS IN VISUALIZATION WITH META NETWORK REPRESENTATION AND PARSING ALGORITHM.
Publikováno v:
Scalable Computing: Practice & Experience; Jan2024, Vol. 25 Issue 1, p75-84, 10p
Publikováno v:
British Journal of Clinical Pharmacology. 88:5317-5325
Proprotein convertase subtilisin/kexin type (PCSK9) inhibitor is a new drug class approved for treating dyslipidemias. Herein, we aimed to investigate the safety profiles of PCSK9 inhibitors (alirocumab and evolocumab) using the Food and Drug Adminis
Autor:
Stephen K. Doberstein, Seema S. Kantak, Theresa D. Sweeney, Jicai Huang, Yujun Wang, Chunmei Ji, Yolanda M. Kirksey, Rupesh S. Kanhere, Rhoneil L. Pena, Marina Konakova, Thomas K. Chang, Cherie F. Ali, Laurie A. VanderVeen, Paul W. Sims, Xiaofeng Liu, Dawei Sheng, Peter B. Kirk, Murali K. Addepalli, Steve R. Lee, John L. Langowski, Ute Hoch, Deborah H. Charych
Binding curves from surface plasmon resonance studies of purified active 1-PEG-IL-2 released from NKTR-214 binding to IL-2Rαβ and IL-2Rβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134c32d3a79528e455bdc621b359c574
https://doi.org/10.1158/1078-0432.22460627.v1
https://doi.org/10.1158/1078-0432.22460627.v1
Autor:
Stephen K. Doberstein, Seema S. Kantak, Theresa D. Sweeney, Jicai Huang, Yujun Wang, Chunmei Ji, Yolanda M. Kirksey, Rupesh S. Kanhere, Rhoneil L. Pena, Marina Konakova, Thomas K. Chang, Cherie F. Ali, Laurie A. VanderVeen, Paul W. Sims, Xiaofeng Liu, Dawei Sheng, Peter B. Kirk, Murali K. Addepalli, Steve R. Lee, John L. Langowski, Ute Hoch, Deborah H. Charych
Purpose: Aldesleukin, recombinant human IL2, is an effective immunotherapy for metastatic melanoma and renal cancer, with durable responses in approximately 10% of patients; however, severe side effects limit maximal dosing and thus the number of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fe8117f5e79650581c47831ffd8438
https://doi.org/10.1158/1078-0432.c.6524552
https://doi.org/10.1158/1078-0432.c.6524552
Autor:
Stephen K. Doberstein, Seema S. Kantak, Theresa D. Sweeney, Jicai Huang, Yujun Wang, Chunmei Ji, Yolanda M. Kirksey, Rupesh S. Kanhere, Rhoneil L. Pena, Marina Konakova, Thomas K. Chang, Cherie F. Ali, Laurie A. VanderVeen, Paul W. Sims, Xiaofeng Liu, Dawei Sheng, Peter B. Kirk, Murali K. Addepalli, Steve R. Lee, John L. Langowski, Ute Hoch, Deborah H. Charych
Supplemental Materials and Methods. ELISA study materials; NKTR-214 chemistry; Mapping of PEGylation sites; Identification of active released IL-2 conjugates; Binding affinity to IL-2 receptors; In vivo immune cell phenotyping, In vivo immune cell ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0355aa629ebbad4322a3a47b80293276
https://doi.org/10.1158/1078-0432.22460618
https://doi.org/10.1158/1078-0432.22460618