Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Chung-Seog Song"'
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 6, Pp 353-363 (2019)
Abstract Hyperproliferation of prostate transition‐zone epithelial and stromal cells leads to benign prostate hyperplasia (BPH), a prevalent pathology in elderly men. Senescent cells in BPH tissue induce a senescence‐associated secretory phenotyp
Externí odkaz:
https://doaj.org/article/22e204fefad54223aa52273fcf0b0e93
Publikováno v:
Cancers. 14(4)
Organ-confined prostate cancer of low-grade histopathology is managed with radiation, surgery, active surveillance, or watchful waiting and exhibits a 5-year overall survival (OS) of 95%, while metastatic prostate cancer (PCa) is incurable, holding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fee5b630bac50e25c4a760f7422ea94
https://pubmed.ncbi.nlm.nih.gov/35205640
https://pubmed.ncbi.nlm.nih.gov/35205640
Autor:
Alvin M. Matsumoto, Maria Gaczynska, Bandana Chatterjee, Pawel A. Osmulski, Colm Morrissey, Shoulei Jiang, Brett T. Marck, Chung-Seog Song, Elahe A. Mostaghel, Sulgi Park
Publikováno v:
Journal of the Endocrine Society
The prostate-expressed sulfotransferase SULT2B1b (SULT2B) regulates intracrine androgen homeostasis by mediating 3β-sulfation of DHEA, thus reducing the precursor pool in the androgen biosynthesis pathway. We explored how loss of SULT2B might influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b56f44fb95996527bad460027ae4bf
http://europepmc.org/articles/PMC7208293
http://europepmc.org/articles/PMC7208293
Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer
Autor:
Chung-Seog Song, Chiou Miin Wang, Elahe A. Mostaghel, Alvin M. Matsumoto, Brett T. Marck, Maria Gaczynska, Yi Chen, Bandana Chatterjee, Chun-Lin Lin, Pawel A. Osmulski, Colm Morrissey, Sulgi Park, Shoulei Jiang
Publikováno v:
Endocrinology
SULT2B1b (SULT2B) is a prostate-expressed hydroxysteroid sulfotransferase, which may regulate intracrine androgen homeostasis by mediating 3β-sulfation of dehydroepiandrosterone (DHEA), the precursor for 5α-dihydrotestosterone (DHT) biosynthesis. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df4717c1cd39ea10010e7dc509e01ff
https://doi.org/10.1210/endocr/bqz042
https://doi.org/10.1210/endocr/bqz042
Publikováno v:
FASEB bioAdvances
FASEB BioAdvances, Vol 1, Iss 6, Pp 353-363 (2019)
FASEB BioAdvances, Vol 1, Iss 6, Pp 353-363 (2019)
Hyperproliferation of prostate transition‐zone epithelial and stromal cells leads to benign prostate hyperplasia (BPH), a prevalent pathology in elderly men. Senescent cells in BPH tissue induce a senescence‐associated secretory phenotype (SASP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9177987a6d1e3d896bb5c9aede49c5
https://doi.org/10.1096/fba.2018-00084
https://doi.org/10.1096/fba.2018-00084
Prostate Cancer Stimulation by a Novel Liver X Receptor (LXRa)-Estrogen Related Receptor (ERRa) Axis
Autor:
Bandana Chatterjee, Chung-Seog Song
Publikováno v:
Journal of the Endocrine Society
Background: Liver X Receptors (LXRα, β) are oxysterol sensing nuclear receptors that regulate lipogenesis, cholesterol homeostasis and immune cell function. While oxysterols are agonist ligands of LXRs, sulfated oxysterols, catalytically produced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ebfa800a6fe629e8748b6cd5c32c8c
https://doi.org/10.1210/jendso/bvab048.2107
https://doi.org/10.1210/jendso/bvab048.2107
Autor:
Chandra Prakash, Sulgi Park, Jodie Cropper, Chung-Seog Song, Shoulei Jiang, Bandana Chatterjee, Baltazar Zuniga
Publikováno v:
Nuclear Receptor Research, Vol 2, Pp 1-20 (2015)
Orally delivered small-molecule therapeutics are metabolized in the liver and intestine by phase I and phase II drug-metabolizing enzymes (DMEs), and transport proteins coordinate drug influx (phase 0) and drug/drug-metabolite efflux (phase III). Gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54f377dd891aafd661713301cae7ed4
https://pubmed.ncbi.nlm.nih.gov/27478824
https://pubmed.ncbi.nlm.nih.gov/27478824
Autor:
Jungmi, Ahn, Sulgi, Park, Baltazar, Zuniga, Alakesh, Bera, Chung Seog, Song, Bandana, Chatterjee
Publikováno v:
Vitamins and hormones. 100
Metastatic castration-resistant prostate cancer (mCRPC) is a progressive, noncurable disease induced by androgen receptor (AR) upon its activation by tumor tissue androgen, which is generated from adrenal steroid dehydroepiandrosterone (DHEA) through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c99e3197145f78ecbe9b28092df117da
https://pubmed.ncbi.nlm.nih.gov/26827958
https://pubmed.ncbi.nlm.nih.gov/26827958
Metastatic castration-resistant prostate cancer (mCRPC) is a progressive, noncurable disease induced by androgen receptor (AR) upon its activation by tumor tissue androgen, which is generated from adrenal steroid dehydroepiandrosterone (DHEA) through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec40ef2d11c50e4e74be9535582449c4
https://doi.org/10.1016/bs.vh.2015.10.012
https://doi.org/10.1016/bs.vh.2015.10.012
Publikováno v:
Molecular Endocrinology. 22:273-286
Increased androgen receptor (AR) levels are associated with prostate cancer progression to androgen independence and therapy resistance. Evidence has suggested that chronic inflammation is closely linked to various cancers including prostate cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c271e2c27524c5a0a11852ffcf786a
https://doi.org/10.1210/me.2007-0332
https://doi.org/10.1210/me.2007-0332