Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Chung-ke Chang"'
Autor:
Chung-ke Chang, Shan-Meng Lin, Roshan Satange, Shih-Chao Lin, Sin-Cih Sun, Hung-Yi Wu, Kylene Kehn-Hall, Ming-Hon Hou
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2246-2255 (2021)
To date, the COVID-19 pandemic has claimed over 1 million human lives, infected another 50 million individuals and wreaked havoc on the global economy. The crisis has spurred the ongoing development of drugs targeting its etiological agent, the SARS-
Externí odkaz:
https://doaj.org/article/1eabc8bf7e714638a8ac05816e4a0a1d
Autor:
Ming-Wei Su, Chung-Ke Chang, Chien-Wei Lin, Shiu-Jie Ling, Chia-Ni Hsiung, Hou-Wei Chu, Pei-Ei Wu, Chen-Yang Shen
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229922 (2020)
Diabetes, dyslipidemia and hypertension are important metabolic diseases that impose a great burden on many populations worldwide. However, certain population strata have reduced prevalence for all three diseases, but the underlying mechanisms are po
Externí odkaz:
https://doaj.org/article/547d102859864d9db8c4687d91dffee6
Autor:
Ming-Wei Su, Chung-Ke Chang, Chien-Wei Lin, Hou-Wei Chu, Tsen-Ni Tsai, Wei-Chih Su, Yen-Cheng Chen, Tsung-Kun Chang, Ching-Wen Huang, Hsiang-Lin Tsai, Chang-Chieh Wu, Huang-Chi Chou, Bei-Hao Shiu, Jaw-Yuan Wang
Publikováno v:
Cells, Vol 11, Iss 3, p 527 (2022)
Colorectal cancer (CRC) is the third most common cancer worldwide. The incidence and mortality rates of CRC are significantly higher in Taiwan than in other developed countries. Genes involved in CRC tumorigenesis differ depending on whether the tumo
Externí odkaz:
https://doaj.org/article/83c45feb64b14b88bc76e3f10488e1c7
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65045 (2013)
The nucleocapsid (N) phosphoprotein of the severe acute respiratory syndrome coronavirus (SARS-CoV) packages the viral genome into a helical ribonucleocapsid and plays a fundamental role during viral self-assembly. The N protein consists of two struc
Externí odkaz:
https://doaj.org/article/64fa5c5d3dc74897b2f88cedb00a6ce2
Autor:
Sin-Cih Sun, Roshan Satange, Shan-Meng Lin, Hung-Yi Wu, Chung-ke Chang, Ming-Hon Hou, Shih-Chao Lin, Kylene Kehn-Hall
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2246-2255 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2246-2255 (2021)
To date, the COVID-19 pandemic has claimed over 1 million human lives, infected another 50 million individuals and wreaked havoc on the global economy. The crisis has spurred the ongoing development of drugs targeting its etiological agent, the SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9049484dd5bced880fa3b4149ae88d1f
http://europepmc.org/articles/PMC8064971
http://europepmc.org/articles/PMC8064971
Autor:
Hung-Yi Wu, Yong Sheng Wang, Ching-Ming Chien, U-Ser Jeng, Kylene Kehn-Hall, Shih-Chao Lin, Chung-ke Chang, Ming-Hon Hou, Jia-Ning Hsu, Shan-Meng Lin
Publikováno v:
Journal of Medicinal Chemistry
Structure-based stabilization of protein–protein interactions (PPIs) is a promising strategy for drug discovery. However, this approach has mainly focused on the stabilization of native PPIs, and non-native PPIs have received little consideration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3fd9b91c3c9273214d10a8ceedc315
https://doi.org/10.1021/acs.jmedchem.9b01913
https://doi.org/10.1021/acs.jmedchem.9b01913
Autor:
Abdul-Hamid M. Emwas, Chung-ke Chang, Mariusz Jaremko, Ryan T. McKay, Joanna Izabela Lachowicz, Hiba Asfour, Kacper Szczepski
Pharmacology is the predominant first-line treatment for most pathologies. However, various factors, such as genetics, gender, diet, and health status, significantly influence the efficacy of drugs in different patients, sometimes with fatal conseque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49e9e79dafc1b47d1dbe441d76e1e6b
http://www.intechopen.com/articles/show/title/pharmacometabolomics-a-new-horizon-in-personalized-medicine
http://www.intechopen.com/articles/show/title/pharmacometabolomics-a-new-horizon-in-personalized-medicine
Autor:
Chung-Ke Chang, Yu-Hsiang Cheng, Wen-Ching Lin, Ching-Shu Suen, Jen-Hsuan Chang, Ming-Jing Hwang, Kurt Yun Mou, Meng-Sen Huang, Fu An Li
Publikováno v:
Chemistry, an Asian journal. 15(22)
Cancer cells have dramatically increased demands for energy as well as biosynthetic precursors to fuel their restless growth. Enhanced glutaminolysis is a hallmark of cancer metabolism which fulfills these needs. Two glutamine transporters, SLC1A5 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585ce68ef3b5d0ec334867cfb9f728bc
https://pubmed.ncbi.nlm.nih.gov/32996252
https://pubmed.ncbi.nlm.nih.gov/32996252
Autor:
Hou-Wei Chu, Pei-Ei Wu, Chien-Wei Lin, Chen-Yang Shen, Chia-Ni Hsiung, Chung-ke Chang, Shiu-Jie Ling, Ming-Wei Su
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0229922 (2020)
PLoS ONE, Vol 15, Iss 3, p e0229922 (2020)
Diabetes, dyslipidemia and hypertension are important metabolic diseases that impose a great burden on many populations worldwide. However, certain population strata have reduced prevalence for all three diseases, but the underlying mechanisms are po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f3a252d8aea8f67e502bd8dbc0c298
http://europepmc.org/articles/PMC7058291
http://europepmc.org/articles/PMC7058291
Publikováno v:
Nucleic Acids Research
The structure of the DNA duplex is arguably one of the most important biological structures elucidated in modern history. DNA duplex structure is closely associated with essential biological functions such as DNA replication and RNA transcription. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8917085bd80af52100383659cb3205
https://doi.org/10.1093/nar/gky561
https://doi.org/10.1093/nar/gky561