Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chung-Yan Koh"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156341 (2016)
Microfluidic barrier tissue models have emerged as advanced in vitro tools to explore interactions with external stimuli such as drug candidates, pathogens, or toxins. However, the procedures required to establish and maintain these systems can be ch
Externí odkaz:
https://doaj.org/article/1c66f59926cf4c2c91e66e91208954c9
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55044 (2013)
MicroRNAs (miRNAs) are non-coding small RNAs that have cell type and cell context-dependent expression and function. To study miRNAs at single-cell resolution, we have developed a novel microfluidic approach, where flow fluorescent in situ hybridizat
Externí odkaz:
https://doaj.org/article/cc120508ae6f40199dea407521a8c19d
Rapid, Portable, Multiplexed Detection of Bacterial Pathogens Directly from Clinical Sample Matrices
Publikováno v:
Biosensors, Vol 6, Iss 4, p 49 (2016)
Enteric and diarrheal diseases are a major cause of childhood illness and death in countries with developing economies. Each year, more than half of a million children under the age of five die from these diseases. We have developed a portable, micro
Externí odkaz:
https://doaj.org/article/9fb1e51c6e3c4e4c8afde32d465b9eb0
Autor:
Robert J. Meagher, Anchal Sinha, Brooke Harmon, Joseph S. Schoeniger, Tyler P. Eckles, Christopher R. Phaneuf, Kyle J. Seamon, Vinay V. Abhyankar, Chung-Yan Koh
Publikováno v:
Analytical Methods. 11:559-565
The discovery of the RNA-guided DNA nuclease CRISPR-Cas9 has enabled the targeted editing of genomes from diverse organisms, but the permanent and inheritable nature of genome modification also poses immense risks. The potential for accidental exposu
Autor:
Betty Lou Bosano Mangadu, Huu M. Tran, Yooli Kim Light, Christopher R. Phaneuf, Tyler P. Eckles, Chung-Yan Koh, Frank W. Charbonier, Anchal Sinha, Anup K. Singh
Publikováno v:
Biosensorsbioelectronics. 120
The challenges of diagnosing infectious disease, especially in the developing world, and the shortcomings of available instrumentation have exposed the need for portable, easy-to-use diagnostic tools capable of detecting the wide range of causative m
Autor:
Greg J. Sommer, Ulrich Y. Schaff, Chung-Yan Koh, Matthew E. Piccini, Easwaran Ravichandran, Bal Ram Singh, Anup K. Singh, Luisa W. Cheng, Larry H. Stanker
Publikováno v:
Analytical Chemistry
We present an innovative centrifugal microfluidic immunoassay platform (SpinDx) to address the urgent biodefense and public health need for ultrasensitive point-of-care/incident detection of botulinum toxin. The simple, sample-to-answer centrifugal m
Rapid, Portable, Multiplexed Detection of Bacterial Pathogens Directly from Clinical Sample Matrices
Autor:
Betty Lou Bosano Mangadu, Anup K. Singh, Christopher R. Phaneuf, Matthew E. Piccini, Chung-Yan Koh
Publikováno v:
Biosensors; Volume 6; Issue 4; Pages: 49
Biosensors
Biosensors, Vol 6, Iss 4, p 49 (2016)
Biosensors
Biosensors, Vol 6, Iss 4, p 49 (2016)
Enteric and diarrheal diseases are a major cause of childhood illness and death in countries with developing economies. Each year, more than half of a million children under the age of five die from these diseases. We have developed a portable, micro
Autor:
Chung-Yan Koh, Robert J. Meagher, Cameron Ball, Sarah S. Wheeler, Lark L. Coffey, Yooli Kim Light
Publikováno v:
Analytical chemistry. 88(7)
Reverse-transcription-loop-mediated isothermal amplification (RT-LAMP) has frequently been proposed as an enabling technology for simplified diagnostic tests for RNA viruses. However, common detection techniques used for LAMP and RT-LAMP have drawbac
Centrifugal sedimentation immunoassays for multiplexed detection of enteric bacteria in ground water
Waterborne pathogens pose significant threat to the global population and early detection plays an important role both in making drinking water safe, as well as in diagnostics and treatment of water-borne diseases. We present an innovative centrifuga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea8a70d45a3ff6aa39b8710d2e41451
https://europepmc.org/articles/PMC4714988/
https://europepmc.org/articles/PMC4714988/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0156341 (2016)
PLoS ONE, Vol 11, Iss 5, p e0156341 (2016)
Microfluidic barrier tissue models have emerged as advanced in vitro tools to explore interactions with external stimuli such as drug candidates, pathogens, or toxins. However, the procedures required to establish and maintain these systems can be ch