Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Chunhe Wang"'
Autor:
Hongxiang Ji, Hualin Sun, Yinghui Zhang, Ziyi Zhao, Xin Gao, Chunhe Wang, Yang Yang, Xiaodong Zhang, Jianyong Gao, Dequan Man, Qian Yang, Ying Yang, Chengbin Yue, Changjiang Chen, Xiaoheng Ding, Tongshang Ni
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
AimTo evaluate the real-life effectiveness and safety of hydrogen inhalation (HI) therapy as an additional treatment in Chinese adults with hypertension.MethodsThis observational, retrospective clinical study included hypertensive patients receiving
Externí odkaz:
https://doaj.org/article/2faa1c71bc2e4e2cad5b0411fb9ef5be
Autor:
Dandan Jin, Haoyi Yang, Zhiyou Chen, Yuxin Hong, Hehua Ma, Zhenzhen Xu, Bei Cao, Fei Fei, Yuwen Zhang, Weitao Wu, Lei Tang, Runbin Sun, Chunhe Wang, Juan Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The anti-nerve growth factor antibody class of drugs interrupts signaling by blocking NGF binding to TrkA receptors for the treatment of pain; however, this target class of drugs has been associated with serious adverse effects in the joints during c
Externí odkaz:
https://doaj.org/article/9b17ec2d6e504cca8c0077f40b491cbd
Autor:
Yongmei Wang, Yi-Li Chen, Hui Xu, Gul E. Rana, Xiaorong Tan, Mengying He, Qingqing Jing, Qi Wang, Guifeng Wang, Zuoquan Xie, Chunhe Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHumanization is typically adopted to reduce the immunogenicity of murine antibodies generated by hybridoma technology when used in humans.MethodsTwo different strategies of antibody humanization are popularly employed, including “comple
Externí odkaz:
https://doaj.org/article/4de509a4348b4b1e9ee265d2f6b70fc5
Publikováno v:
Applied Sciences, Vol 14, Iss 5, p 1858 (2024)
To study the phenomenon of large deformation and the failure of roadways under dynamic pressure, this paper takes the 10607 gas drainage roadway as the research object and presents the results of a theoretical derivation of equations for the boundary
Externí odkaz:
https://doaj.org/article/18cfd2d1f5ce4026b17de55d9cef08ac
Autor:
Renliang Shan, Zhaolong Li, Chunhe Wang, Chi Meng, Yonghui Wei, Yongzhen Li, Xiao Tong, Dong Liu
Publikováno v:
Energy Science & Engineering, Vol 10, Iss 8, Pp 2756-2771 (2022)
Abstract To analyze the plastic failure process and mechanism of gob floor in the process of close‐distance coal seams mining, a simplified mechanical model of the lateral abutment pressure of the gob was proposed to derive the stress of surroundin
Externí odkaz:
https://doaj.org/article/81ec5451d36d49f1bffde569e5e944b1
Autor:
Xingchen Dong, Huanhuan Li, Min Pei, Jie Tan, Ganjun Chen, Santai Li, Zuobin Xie, Qi Wang, Guifeng Wang, Yi‐Li Chen, Chunhe Wang
Publikováno v:
FEBS Open Bio, Vol 12, Iss 7, Pp 1325-1335 (2022)
Current treatment options for diabetic neuralgia are limited and unsatisfactory. Tanezumab, a monoclonal antibody that blocks nerve growth factor (NGF) signaling, has been shown to be effective in relieving the clinical symptoms of osteoarthritis pai
Externí odkaz:
https://doaj.org/article/a9606ba2735548999bd7b89e87cd8e56
Autor:
Tingting Ma, Bei Cao, Lei Huang, Yuanxun Yang, Yan Geng, Pinhao Xie, Yu Zhao, Hui Lin, Kun Wang, Chunhe Wang, Runbin Sun, Juan Li
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Purpose: To evaluate the safety, tolerability, pharmacokinetics and immunogenicity of DS002 injection, an anti-nerve growth factor (anti-NGF) monoclonal antibody for treating pain conditions, in healthy Chinese subjects.Methods: This study was a sing
Externí odkaz:
https://doaj.org/article/a5cc87f1d96144faa796463962b53df9
Publikováno v:
Bio-Protocol, Vol 12, Iss 19 (2022)
Bispecific antibodies (BsAbs) are typically monoclonal antibody (mAb)–derived molecular entities engineered to bind to two distinct targets, including two antigens or two epitopes on the same antigen. When compared to parental monoclonal antibodies
Externí odkaz:
https://doaj.org/article/aa411534004741f891589d5d69b7e8ee
Autor:
Yuning Chen, Ya-Nan Zhang, Renhong Yan, Guifeng Wang, Yuanyuan Zhang, Zhe-Rui Zhang, Yaning Li, Jianxia Ou, Wendi Chu, Zhijuan Liang, Yongmei Wang, Yi-Li Chen, Ganjun Chen, Qi Wang, Qiang Zhou, Bo Zhang, Chunhe Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract The evolution of coronaviruses, such as SARS-CoV-2, makes broad-spectrum coronavirus preventional or therapeutical strategies highly sought after. Here we report a human angiotensin-converting enzyme 2 (ACE2)-targeting monoclonal antibody, 3
Externí odkaz:
https://doaj.org/article/35219e6c1dc04f9e9c101622932521d1
Autor:
Jianxia Ou, Yanan Zhang, Yongmei Wang, Zherui Zhang, Hongping Wei, Junping Yu, Qi Wang, Guifeng Wang, Bo Zhang, Chunhe Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/9a4c88e96e27420e8861b2575a6f2aee