Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chung-Xiou Wang"'
Autor:
Chung S. Yang, Mao Jung Lee, Ah-Ng Tony Kong, Kenneth R. Reuhl, Paul E. Thomas, Tin Oo Khor, Constance Lay Lay Saw, Shiby Paul, Anne Dombrowski, Hong Jin Lee, Chung Xiou Wang, Jae Young So, Amanda K. Smolarek, Nanjoo Suh
Publikováno v:
Molecular Carcinogenesis. 52:514-525
Previous clinical and epidemiological studies of vitamin E have used primarily α-tocopherol for the prevention of cancer. However, γ-tocopherol has demonstrated greater anti-inflammatory and anti-tumor activity than α-tocopherol in several animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391dbcd118a3b2e6a6dc81265a751846
https://doi.org/10.1002/mc.21886
https://doi.org/10.1002/mc.21886
A Novel Gemini Vitamin D Analog Represses the Expression of a Stem Cell Marker CD44 in Breast Cancer
Autor:
Hubert Maehr, Amanda K. Smolarek, Fang Liu, Li Cai, Nanjoo Suh, Xi Zheng, Chung-Xiou Wang, Jae Young So, Hong Jin Lee, Shiby Paul, Milan R. Uskokovic, Allan H. Conney
Publikováno v:
Molecular Pharmacology. 79:360-367
CD44 is a multifunctional transmembrane protein involved in cell proliferation, angiogenesis, invasion, and metastasis. CD44 is identified as a cancer stem cell marker, and the CD44-positive breast cancer cells are enriched in residual breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c58dd7541f66c761a0f0a8f963cb8c
https://doi.org/10.1124/mol.110.068403
https://doi.org/10.1124/mol.110.068403
Autor:
Andrew J. DeCastro, Barbara Simi, Shiby Paul, Hong Jin Lee, Renping Zhou, Nanjoo Suh, Jae Young So, Agnes M. Rimando, Chung Xiou Wang, Amanda K. Smolarek
Publikováno v:
Carcinogenesis. 31:1272-1278
Stilbenes are phytochemicals present in grapes, berries, peanuts and red wine. A widely studied stilbene, resveratrol (trans-3,5,4'-trihydroxystilbene), has been shown to exert antioxidant, anti-inflammatory, chemopreventive and antiaging effects in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d692c2dbafe987813ebd6224b859279e
https://doi.org/10.1093/carcin/bgq004
https://doi.org/10.1093/carcin/bgq004
Autor:
Bandaru S. Reddy, Barbara Simi, Levy Kopelovich, Vernon E. Steele, Chinthalapally V. Rao, Jagan M.R. Patlolla, Xiaoping Liu, Nengtai Ouyang, Basil Rigas, Chung Xiou Wang
Publikováno v:
Molecular Cancer Therapeutics. 5:1530-1538
Nitric oxide–releasing nonsteroidal anti-inflammatory drugs (NO-NSAID) are promising chemoprevention agents; unlike conventional NSAIDs, they seem free of appreciable adverse effects, while they retain beneficial activities of their parent compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612c59e2d7bdf3f66a6e5df6c25bed57
https://doi.org/10.1158/1535-7163.mct-06-0061
https://doi.org/10.1158/1535-7163.mct-06-0061
Autor:
Xi Zheng, Tin Oo Khor, Levy Kopelovich, Chung Xiou Wang, Vernon E. Steele, Chinthalapally V. Rao, Bandaru S. Reddy, Ah-Ng Tony Kong
Publikováno v:
Cancer Research. 66:4542-4546
Preclinical and clinical studies have provided evidence that aspirin, celecoxib, (cyclooxygenase-2 inhibitor), and statins (3-hydroxy-3-methylglutaryl CoA reductase inhibitors) inhibit colon carcinogenesis. Chronic use of high doses of these agents m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371292d268d3700d8293ea773ed72e7c
https://doi.org/10.1158/0008-5472.can-05-4428
https://doi.org/10.1158/0008-5472.can-05-4428
Autor:
C. Clifford Conaway, Defa Tian, Chung Xiou Wang, Stephen S. Hecht, Yang Ming Yang, Brian Pittman, Joel E. Schwartz, Fung Lung Chung, Edward J. McIntee
Publikováno v:
Cancer Research. 65:8548-8557
We have shown previously that naturally occurring isothiocyanates derived from cruciferous vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced by tobacco carcinogens in A/J mice at the post-initiation stage. The tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f561e692c0043072b2a18dc696f947f
https://doi.org/10.1158/0008-5472.can-05-0237
https://doi.org/10.1158/0008-5472.can-05-0237
Autor:
Joel Reinhardt, Dhimant Desai, Emerich S. Fiala, Rama S. Sodum, Ock Soon Sohn, Chung Xiou Wang, Junji Tsurutani, Cesar Aliaga, Phillip A. Dennis, Eleanore Seibert, Karam El-Bayoumy
Publikováno v:
Carcinogenesis. 26:605-612
The development of effective chemopreventive agents against cigarette smoke-induced lung cancer could be greatly facilitated by the availability of suitable laboratory animal models. Here we report that male Hartley guinea pigs treated with cigarette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f25f4f8b2efe9a1e33e2b0c6f3ed9d6
https://doi.org/10.1093/carcin/bgh341
https://doi.org/10.1093/carcin/bgh341
Autor:
Gary M. Williams, Brian Pittman, Feng-Qi Luo, Michael J. Iatropoulos, Alan M. Jeffrey, Chung-Xiou Wang
Publikováno v:
Archives of Toxicology. 73:394-402
In previous exposure-response studies, we have documented non-linearities for some of the early effects in rat liver of diethylnitrosamine (DEN) and a near no-effect levels for initiation of promotable liver neoplasms at the lowest cumulative exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27746ee8e5ecc71944c6939bb0169f32
https://doi.org/10.1007/s002040050679
https://doi.org/10.1007/s002040050679
Autor:
Michael J. Iatropoulos, S. Thompson, Chung Xiou Wang, Alan M. Jeffrey, B. Pittman, Rolf Gebhardt, M. Palasch, Gary M. Williams
Publikováno v:
Toxicological Sciences. 45:152-161
The dose responses for several effects of low-level limited exposures to 2-acetylaminofluorene (AAF) in the livers of male Fischer 344 rats were measured and a subsequent phenobarbital tumor promotion regimen was used to manifest initiation of carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39ae9fa1189b6db37e66e77dc1044fe2
https://doi.org/10.1093/toxsci/45.2.152
https://doi.org/10.1093/toxsci/45.2.152
Autor:
Yang-Ming, Yang, C Clifford, Conaway, J W, Chiao, Chung-Xiou, Wang, Shantu, Amin, John, Whysner, Wei, Dai, Joel, Reinhardt, Fung-Lung, Chung
Publikováno v:
Cancer research. 62(1)
Recent studies in cell culture have shown that isothiocyanates (ITCs) induce apoptosis via activation of mitogen-activated protein (MAP) kinases and p53 pathways, suggesting a potential for ITCs or their conjugates to inhibit tumorigenesis during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc2dcf23519b63db4e8239329239dd62
https://pubmed.ncbi.nlm.nih.gov/11782348
https://pubmed.ncbi.nlm.nih.gov/11782348