Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chunlong Cai"'
Publikováno v:
ACS Agricultural Science & Technology. 1:222-229
Our previous investigation revealed that phenanthroindolizidine alkaloid derivatives have a good inhibitory effect against tabacco mosaic virus (TMV) and that the conformation of these alkaloid ana...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::713044ddc848534418afbafed17eeee9
https://doi.org/10.1021/acsagscitech.1c00032
https://doi.org/10.1021/acsagscitech.1c00032
Autor:
Wietfeld Bernhard, Xiangguang Tian, Yong Zhang, Franck Mallet, Richard Kaehny, Cheng Li, Leo A. Hardegger, Bo Yu, Jeannine Stäuble, Lei Shi, Barbara Bianchi, Florian Andreas Rampf, Jialiang Li, Stephan Lanz, Christoph Spoendlin, Christine Zepperitz, Xuesong Zhang, Shangjun Teng, Chunlong Cai, Yao Yang, Roger Humair, Alexandre Grand-Guillaume Perrenoud
Publikováno v:
Organic Process Research & Development. 24:1743-1755
We present the enantioselective synthesis of sodium (3S)-5-(benzyloxy)-2-(diphenylacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (EMA401, olodanrigan), an angiotensin II type 2 anta...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae16af12c7d788634acb2f52287a02f
https://doi.org/10.1021/acs.oprd.0c00215
https://doi.org/10.1021/acs.oprd.0c00215
Publikováno v:
Journal of Agricultural and Food Chemistry. 64:2039-2045
Our recent investigation on the antiviral activities against tobacco mosaic virus (TMV) of phenanthroindolizidine alkaloid analogues preliminarily revealed that the basic skeleton and substitution pattern at the C13a position of the molecule, which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea255b9f4e109dba2b8d01e1d0293050
https://doi.org/10.1021/acs.jafc.5b06112
https://doi.org/10.1021/acs.jafc.5b06112
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(13)
On the basis of our previous structure-activity relationship (SAR) and antiviral mechanism studies, a series of 13a-substituted phenanthroindolizidine alkaloid analogues (3a-16a, 3b, 4b, 6b, 7b, 10b, and 14b) were designed targeting tobacco mosaic vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e524c2ad3d60437d14ac3f67343c0860
https://pubmed.ncbi.nlm.nih.gov/24835986
https://pubmed.ncbi.nlm.nih.gov/24835986
Publikováno v:
ChemInform. 44
The key steps are stereoselective alkylation of the bromides (I) and Pictet—Spengler cyclization of the amines (V).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f9c67b39c6d47a63ad6173a2ad7b654
https://doi.org/10.1002/chin.201303180
https://doi.org/10.1002/chin.201303180
Publikováno v:
The Journal of organic chemistry. 77(18)
The first enantioselective approach to 13a-methylphenanthroindolizidine alkaloids is reported, featuring an efficient stereoselective Seebach’s alkylation and Pictet–Spengler cyclization. The proposed and other three most probable structures were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b02a726e3e096dfdd4064daa6fc88a
https://pubmed.ncbi.nlm.nih.gov/22946502
https://pubmed.ncbi.nlm.nih.gov/22946502
Publikováno v:
Journal of Agricultural & Food Chemistry; 3/16/2016, Vol. 64 Issue 10, p2039-2045, 7p
Publikováno v:
Journal of Organic Chemistry; 9/21/2012, Vol. 77 Issue 18, p7981-7987, 7p