Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chunle Wei"'
Autor:
Xiong Yang, Deguo Liu, Chunle Wei, Jianzhuan Li, Chunni Zhao, Yanping Tian, Xiangdong Li, Baoan Song, Runjiang Song
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111210- (2024)
Summary: Although the determination of the structural basis of potato virus Y (PVY) coat protein (CP) provides the possibility for CP-based antiviral drug design, the role of many specific residues on CP in regulating virion pathogenicity is largely
Externí odkaz:
https://doaj.org/article/336f7e50516543a899305fe676ff4039
Publikováno v:
Advanced Science, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract The control of potato virus Y (PVY) induced crop failure is a challengeable issue in agricultural chemistry. Although many anti‐PVY agents are designed to focus on the functionally important coat protein (CP) of virus, how these drugs act
Externí odkaz:
https://doaj.org/article/8bd30dafd3544e84b9f530ce21565d7f
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:7239-7249
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:267-275
3-Hydroxy-2-oxindole motif constitutes a core structure in numerous natural products and imparts notable biological activities. Here, we describe the design and synthesis of four series of novel 3-substituted-3-hydroxy-2-oxindole derivatives containi
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8280
In this study, a commercial agent with antivirus activity and moroxydine hydrochloride were employed to perform a lead optimization. A series of 1,3,5-triazine derivatives with piperazine structures were devised and synthesized, and an evaluation of
Publikováno v:
Journal of agricultural and food chemistry. 70(23)
Quinoxaline and its derivatives are important functional molecules with a broad range of applications. Disclosed here is a design and synthesis of a series of novel quinoxaline derivatives containing dithioacetal moieties as well as their antiviral a
Publikováno v:
Journal of agricultural and food chemistry. 70(19)
Cucumber mosaic virus (CMV) is currently a known plant virus with the most hosts, broadest distribution, and economic hazard. To develop new antiviral drugs against this serious virus, a new range of coumarin derivatives containing sulfonamide and di
Publikováno v:
Journal of Agricultural and Food Chemistry. 67:13882-13891
A series of compounds with potential activity to induce plant resistance was synthesized from indole and thiol compounds and methodically evaluated for antiviral activity. The results indicated that some of the synthesized compounds had high antipota
Publikováno v:
Journal of agricultural and food chemistry. 68(4)
In this study, a series of coumarin derivatives containing dithioacetals were synthesized, characterized, and assessed for their anti-tobacco mosaic virus (TMV) activities. Biological tests showed that most of the title compounds exhibited significan
Publikováno v:
Pesticide Biochemistry and Physiology. 167:104605
On the basis of the active substructure combination principle, 24 novel synthesis of novel bis-sulfoxide derivatives bearing acylhydrazone and benzothiazole moieties as potential antibacterial agents were designed and synthesized. The bioactivity ass