Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Chungyu Chang"'
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT During pilus assembly within the Gram-positive bacterial envelope, membrane-bound sortase enzymes sequentially crosslink specific pilus protein monomers through their cell wall sorting signals (CWSS), starting with a designated tip pilin, fo
Externí odkaz:
https://doaj.org/article/8a4a8ab936ed46f2b8ac6016a2305ee0
Autor:
Wei Chen, Sharon Y. Kim, Alicia Lee, Yun-Jeong Kim, Chungyu Chang, Hung Ton-That, Reuben Kim, Sangjae Kim, No-Hee Park
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6126 (2024)
GV1001, an anticancer vaccine, exhibits other biological functions, including anti-inflammatory and antioxidant activity. It also suppresses the development of ligature-induced periodontitis in mice. Porphyromonas gingivalis (Pg), a major human oral
Externí odkaz:
https://doaj.org/article/29c273ca772d4ca98aec9c31675a5401
Autor:
Yi-Wei Chen, Martha I. Camacho, Yimin Chen, Aadil H. Bhat, Chungyu Chang, Emily A. Peluso, Chenggang Wu, Asis Das, Hung Ton-That
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT The Gram-negative anaerobe Fusobacterium nucleatum is a major producer of hydrogen sulfide (H2S), a volatile sulfur compound that causes halitosis. Here, we dissected the genetic determinants of H2S production and its role in bacterial fitne
Externí odkaz:
https://doaj.org/article/e47cce43b48742f2972a240849ab12b5
Autor:
Matthew Scheible, Cuong T. Nguyen, Truc Thanh Luong, Ju Huck Lee, Yi-Wei Chen, Chungyu Chang, Manuel Wittchen, Martha I. Camacho, Bethany L. Tiner, Chenggang Wu, Andreas Tauch, Asis Das, Hung Ton-That
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Fusobacterium nucleatum, an anaerobic Gram-negative bacterium frequently found in the human oral cavity and some extra-oral sites, is implicated in several important diseases: periodontitis, adverse pregnancy outcomes, and colorectal cancer.
Externí odkaz:
https://doaj.org/article/b73cb6181f5f4f71bab115251d5e506d
Autor:
Truc Thanh Luong, Minh Tan Nguyen, Yi-Wei Chen, Chungyu Chang, Ju Huck Lee, Manuel Wittchen, HyLam Ton-That, Melissa Cruz, Danielle A. Garsin, Asis Das, Andreas Tauch, Hung Ton-That
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 389 (2021)
Controlled RNA degradation is a crucial process in bacterial cell biology for maintaining proper transcriptome homeostasis and adaptation to changing environments. mRNA turnover in many Gram-positive bacteria involves a specialized ribonuclease calle
Externí odkaz:
https://doaj.org/article/202e6fe559b04a48919b9efcb3633829
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT The Gram-positive actinobacteria Actinomyces spp. are key colonizers in the development of oral biofilms due to the inherent ability of Actinomyces to adhere to receptor polysaccharides on the surface of oral streptococci and host cells. Thi
Externí odkaz:
https://doaj.org/article/f48ef6f9d652423781d66a49c8f78128
Autor:
Jouko Sillanpää, Chungyu Chang, Kavindra V Singh, Maria Camila Montealegre, Sreedhar R Nallapareddy, Barrett R Harvey, Hung Ton-That, Barbara E Murray
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68813 (2013)
The endocarditis and biofilm-associated pilus (Ebp) operon is a component of the core genome of Enterococcus faecalis that has been shown to be important for biofilm formation, adherence to host fibrinogen, collagen and platelets, and in experimental
Externí odkaz:
https://doaj.org/article/d83ff078cac643e0aa633efc3252400e
Autor:
Chungyu Chang1, Ton-That, HyLam2, Osipiuk, Jerzy3,4, Joachimiak, Andrzej3,4,5, Das, Asis6, Hung Ton-That1,7,8 htonthat@dentistry.ucla.edu
Publikováno v:
Journal of Biological Chemistry. Jun2024, Vol. 300 Issue 6, p1-14. 14p.
Autor:
Christopher K. Sue, Nicole A. Cheung, Brendan J. Mahoney, Scott A. McConnell, Jack M. Scully, Janine Y. Fu, Chungyu Chang, Hung Ton-That, Joseph A. Loo, Robert T. Clubb
Publikováno v:
bioRxiv
Many species of pathogenic gram-positive bacteria display covalently crosslinked protein polymers (called pili or fimbriae) that mediate microbial adhesion to host tissues. These structures are assembled by pilus-specific sortase enzymes that join th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206654ed6d28a52e3139e686c80ebd96
https://europepmc.org/articles/PMC9980135/
https://europepmc.org/articles/PMC9980135/
Autor:
Melissa E. Reardon-Robinson, Minh Tan Nguyen, Belkys C. Sanchez, Jerzy Osipiuk, Christian Rückert, Chungyu Chang, Bo Chen, Rahul Nagvekar, Andrzej Joachimiak, Andreas Tauch, Asis Das, Hung Ton-That
Publikováno v:
Proceedings of the National Academy of Sciences. 120
In many gram-positive Actinobacteria, including Actinomyces oris and Corynebacterium matruchotii , the conserved thiol-disulfide oxidoreductase MdbA that catalyzes oxidative folding of exported proteins is essential for bacterial viability by an unid